메뉴 건너뛰기




Volumn 58, Issue 3, 2011, Pages 233-240

Drug resistance and viral tropism in HIV-1 subtype C-infected patients in KwaZulu-Natal, South Africa: Implications for future treatment options

Author keywords

antiretroviral drug resistance; coreceptor use; HAART failing patients; HAART na ve patients; viral tropism

Indexed keywords

CHEMOKINE RECEPTOR CCR5 ANTAGONIST; CHEMOKINE RECEPTOR CXCR4; DELAVIRDINE; DIDANOSINE; EFAVIRENZ; EMTRICITABINE; ETRAVIRINE; LAMIVUDINE; NEVIRAPINE; STAVUDINE; THYMIDINE; ZIDOVUDINE;

EID: 80054948254     PISSN: 15254135     EISSN: 10779450     Source Type: Journal    
DOI: 10.1097/QAI.0b013e318228667f     Document Type: Article
Times cited : (21)

References (43)
  • 1
    • 36549011407 scopus 로고    scopus 로고
    • UNAIDS Accessed February 18, 2008
    • UNAIDS. AIDS epidemic update. 2007. Available at: www.unaids.org. Accessed February 18, 2008.
    • (2007) AIDS Epidemic Update
  • 4
    • 80054886337 scopus 로고    scopus 로고
    • UNAIDS Accessed May 11, 2011
    • UNAIDS Global Report. Factsheet-Sub-Saharan Africa. 2010. http://www.unaids.org/en/media/unaids/contentassets/documents/factsheet/2010/ 20101123-FS-SSA-em-en.pdf. Accessed May 11, 2011.
    • (2010) Global Report. Factsheet-Sub-Saharan Africa
  • 7
    • 84857059764 scopus 로고    scopus 로고
    • WHO recommendations for clinical mentoring to support scale-up of HIV care, antiretroviral therapy and prevention in resource-constrained settings
    • WHO recommendations for clinical mentoring to support scale-up of HIV care, antiretroviral therapy and prevention in resource-constrained settings. WHO Guidelines. 2006. Available at: http://www.who.int/hiv/pub/guidelines/ clinicalmentoring.pdf.
    • (2006) WHO Guidelines
  • 8
    • 70349303657 scopus 로고    scopus 로고
    • Rate of accumulation of thymidine analogue mutations in patients continuing to receive virologically failing regimens containing zidovudine or stavudine: Implications for antiretroviral therapy programs in resource-limited settings
    • Cozzi-Lepri A, Phillips AN, Martinez-Picado J, et al. Rate of accumulation of thymidine analogue mutations in patients continuing to receive virologically failing regimens containing zidovudine or stavudine: implications for antiretroviral therapy programs in resource-limited settings. J Infect Dis. 2009;200:687-697.
    • (2009) J Infect Dis , vol.200 , pp. 687-697
    • Cozzi-Lepri, A.1    Phillips, A.N.2    Martinez-Picado, J.3
  • 9
    • 67650395240 scopus 로고    scopus 로고
    • The public health approach to identify antiretroviral therapy failure: High-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing firstline antiretroviral therapy
    • Hosseinipour MC, van Oosterhout JGG,Weigel R, et al. The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing firstline antiretroviral therapy. AIDS. 2009;23:1127-1134.
    • (2009) AIDS , vol.23 , pp. 1127-1134
    • Hosseinipour, M.C.1    Van Oosterhout, J.G.G.2    Weigel, R.3
  • 11
    • 77949363519 scopus 로고    scopus 로고
    • Varied patterns of HIV-1 drug resistance on failing first-line antiretroviral therapy in South Africa
    • Wallis C, Mellors JW, Venter F, et al. Varied patterns of HIV-1 drug resistance on failing first-line antiretroviral therapy in South Africa. J Acquir Immune Defic Syndr. 2010;53:480-484.
    • (2010) J Acquir Immune Defic Syndr , vol.53 , pp. 480-484
    • Wallis, C.1    Mellors, J.W.2    Venter, F.3
  • 13
    • 0038805436 scopus 로고    scopus 로고
    • High frequency of syncytium-inducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment
    • DOI 10.1128/JVI.77.13.7682-7688.2003
    • Johnston ER, Zijenah LS, Mutetwa S, et al. High frequency of syncytiuminducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment. J Virol. 2003;77:7682-7688. (Pubitemid 36734540)
    • (2003) Journal of Virology , vol.77 , Issue.13 , pp. 7682-7688
    • Johnston, E.R.1    Zijenah, L.S.2    Mutetwa, S.3    Kantor, R.4    Kittinunvorakoon, C.5    Katzenstein, D.A.6
  • 14
  • 16
    • 2442765375 scopus 로고    scopus 로고
    • Phenotypic characteristics of human immunodeficiency virus type 1 subtype C isolates of ethiopian AIDS patients
    • DOI 10.1089/088922299310944
    • Bjorndal A, Sonnerborg A, Tscherning C, et al. Phenotypic characteristics of human immunodeficiency virus type 1 subtype C isolates of Ethiopian AIDS patients. Aids Res Hum Retroviruses. 1999;15:647-653. (Pubitemid 29205668)
    • (1999) AIDS Research and Human Retroviruses , vol.15 , Issue.7 , pp. 647-653
    • Bjorndal, A.1    Sonnerborg, A.2    Tscherning, C.3    Albert, J.4    Fenyo, E.M.5
  • 17
    • 0034608197 scopus 로고    scopus 로고
    • Absence of coreceptor switch with disease progression in human immunodeficiency virus infections in India
    • DOI 10.1006/viro.2000.0297
    • Cecilia D, Kulkarni SS, Tripathy SP, et al. Absence of coreceptor switch with disease progression in human immunodeficiency virus infections in India. Virology. 2000;271:253-258. (Pubitemid 30461303)
    • (2000) Virology , vol.271 , Issue.2 , pp. 253-258
    • Cecilia, D.1    Kulkarni, S.S.2    Tripathy, S.P.3    Gangakhedkar, R.R.4    Paranjape, R.S.5    Gadkari, D.A.6
  • 19
    • 33646491049 scopus 로고    scopus 로고
    • HIV-1 subtype C in vitro growth and coreceptor utilization
    • Ndung'u T, Sepako E, McLane MF, et al. HIV-1 subtype C in vitro growth and coreceptor utilization. Virology. 2006;347:247-260.
    • (2006) Virology , vol.347 , pp. 247-260
    • Ndung'U, T.1    Sepako, E.2    McLane, M.F.3
  • 20
    • 0032519399 scopus 로고    scopus 로고
    • Differences in chemokine coreceptor usage between genetic subtypes of HIV-1
    • Tscherning CA, Alaeus RF, Fredriksson A, et al. Differences in chemokine coreceptor usage between genetic subtypes of HIV-1. Virology. 1998;241:181-188.
    • (1998) Virology , vol.241 , pp. 181-188
    • Tscherning, C.A.1    Alaeus, R.F.2    Fredriksson, A.3
  • 21
    • 84858159077 scopus 로고    scopus 로고
    • An enhanced-sensitivity TrofileTM HIV coreceptor tropism assay for selecting patients for therapy with entry inhibitors targeting CCR5: A review of analytical and clinical studies
    • Reeves JD, Coakley E, Petropoulos CJ, et al. An enhanced-sensitivity TrofileTM HIV coreceptor tropism assay for selecting patients for therapy with entry inhibitors targeting CCR5: a review of analytical and clinical studies. J Viral Entry. 2009;3:94-102.
    • (2009) J Viral Entry , vol.3 , pp. 94-102
    • Reeves, J.D.1    Coakley, E.2    Petropoulos, C.J.3
  • 22
    • 55049106689 scopus 로고    scopus 로고
    • Technical validation of an enhanced sensitivity Trofile HIV co-receptor tropism assay for selecting patients for therapy with entry inhibitors targeting CCR5
    • Trinh L, Han D, Huang W, et al. Technical validation of an enhanced sensitivity Trofile HIV co-receptor tropism assay for selecting patients for therapy with entry inhibitors targeting CCR5. Antiviral Ther. 2008;13:128.
    • (2008) Antiviral Ther , vol.13 , pp. 128
    • Trinh, L.1    Han, D.2    Huang, W.3
  • 24
    • 33646443202 scopus 로고    scopus 로고
    • Emergence of CXCR4-using human immunodeficiency virus type 1 (HIV-1) variants in a minority of HIV-1-infected patients following treatment with the CCR5 antagonist maraviroc is from a pretreatment CXCR4-using virus reservoir
    • Westby M, Lewis M, Whitcomb J, et al. Emergence of CXCR4-using human immunodeficiency virus type 1 (HIV-1) variants in a minority of HIV-1-infected patients following treatment with the CCR5 antagonist maraviroc is from a pretreatment CXCR4-using virus reservoir J Virol. 2006;80:4909-4920.
    • (2006) J Virol , vol.80 , pp. 4909-4920
    • Westby, M.1    Lewis, M.2    Whitcomb, J.3
  • 25
    • 70349319355 scopus 로고    scopus 로고
    • Functional and genetic analysis of coreceptor usage by dualtropic HIV-1 subtype C isolates
    • Singh A, Page T, Moore PL, et al. Functional and genetic analysis of coreceptor usage by dualtropic HIV-1 subtype C isolates. Virology. 2009; 393:56-67.
    • (2009) Virology , vol.393 , pp. 56-67
    • Singh, A.1    Page, T.2    Moore, P.L.3
  • 26
    • 34547781750 scopus 로고    scopus 로고
    • MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0
    • DOI 10.1093/molbev/msm092
    • Tamura K, Dudley J, Nei M, Kumar S. MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0. Mol Biol Evol. 2007;24: 1596-1599. (Pubitemid 47236692)
    • (2007) Molecular Biology and Evolution , vol.24 , Issue.8 , pp. 1596-1599
    • Tamura, K.1    Dudley, J.2    Nei, M.3    Kumar, S.4
  • 27
    • 33750979833 scopus 로고    scopus 로고
    • Genetic characteristics of the V3 region associated with CXCR4 usage in HIV-1 subtype C isolates
    • DOI 10.1016/j.virol.2006.07.030, PII S0042682206005071
    • Coetzer M, Cilliers T, Ping LH, et al. Genetic characteristics of the V3 region associated with CXCR4 usage in HIV-1 subtype C isolates. Virology. 2006;356:95-105. (Pubitemid 44750034)
    • (2006) Virology , vol.356 , Issue.1-2 , pp. 95-105
    • Coetzer, M.1    Cilliers, T.2    Ping, L.-H.3    Swanstrom, R.4    Morris, L.5
  • 28
    • 0028950499 scopus 로고
    • Simple determination of human immunodeficiency virus type 1 syncytium-inducing V3 genotype by PCR
    • Fouchier RA, Brouwer M, Broersen SM, et al. Simple determination of human immunodeficiency virus type 1 syncytium-inducing V3 genotype by PCR. J Clin Microbiol. 1995;33:906-911.
    • (1995) J Clin Microbiol , vol.33 , pp. 906-911
    • Fouchier, R.A.1    Brouwer, M.2    Broersen, S.M.3
  • 29
    • 0026606727 scopus 로고
    • Phenotype-associated sequence variationin the third variable domain of the human immunodeficiency virus type 1 gp 120 molecule
    • Fouchier RA, Groenink M, Kootstra NN, et al. Phenotype-associated sequence variationin the third variable domain of the human immunodeficiency virus type 1 gp 120 molecule. J Virol. 1992;66:3183-3187.
    • (1992) J Virol , vol.66 , pp. 3183-3187
    • Fouchier, R.A.1    Groenink, M.2    Kootstra, N.N.3
  • 30
    • 0026753639 scopus 로고
    • Evolution of the V3 envelope domain in proviral sequences and isolates of human immunodeficiency virus type 1 during transition of the viral biological phenotype
    • Kuiken CL, de Jong JJ, Baan E, et al. Evolution of the V3 envelope domain in proviral sequences and isolates of human immunodeficiency virus type 1 during transition of the viral biological phenotype. J Virol. 1992;66:5704.
    • (1992) J Virol , vol.66 , pp. 5704
    • Kuiken, C.L.1    De Jong, J.J.2    Baan, E.3
  • 31
    • 0142042463 scopus 로고    scopus 로고
    • Broad NRTI cross-resistance in HIV-1 clinical isolates
    • Whitcomb J, Parkin N, Cheppey C, et al. Broad NRTI cross-resistance in HIV-1 clinical isolates. J Infect Dis. 2003;188:992-1000.
    • (2003) J Infect Dis , vol.188 , pp. 992-1000
    • Whitcomb, J.1    Parkin, N.2    Cheppey, C.3
  • 34
    • 0034523325 scopus 로고    scopus 로고
    • Envelope V3 amino acid sequence predicts HIV-1 phenotype (co-receptor usage and tropism for macrophages) [1]
    • DOI 10.1097/00002030-200012220-00016
    • Briggs DR, Tuttle DL, Sleasman JW, et al. Envelope V3 amino acid sequence predicts HIV-1 phenotype (co-receptor usage and tropism for macrophages). AIDS. 2000;14:2937-2939. (Pubitemid 32042758)
    • (2000) AIDS , vol.14 , Issue.18 , pp. 2937-2939
    • Briggs, D.R.1    Tuttle, D.L.2    Sleasman, J.W.3    Goodenow, M.M.4
  • 35
    • 0026597418 scopus 로고
    • The region of the envelope gene of human immunodeficiency virus type 1 responsible for determination of cell tropism
    • Cann AJ, Churcher MJ, Boyd M, et al. The region of the envelope gene of human immunodeficiency virus type 1 responsible for determination of cell tropism. J Virol. 1992;66:305-309.
    • (1992) J Virol , vol.66 , pp. 305-309
    • Cann, A.J.1    Churcher, M.J.2    Boyd, M.3
  • 39
    • 19344373478 scopus 로고    scopus 로고
    • Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration
    • Kantor R, Katzenstein DA, Effron B, et al. Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: results of a global collaboration. PLoS Med. 2005;2:e112.
    • (2005) PLoS Med , vol.2
    • Kantor, R.1    Katzenstein, D.A.2    Effron, B.3
  • 40
    • 0035984778 scopus 로고    scopus 로고
    • Genetic divergence of human immunodeficiency virus type 1 Ethiopian clade C reverse transcriptase (RT) and rapid development of resistance against nonnucleoside inhibitors of RT
    • DOI 10.1128/AAC.46.7.2087-2094.2002
    • Loemba H, Brenner B, Parniak MA, et al. Genetic divergence of human immunodeficiency virus type 1 Ethiopian clade C reverse transcriptase (RT) and rapid development of resistance against nonnucleoside inhibitors of RT. Antimicrob Agents Chemother. 2002;46:2087-2094. (Pubitemid 34665901)
    • (2002) Antimicrobial Agents and Chemotherapy , vol.46 , Issue.7 , pp. 2087-2094
    • Loemba, H.1    Brenner, B.2    Parniak, M.A.3    Ma'ayan, S.4    Spira, B.5    Moisi, D.6    Oliveira, M.7    Detorio, M.8    Wainberg, M.A.9
  • 41
    • 38349189733 scopus 로고    scopus 로고
    • Impact of antiretroviral therapy on viral tropism in HIV-infected patients followed longitudinally for over 5 years
    • Briz V, Poveda E, del Mar Gonzalez M, et al. Impact of antiretroviral therapy on viral tropism in HIV-infected patients followed longitudinally for over 5 years. J Antimicrob Chemother. 2008;65:405-410.
    • (2008) J Antimicrob Chemother , vol.65 , pp. 405-410
    • Briz, V.1    Poveda, E.2    Del Mar Gonzalez, M.3
  • 42
    • 49849083022 scopus 로고    scopus 로고
    • Chemokine (C-C motif) receptor 5-using envelopes predominate in dual/mixed-tropic HIV from the plasma of drug-naive individuals
    • Irlbeck DM, Amrine-Madsen H, Kitrinos KM, et al. Chemokine (C-C motif) receptor 5-using envelopes predominate in dual/mixed-tropic HIV from the plasma of drug-naive individuals. AIDS. 2008;22: 1425-1431.
    • (2008) AIDS , vol.22 , pp. 1425-1431
    • Irlbeck, D.M.1    Amrine-Madsen, H.2    Kitrinos, K.M.3
  • 43
    • 34548261959 scopus 로고    scopus 로고
    • Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates
    • DOI 10.1097/QAD.0b013e3282ef81ea, PII 0000203020070912000001
    • Low AJ, Dong W, Chan D, et al. Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates. AIDS. 2007;21:F17-F24. (Pubitemid 47329758)
    • (2007) AIDS , vol.21 , Issue.14
    • Low, A.J.1    Dong, W.2    Chan, D.3    Sing, T.4    Swanstrom, R.5    Jensen, M.6    Pillai, S.7    Good, B.8    Harrigan, P.R.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.