Dynamic regulation of dopamine and serotonin responses to salient stimuli during chronic haloperidol treatment

International Journal of Neuropsychopharmacology

Volumn 14, Issue 10, 2011, Pages 1327-1339

  Amato, Davide ^a   Natesan, Sridhar ^b   Yavich, Leonid ^a   Kapur, Shitij ^a   Müller, Christian P ^a,c  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

Dopamine; haloperidol; serotonin; treatment efficacy failure

Indexed keywords

BIOLOGICAL MARKER; DOPAMINE; DOPAMINE 2 RECEPTOR; HALOPERIDOL; NEUROTRANSMITTER; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APPETITE; ARTICLE; CONTROLLED STUDY; DOPAMINE RELEASE; DOPAMINERGIC SYSTEM; LOCOMOTION; MALE; MEDIAL FOREBRAIN BUNDLE; MICRODIALYSIS; NONHUMAN; NUCLEUS ACCUMBENS; OSMOTIC MINIPUMP; POTENTIOMETRY; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; RECEPTOR OCCUPANCY; SEROTONINERGIC SYSTEM; SHORT COURSE THERAPY; TREATMENT DURATION; TREATMENT FAILURE; TREATMENT RESPONSE;

ANIMALS; ANTIPSYCHOTIC AGENTS; APPETITIVE BEHAVIOR; BEHAVIOR, ANIMAL; BRAIN; CAUDATE NUCLEUS; DOPAMINE; DRUG ADMINISTRATION SCHEDULE; EXPLORATORY BEHAVIOR; HALOPERIDOL; INFUSION PUMPS, IMPLANTABLE; MALE; MICRODIALYSIS; MOTOR ACTIVITY; NUCLEUS ACCUMBENS; PAIN THRESHOLD; PREFRONTAL CORTEX; PUTAMEN; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN; TIME FACTORS; TREATMENT FAILURE;

EID: 80054972190     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145711000010     Document Type: Article

References (49)

1. Abercrombie ED, Keefe KA, DiFrischia DS, Zigmond MJ (1989). Differential effect of stress on in vivo dopamine release in striatum, nucleus accumbens, and medial frontal cortex. Journal of Neurochemistry 52, 1655-1658. (Pubitemid 19109526)
2. Andreasen NC, O'Leary DS, Flaum M, Nopoulos P, et al. (1997). Hypofrontality in schizophrenia : distributed dysfunctional circuits in neuroleptic naive patients. Lancet 349, 1730-1734. (Pubitemid 27252672)
3. Badiani A, Oates MM, Day HE, Watson SJ, et al. (1998). Amphetamine induced behavior, dopamine release, and c-fos mRNA expression: modulation by environmental novelty. Journal of Neuroscience 18, 10579-10593. (Pubitemid 29016576)
4. Bardo MT, Bowling SL, Pierce RC (1990). Changes in locomotion and dopamine neurotransmission following amphetamine, haloperidol, and exposure to novel environmental stimuli. Psychopharmacology 101, 338-343. (Pubitemid 20193371)
5. Bassareo V, Di Chiara G (1997). Differential influence of associative and nonassociative learning mechanisms on the responsiveness of prefrontal and accumbal dopamine transmission to food stimuli in rats fed ad libitum. Journal of Neuroscience 17, 851-861. (Pubitemid 27024596)
6. Benoit-Marand M, Borrelli E, Gonon F (1991). Inhibition of dopamine release via presesynaptic D2 receptors : time course and functional characteristics in vivo. Journal of Neuroscience 23, 9134-9141.
7. Berridge KC (2007). The debate over dopamine's role in reward: the case for incentive salience. Psychopharmacology 191, 391-431. (Pubitemid 46355895)
8. Buckley PF, Correll CU, Miller AL (2007). First-episode psychosis: a window of opportunity for best practices. CNS Spectrums 12, 1-12.
9. Carlsson A (2006). The neurochemical circuitry of schizophrenia. Pharmacopsychiatry 1, S10-S14. (Pubitemid 43357100)
10. Cass WA, Gerhardt GA (1994). Direct in vivo evidence that D2 dopamine receptors can modulate dopamine uptake. Neurosciece Letters 176, 259-263. (Pubitemid 24241870)
11. Dazzi L, Seu E, Cherchi G, Biggio G (2004). Inhibition of stress-induced dopamine output in the rat prefrontal cortex by chronic treatment with olanzapine. Biological Psychiatry 55, 477-483. (Pubitemid 38338535)
12. De Deurwaerdere P, Spampinato U (1999). Role of serotonin(2A) and serotonin(2B/2C) receptor subtypes in the control of accumbal and striatal dopamine release elicited in vivo by dorsal raphe nucleus electrical stimulation. Journal of Neurochemistry 73, 1033-1042. (Pubitemid 29395459)
13. Devoto P, Flore G (2006). On the origin of cortical dopamine: is it a co-transmitter in noradrenergic neurons? Current Neuropharmacology 4, 115-125.
14. Erlanson-Albertsson C (2005). How palatable food disrupts appetite regulation. Basic & Clinical Pharmacology and Toxicology 97, 61-73. (Pubitemid 41021104)
15. Feenstra MG, Botterblom MH (1996). Rapid sampling of extracellular dopamine in the rat prefrontal cortex during food consumption, handling and exposure to novelty. Brain Research 742, 17-24. (Pubitemid 27016003)
16. Hoebel BG (1985). Brain neurotransmitters in food and drug reward. American Journal of Clinical Nutrition 42, 1133-1150. (Pubitemid 16148065)
17. Ichikawa J, Meltzer HY (1990a). Apomorphine does not reverse reduced basal dopamine release in rat striatum and nucleus accumbens after chronic haloperidol treatment. Brain Research 507, 138-142. (Pubitemid 20033837)
18. Ichikawa J, Meltzer HY (1990b). The effect of chronic clozapine and haloperidol on basal dopamine release and metabolism in rat striatum and nucleus accumbens studied by in vivo microdialysis. European Journal of Pharmacology 176, 371-374. (Pubitemid 20076292)
19. Ichikawa J, Meltzer HY (2000). The effect of serotonin(1A) receptor agonism on antipsychotic drug-induced dopamine release in rat striatum and nucleus accumbens. Brain Research 858, 252-263. (Pubitemid 30119986)
20. Imperato A, Puglisi-Allegra S, Casolini P, Angelucci L (1991). Changes in brain dopamine and acetylcholine release during and following stress are independent of the pituitary-adrenocortical axis. Brain Research 538, 111-117.
21. Kapur S (2003). Psychosis as a state of aberrant salience : A framework linking biology, phenomenology, and pharmacology in schizophrenia. American Journal of Psychiatry 160, 13-23. (Pubitemid 36042420)
22. Kapur S, Mamo D (2003). Half a century of antipsychotics and still a central role for dopamine D2 receptors. Progress in Neuro-Psychopharmacology & Biological Psychiatry 27, 1081-1090. (Pubitemid 37464954)
23. Kapur S, VanderSpek SC, Brownlee BA, Nobrega JN (2003). Antipsychotic dosing in preclinical models is often unrepresentative of the clinical condition : A suggested solution based on in vivo occupancy. Journal of Pharmacology and Experimental Therapeutics 305, 625-631. (Pubitemid 36459179)
24. Kilpatrick GJ, Hagan RM, Gale JD (1996). 5-HT3 and 5-HT4 receptors in terminal regions of the mesolimbic system. Behavioural Brain Research 73, 11-13. (Pubitemid 26008756)
25. Klitenick MA, Taber MT, Fibiger HC (1996). Effects of chronic haloperidol on stress- and stimulation-induced increases in dopamine release : tests of the depolarization block hypothesis. Neuropsychopharmacology 15, 424-428. (Pubitemid 26342926)
26. Lane RF, Blaha CD (1987). Chronic haloperidol decreases dopamine release in striatum and nucleus accumbens in vivo : depolarization block as a possible mechanism of action. Brain Research Bulletin 18, 135-138. (Pubitemid 17017506)
27. Lieberman JA, Stroup TS, McEvoy JP, Swartz MS, et al. (2005). Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. New England Journal of Medicine 353, 1209-1223. (Pubitemid 41345943)
28. Mayfield RD, Zahniser NR (2001). Dopamine D2 receptor regulation of the dopamine transporter expressed in Xenopus laevis oocytes is voltage-independent. Molecular Pharmacology 59, 113-121. (Pubitemid 32043092)
29. Meiergerd SM, Patterson TA, Schenk JO (1993). D2 receptors may modulate the function of the striatal transporter for dopamine: kinetic evidence from studies in vitro and in vivo. Journal of Neurochemistry 61, 764-767. (Pubitemid 23215826)
30. Mereu G, Lilliu V, Vargiu P, Muntoni AL, Diana M, Gessa GL (1995). Depolarization inactivation of dopamine neurons : an artifact? Journal of Neuroscience 15, 1144-1149.
31. Moghaddam B, Bunney BS (1993). Depolarization inactivation of dopamine neurons: terminal release characteristics. Synapse 14, 195-200. (Pubitemid 23204945)
32. Mü ller CP, Jacobs BL (2010). Handbook of the Behavioral Neurobiology of Serotonin. London: Academic Press.
33. Murugaiah K, Theodorou A, Mann S, Clow A, et al. (1982). Chronic continuous administration of neuroleptic drugs alters cerebral dopamine receptors and increases spontaneous dopaminergic action in the striatum. Nature 296, 570-572. (Pubitemid 12058404)
34. Parsons LH, Schad CA, Justice JB (1993). Co-administration of the D2 antagonist pimozide inhibits up-regulation of dopamine release and uptake induced by repeated cocaine. Journal of Neurochemistry 60, 376-379. (Pubitemid 23006744)
35. Paxinos G, Watson C (1986). The Rat Brain in Stereotactic Coordinates. New York: Academic Press.
36. Piazza PV, Rouge-Pont F, Deminiere JM, Kharoubi M, et al. (1991). Dopaminergic activity is reduced in the prefrontal cortex and increased in the nucleus accumbens of rats predisposed to develop amphetamine self-administration. Brain Research 567, 169-174.
37. Pum ME, Carey RJ, Huston JP, Mü ller CP (2007). Dissociating effects of cocaine and d-amphetamine on dopamine and serotonin in the perirhinal, entorhinal, and prefrontal cortex of freely moving rats. Psychopharmacology (Berlin) 193, 375-390. (Pubitemid 47063512)
38. Pum ME, Huston JP, De Souza Silva MA, Müller CP (2008). Visual sensory-motor gating by serotonin activation in the medial prefrontal and occipital, but not in the rhinal, cortices in rats. Neuroscience 153, 361-372.
39. Ramsey PH (1993) Multiple comparisons of independent means. In : Edwards LK (Eds), Applied Analysis of Variance in Behavioral Science (pp. 25-61). New York: Marcel Dekker.
40. Robinson TE, Becker JB Young EA, Akil H, et al. (1987). The effects of footshock stress on regional brain dopamine metabolism and pituitary beta-endorphin release in rats previously sensitized to amphetamine. Neuropharmacology 26, 679-691. (Pubitemid 17100433)
41. Samaha AN, Reckless GE, Seeman P, Diwan M, et al. (2008). Less is more: antipsychotic drug effects are greater with transient rather than continuous delivery. Biological Psychiatry 64, 145-152.
42. Samaha AN, Seeman P, Stewart J, Rajabi H, et al. (2007). 'Breakthrough' dopamine supersensitivity during ongoing antipsychotic treatment leads to treatment failure over time. Journal of Neuroscience 27, 2979-2986. (Pubitemid 46438984)
43. Schooler NR (2003). Relapse and rehospitalization : comparing oral and depot antipsychotics. Journal of Clinical Psychiatry 16, 14-17. (Pubitemid 37523323)
44. Seeman P, Weinshenker D, Quirion R, Srivastava LK, et al. (2005). Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis. Proceedings of the National Academy of Sciences USA 102, 3513-3518. (Pubitemid 40328076)
45. Sivam SP (1995). Dopaminergic modulation of serotonin metabolism in rat striatum : A study with dopamine uptake inhibitor GBR-12909. Life Science 56, PL467-PL472.
46. Stephan KE, Riera JJ, Deco G, Horwitz B (2008). The brain connectivity workshops: moving the frontiers of computational systems neuroscience. NeuroImage 42, 1-9.
47. Thierry AM, Tassin JP, Blanc G, Glowinski J (1976). Selective activation of mesocortical DA system by stress. Nature 263, 242-244.
48. Yavich L, Forsberg MM, Karayiorgou M, Gogos JA, et al. (2007). Site-specific role of catechol-O-methyltransferase in dopamine overflow within prefrontal cortex and dorsal striatum. Journal of Neuroscience 27, 10196-10209.
49. Zhang W, Tilson H, Stachowiak MK, Hong JS (1989). Repeated haloperidol administration changes basal release of striatal dopamine and subsequent response to haloperidol challenge. Brain Research 484, 389-392. (Pubitemid 19100105)