Limbal epithelial stem/progenitor cells attract stromal niche cells by SDF-1/CXCR4 signaling to prevent differentiation

Stem Cells

Volumn 29, Issue 11, 2011, Pages 1874-1885

  Xie, Hua Tao ^a,b   Chen, Szu Yu ^a   Li, Gui Gang ^a,c   Tseng, Scheffer C G ^a  

^a OCULAR SURFACE CENTER   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Basement membrane; CXCR4; Limbus; SDF 1; Stem cell; Stem cell niche; Three dimensional culture

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR7; STROMAL CELL DERIVED FACTOR 1;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL FATE; CELL FUNCTION; CELL GROWTH; CELL INTERACTION; CELL ISOLATION; CELL RENEWAL; CELL SHAPE; CELL SIZE; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; LIMBAL EPITHELIAL STEM CELL; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; STEM CELL; STEM CELL NICHE; STROMA CELL;

ADOLESCENT; ADULT; AGED; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELLS, CULTURED; CHEMOKINE CXCL12; COLLAGENASES; ENDOPEPTIDASES; EPITHELIUM, CORNEAL; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; LIMBUS CORNEAE; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CXCR; RECEPTORS, CXCR4; SIGNAL TRANSDUCTION; STEM CELLS; STROMAL CELLS; YOUNG ADULT;

EID: 80054956645     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.743     Document Type: Article

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