Changes of Hypertonic Saline-Induced Masseter Muscle Pain Characteristics, by an Infusion of the Serotonin Receptor Type 3 Antagonist Granisetron

Journal of Pain

Volumn 9, Issue 10, 2008, Pages 892-901

  Christidis, Nikolaos ^a   Ioannidou, Kiriaki ^a   Milosevic, Milena ^a   Segerdahl, Märta ^a   Ernberg, Malin ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

5 HT3 receptor; experimental muscle pain; Granisetron; masseter muscle; pain threshold; sex difference

Indexed keywords

GRANISETRON; PLACEBO; SEROTONIN 3 RECEPTOR; SODIUM CHLORIDE;

ADULT; ALLODYNIA; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MASSETER MUSCLE; MYALGIA; MYOFASCIAL PAIN; PAIN ASSESSMENT; PAIN THRESHOLD; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; SINGLE DRUG DOSE;

ADULT; DOUBLE-BLIND METHOD; FACIAL PAIN; FEMALE; GRANISETRON; HUMANS; INJECTIONS, INTRAMUSCULAR; MALE; MASSETER MUSCLE; PAIN MEASUREMENT; PAIN THRESHOLD; RECEPTORS, SEROTONIN, 5-HT3; SALINE SOLUTION, HYPERTONIC; SEROTONIN ANTAGONISTS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 52149088764     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2008.05.002     Document Type: Article

References (48)

1. Arendt-Nielsen L., Curatolo M., and Drewes A. Human experimental pain models in drug development: Translational pain research. Curr Opin Investig Drugs 8 (2007) 41-53
2. Arendt-Nielsen L., Graven-Nielsen T., Svarrer H., and Svensson P. The influence of low back pain on muscle activity and coordination during gait: A clinical and experimental study. Pain 64 (1996) 231-240
3. Babenko V., Graven-Nielsen T., Svensson P., Drewes A.M., Jensen T.S., and Arendt-Nielsen L. Experimental human muscle pain induced by intramuscular injections of bradykinin, serotonin, and substance P. Eur J Pain 3 (1999) 93-102
4. Berkley K.J. Sex differences in pain. Behav Brain Sci 20 (1997) 371-380 discussion 435-513
5. Cairns B.E., Hu J.W., Arendt-Nielsen L., Sessle B.J., and Svensson P. Sex-related differences in human pain and rat afferent discharge evoked by injection of glutamate into the masseter muscle. J Neurophysiol 86 (2001) 782-791
6. Cesare P., and McNaughton P. Peripheral pain mechanisms. Curr Opin Neurobiol 7 (1997) 493-499
7. Christidis N., Nilsson A., Kopp S., and Ernberg M. Intramuscular injection of granisetron into the masseter muscle increases the pressure pain threshold in healthy participants and patients with localized myalgia. Clin J Pain 23 (2007) 467-472
8. Christidis N., Kopp S., and Ernberg M. The effect on mechanical pain threshold over human muscles by oral administration of granisetron and diclofenac-sodium. Pain 113 (2005) 265-270
9. Dworkin S.F., and LeResche L. Research diagnostic criteria for temporomandibular disorders: Review, criteria, examinations and specifications, critique. J Craniomandib Disord 6 (1992) 301-355
10. Ernberg M., Lundeberg T., and Kopp S. Pain and allodynia/hyperalgesia induced by intramuscular injection of serotonin in patients with fibromyalgia and healthy individuals. Pain 85 (2000) 31-39
11. Ernberg M., Lundeberg T., and Kopp S. Effect of propranolol and granisetron on experimentally induced pain and allodynia/hyperalgesia by intramuscular injection of serotonin into the human masseter muscle. Pain 84 (2000) 339-346
12. Ernberg M., Hedenberg-Magnusson B., Alstergren P., and Kopp S. The level of serotonin in the superficial masseter muscle in relation to local pain and allodynia. Life Sci 65 (1999) 313-325
13. Fillingim R.B., and Gear R.W. Sex differences in opioid analgesia: Clinical and experimental findings. Eur J Pain 8 (2004) 413-425
14. Färber L., Stratz T.H., Bruckle W., Späth M., Pongratz D., Lautenschlager J., Kotter I., Zoller B., Peter H.H., Neeck G., Welzel D., Müller W., and German Fibromyalgia Study Group. Short-term treatment of primary fibromyalgia with the 5-HT3-receptor antagonist tropisetron: Results of a randomized, double-blind, placebo-controlled multicenter trial in 418 patients. Int J Clin Pharmacol Res 21 (2001) 1-13
15. Ge H.Y., Madeleine P., and Arendt-Nielsen L. Sex differences in temporal characteristics of descending inhibitory control: An evaluation using repeated bilateral experimental induction of muscle pain. Pain 110 (2004) 72-78
16. Gear R.W., Gordon N.C., Heller P.H., Paul S., Miaskowski C., and Levine J.D. Gender difference in analgesic response to the kappa-opioid pentazocine. Neurosci Lett 205 (1996) 207-209
17. Gerdle B., Lemming D., Kristiansen J., Larsson B., Peolsson M., and Rosendal L. Biochemical alterations in the trapezius muscle of patients with chronic whiplash associated disorders (WAD): A microdialysis study. Eur J Pain 12 (2008) 82-93
18. Graven-Nielsen T., Jansson Y., Segerdahl M., Kristensen J.D., Mense S., Arendt-Nielsen L., and Sollevi A. Experimental pain by ischaemic contractions compared with pain by intramuscular infusions of adenosine and hypertonic saline. Eur J Pain 7 (2003) 93-102
19. Graven-Nielsen T., and Mense S. The peripheral apparatus of muscle pain: Evidence from animal and human studies. Clin J Pain 17 (2001) 2-10
20. Graven-Nielsen T., Babenko V., Svensson P., and Arendt-Nielsen L. Experimentally induced muscle pain induces hypoalgesia in heterotopic deep tissues, but not in homotopic deep tissues. Brain Res 787 (1998) 203-210
21. Graven-Nielsen T., McArdle A., Phoenix J., Arendt-Nielsen L., Jensen T.S., Jackson M.J., and Edwards R.H. In vivo model of muscle pain: Quantification of intramuscular chemical, electrical, and pressure changes associated with saline-induced muscle pain in humans. Pain 69 (1997) 137-143
22. Graven-Nielsen T., Arendt-Nielsen L., Svensson P., and Jensen T.S. Experimental muscle pain: A quantitative study of local and referred pain in humans following injection of hypertonic saline. J Musculoskel Pain 5 (1996) 49-69
23. Guicheney P. Human platelet serotonin content: Methodological aspects and physiological variations. Methods Find Exp Clin Pharmacol 10 (1988) 253-258
24. Hedenberg-Magnusson B., Ernberg M., and Kopp S. Symptoms and signs of temporomandibular disorders in patients with fibromyalgia and local myalgia of the temporomandibular system: A comparative study. Acta Odontol Scand 55 (1997) 344-349
25. Jensen K., and Norup M. Experimental pain in human temporal muscle induced by hypertonic saline, potassium and acidity. Cephalalgia 12 (1992) 101-106
26. Kuryshev Y.A., Brown A.M., Wang L., Benedict C.R., and Rampe D. Interactions of the 5-hydroxytryptamine 3 antagonist class of antiemetic drugs with human cardiac ion channels. J Pharmacol Exp Ther 295 (2000) 614-620
27. Mense S. Nociception from skeletal muscle in relation to clinical muscle pain. Pain 54 (1993) 241-289
28. Muller W., and Stratz T. Local treatment of tendinopathies and myofascial pain syndromes with the 5-HT3 receptor antagonist tropisetron. Scand J Rheumatol Suppl 119 (2004) 44-48
29. 3 receptor antagonist tropisetron in trigger point therapy: A pilot study. J Musculoskel Pain 13 (2005) 43-48
30. Qerama E., Fuglsang-Frederiksen A., Kasch H., Bach F.W., and Jensen T.S. Evoked pain in the motor endplate region of the brachial biceps muscle: An experimental study. Muscle Nerve 29 (2004) 393-400
31. Rollman G.B., and Lautenbacher S. Sex differences in musculoskeletal pain. Clin J Pain 17 (2001) 20-24
32. Rosendal L., Larsson B., Kristiansen J., Peolsson M., Søgaard K., Kjær M., Sørensen J., and Gerdle B. Increase in muscle nociceptive substances and anaerobic metabolism in patients with trapezius myalgia: Microdialysis in rest and during exercise. Pain 112 (2004) 324-334
33. Shah J.P., Phillips T.M., Danoff J.V., and Gerber L.H. An in vivo microanalytical technique for measuring the local biochemical milieu of human skeletal muscle. J Appl Physiol 99 (2005) 1977-1984
34. Sherman J.J., and LeResche L. Does experimental pain response vary across the menstrual cycle?. A methodological review. Am J Physiol Regul Integr Comp Physiol 291 (2006) R245-R256
35. Siegel S., and Castellan N. Nonparametric Statistics for the Behavioral Sciences. 2nd edition (1988), McGraw-Hill International Editions, New York, NY
36. Stohler C.S., and Lund J.P. Effects of noxious stimulation of the jaw muscles on the sensory experience of volunteer human subjects. In: Stohler C.S., and Carlson D.S. (Eds). Biological and Psychological Aspects of Orofacial Pain (1994), The University of Michigan Center for Human Growth and Development, Ann Arbor, MI 55-73
37. Stratz T., and Müller W. Treatment of chronic low back pain with tropisetron. Scand J Rheumatol Suppl 119 (2004) 76-78
38. Sung D., Dong X., Ernberg M., Kumar U., and Cairns B.E. Serotonin (5-HT) excites rat masticatory muscle afferent fibers through activation of peripheral 5-HT3 receptors. Pain 134 (2008) 41-50
39. Svensson P., Bak J., and Troest T. Spread and referral of experimental pain in different jaw muscles. J Orofac Pain 17 (2003) 214-223
40. Svensson P., Cairns B.E., Wang K., Hu J.W., Graven-Nielsen T., Arendt-Nielsen L., and Sessle B.J. Glutamate-evoked pain and mechanical allodynia in the human masseter muscle. Pain 101 (2003) 221-227
41. Svensson P., Wang K., and Arendt-Nielsen L. Effect of muscle relaxants on experimental jaw-muscle pain and jaw-stretch reflexes: A double-blind and placebo-controlled trial. Eur J Pain 7 (2003) 449-456
42. Svensson P., and Graven-Nielsen T. Craniofacial muscle pain: Review of mechanisms and clinical manifestations. J Orofac Pain 15 (2001) 117-145
43. Tabona M.V. An overview on the use of granisetron in the treatment of emesis associated with cytostatic chemotherapy. Eur J Cancer 26 Suppl 1 (1990) S37-S44
44. Tegeder L., Zimmermann J., Meller S.T., and Geisslinger G. Release of algesic substances in human experimental muscle pain. Inflamm Res 51 (2002) 393-402
45. Warren M.P., and Fried J.L. Temporomandibular disorders and hormones in women. Cells Tissues Organs 169 (2001) 187-192
46. Vecchiet L., Dragani L., Bigontina P., Obletter G., and Giamberardino M.A. Experimental referred pain and hyperalgesia from muscles in humans. In: Vecchiet L., Albe-Fessard D., and Lindblom U. (Eds). New Trends in Referred Pain and Hyperalgesia (1993), Elsevier, Amsterdam, the Netherlands 239-249
47. Ye J.H., Mui W.C., Ren J., Hunt T.E., Wu W.H., and Zbuzek V.K. Ondansetron exhibits the properties of a local anesthetic. Anesth Analg 85 (1997) 1116-1121
48. Zeitz K.P., Guy N., Malmberg A.B., Dirajlal S., Martin W.J., Sun L., Bonhaus D.W., Stucky C.L., Julius D., and Basbaum A.I. The 5-HT3 subtype of serotonin receptor contributes to nociceptive processing via a novel subset of myelinated and unmyelinated nociceptors. J Neurosci 22 (2002) 1010-1019