Natural Products Genomics: A novel approach for the discovery of anti-cancer therapeutics

Journal of Pharmacological and Toxicological Methods

Volumn 64, Issue 3, 2011, Pages 217-225

  Monks, N R ^a   Li, B ^a   Gunjan, S ^b   Rogers, D T ^b   Kulshrestha, M ^a   Falcone, D L ^a,c   Littleton, J M ^a,b  

^a Naprogenix Inc   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF MASSACHUSETTS LOWELL   (United States)

Author keywords

Activation Tagging Mutagenesis; Directed elicitation; Directed evolution; High Throughput Differential Screening; Natural Products Genomics; Vinca alkaloids

Indexed keywords

CATHARANTHUS ROSEUS EXTRACT; NATURAL PRODUCT; VINCA ALKALOID;

ARTICLE; CATHARANTHUS ROSEUS; COMBINATORIAL CHEMISTRY; GAIN OF FUNCTION MUTATION; GENE EXPRESSION; HAIRY ROOT CULTURE; HIGH THROUGHPUT SCREENING; NONHUMAN; PLANT BIOTECHNOLOGY; PLANT CELL CULTURE; PLANT GENOME; PLANT LEAF; PLANT METABOLISM; PLANT ROOT; PLANT YIELD; TOBACCO; TRANSGENE;

ANTINEOPLASTIC AGENTS; BIOLOGICAL AGENTS; BIOTECHNOLOGY; CATHARANTHUS; CELL CULTURE TECHNIQUES; DRUG DISCOVERY; DRUG INDUSTRY; GENOME, PLANT; HUMANS; MUTAGENESIS; NEOPLASMS; PHARMACEUTICAL PREPARATIONS; PHYTOTHERAPY; PLANT CELLS; PLANTS, MEDICINAL; TOBACCO; TRANSGENES;

CATHARANTHUS ROSEUS; NICOTIANA TABACUM; VINCA;

EID: 80054964116     PISSN: 10568719     EISSN: 1873488X     Source Type: Journal    
DOI: 10.1016/j.vascn.2011.04.002     Document Type: Article

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