Cytotoxicities of alkaloids from processed and unprocessed seeds of Strychnos nux-vomica

Acta Pharmacologica Sinica

Volumn 19, Issue 5, 1998, Pages 425-428

  Cai, Bao Chang ^a   Wang, Tian Shan ^a   Kurokawa, Masahiko ^b   Shlraki, Kimiyasu ^b   Hattori, Masao ^b  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Alkaloids; Cell division; DNA; Immunologic cytotoxicity; Strychnine; Strychnos nux vomica; Thymidine; Vero cells

Indexed keywords

ALKALOID; BRUCINE; NUX VOMICA; STRYCHNINE;

ARTICLE; DNA SYNTHESIS INHIBITION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; GROWTH INHIBITION; IMMUNOCYTOTOXICITY; PLANT SEED; SAND; TRADITIONAL MEDICINE; VERO CELL;

ALKALOIDS; ANGIOSPERMS; ANIMALS; CELL DIVISION; CERCOPITHECUS AETHIOPS; DNA; DRUGS, CHINESE HERBAL; HEAT; STRYCHNINE; TECHNOLOGY, PHARMACEUTICAL; VERO CELLS;

EID: 0031709923     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Cai BC, Nagasawa T, Kadota S, Hattori M, Namba T, Kuraishi Y. Processing of nux vomica. VII. Antinociceptive effects of crude alkaloids from the processed and unprocessed seeds of Strychnos nux-vomica in mice. Biol Pharm Bull 1996; 19: 127-31.
2. Ma C, He YW, Cai BC, Chen L. Toxicity of strychnine, brucine and their N-oxides. J Nanjing Univ Trad Chin Med 1994; 10 (2): 37-9.
3. Cai BC, Wu H, Kadota S, Hattori M, Namba T. Processing of Nux vomica. III. Effects of seven different processings of Nux vomica on chemical constituents and acute toxicity. J Trad Med 1994; 11: 134-41.
4. Cai BC, Hattori M, Namba T. Processing of Nux vomica. II . Changes in alkalod composition of the seeds of Strychnos nux-vomica on traditional drug-processing. Chem Pharm Bull 1990; 38: 1295-8.
5. Cai BC, Yang XW, Kadota S, Hattori M, Namba T. Processing of Nux vomica. I . Four new alkaloids from the processed seeds of Strychnos nux vomica. Shoyakugaku Zasshi 1990; 44: 42-6.
6. 1: its interference with the replication of herpes simplex virus type 1. Antiviral Res 1986; 6: 19-32.