Kinetic modeling sheds light on the mode of action of recombinant factor VIIa on thrombin generation

Thrombosis Research

Volumn 128, Issue 4, 2011, Pages 381-390

  Mitrophanov, Alexander Y ^a   Reifman, Jaques ^a  

^a U S ARMY MEDICAL RESEARCH AND MATERIEL COMMAND   (United States)

Author keywords

Coagulation; Coagulopathy; Computational modeling; rFVIIa; Therapeutic; Thrombin

Indexed keywords

RECOMBINANT BLOOD CLOTTING FACTOR 7A; TISSUE FACTOR PATHWAY INHIBITOR;

ACCURACY; ANTICOAGULATION; ARTICLE; BIOCHEMISTRY; BLOOD CLOTTING TIME; BLOOD SAMPLING; CONTROLLED STUDY; DRUG EFFECT; HEMODILUTION; HEMOPHILIA A; HEMOPHILIA B; HUMAN; PRIORITY JOURNAL; PROTHROMBIN TIME; THROMBIN TIME;

COMPUTER SIMULATION; FACTOR VIIA; HEMOPHILIA A; HEMOPHILIA B; HEMOSTASIS; HEMOSTATICS; HUMANS; KINETICS; LIPOPROTEINS; MODELS, BIOLOGICAL; NUMERICAL ANALYSIS, COMPUTER-ASSISTED; RECOMBINANT PROTEINS; THROMBIN;

EID: 80054923951     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2011.05.013     Document Type: Article

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