The Sunburn Pain Model: The Stability of Primary and Secondary Hyperalgesia over 10 Hours in a Crossover Setting

Anesthesia and Analgesia

Volumn 98, Issue 1, 2004, Pages 173-177

  Gustorff, Burkhard ^a   Anzenhofer, Sebastian ^a   Sycha, Thomas ^a   Lehr, Stephan ^a   Kress, Hans G ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; ELECTROSTIMULATION; FEMALE; HUMAN; HUMAN EXPERIMENT; HYPERALGESIA; MEASUREMENT; NORMAL HUMAN; PAIN; PAIN ASSESSMENT; PAIN THRESHOLD; PRICK TEST; PRIORITY JOURNAL; SKIN SENSITIVITY; SUNBURN; ULTRAVIOLET B RADIATION;

EID: 0346733078     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ANE.0000093224.77281.A5     Document Type: Article

References (15)

1. Sycha T, Gustorff B, Lehr S, et al. Evaluation of an inflammatory pain model for non-steroidal anti-inflammatory drugs. Br J Clin Pharmacol 2003;56:165-72.
2. Hoffmann RT, Schmelz M. Time course of UVA- and UVB-induced inflammation and hyperalgesia in human skin. Eur J Pain 1999;3:131-9.
3. Benrath J, Gillardon F, Zimmermann M. Differential time courses of skin blood flow and hyperalgesia in the human sunburn reaction following ultraviolet irradiation of the skin. Eur J Pain 2001;5:155-67.
4. Gustorff B, Sycha T, Anzenhofer S, et al. Only high dose rofecoxib reduces secondary hyperalgesia in an inflammatory pain model in volunteers. Eur J Anaesthesiol 2001; Abstract-Supplement, P-18, 23rd Meeting of the European Academy of Anaesthesiology, Graz, Austria.
5. Yarnitsky D, Sprecher E, Zaslansky R, Hemli JA. Heat pain thresholds: normative data and repeatability. Pain 1995;60:329-32.
6. Yarnitsky D, Sprecher E, Zaslansky R, Hemli JA. Multiple session experimental pain measurement. Pain 1996;67:327-33.
7. McCleskey EW, Gold MS. Ion channels of nociception. Annu Rev Physiol 1999;61:835-56.
8. Koppert W, Ostermeier N, Sittl R, et al. Low-dose lidocaine reduces secondary hyperalgesia by a central mode of action. Pain 2000;85:217-24.
9. Petersen KL, Rowbotham MC. A new human experimental pain model: the heat/capsaicin sensitization model. Neuroreport 1999;10:1511-6.
10. Koppert W, Dern SK, Sittl R, et al. A new model of electrically evoked pain and hyperalgesia in human skin: the effects of intravenous alfentanil, S(+)-ketamine, and lidocaine. Anesthesiology 2001;95:395-402.
11. Pedersen JL, Kehlet H. Hyperalgesia in a human model of acute inflammatory pain: a methodological study. Pain 1998;74:139-51.
12. Moiniche S, Dahl JB, Kehlet H. Time course of primary and secondary hyperalgesia after heat injury to the skin. Br J Anaesth 1993;71:201-5.
13. Dirks J, Petersen KL, Rowbotham MC, Dahl JB. Gabapentin suppresses cutaneous hyperalgesia following heat-capsaicin sensitization. Anesthesiology 2002;97:102-7.
14. Gustorff B, Nahlik G, Hoerauf KH, Kress HG. The absence of acute tolerance during remifentanil infusion in volunteers. Anesth Analg 2002;94:1223-8.
15. Brennum J, Dahl JB, Moiniche S, Arendt-Nielsen L. Quantitative sensory examination of epidural anaesthesia and analgesia in man: effects of pre- and post-traumatic morphine on hyperalgesia. Pain 1994;59:261-71.