Optimizing the early phase development of new analgesics by human pain biomarkers

Expert Review of Neurotherapeutics

Volumn 11, Issue 11, 2011, Pages 1631-1651

  Arendt Nielsen, Lars ^a   Hoeck, Hans Christian ^b  

^a AALBORG UNIVERSITY   (Denmark)

^b CCBR ^*  (Denmark)

Author keywords

analgesics; biomarkers; drug screening; experimental pain; human pain biomarkers; pain assessment; proof of concept; QST; translational pain research

Indexed keywords

ACID; ANALGESIC AGENT; BIOLOGICAL MARKER; BRADYKININ; CAPSAICIN; DODECYL SULFATE SODIUM; GLUTAMIC ACID; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; LACTIC ACID; NERVE GROWTH FACTOR; SEROTONIN; SODIUM CHLORIDE; SUBSTANCE P;

ALGOMETRY; ALLODYNIA; BAROSTAT; DRUG EFFICACY; DRUG MECHANISM; DRUG SCREENING; ELECTROSTIMULATION; HUMAN; HYPERALGESIA; MECHANICAL STIMULATION; MYALGIA; NEUROPATHIC PAIN; PAIN; PAIN ASSESSMENT; PAIN THRESHOLD; REVIEW; STIMULATION; TEMPORAL SUMMATION; THERMAL STIMULATION; ULTRAVIOLET B RADIATION; VISCERAL PAIN;

ANALGESICS; CLINICAL TRIALS AS TOPIC; HUMANS; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; RESEARCH DESIGN;

EID: 80054903539     PISSN: 14737175     EISSN: 17448360     Source Type: Journal    
DOI: 10.1586/ern.11.147     Document Type: Review

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