-
1
-
-
56549104692
-
Retinal degeneration triggered by inactivation of PTEN in the retinal pigment epithelium
-
Kim J.W., Kang K.H., Burrola P., Mak T.W., Lemke G. Retinal degeneration triggered by inactivation of PTEN in the retinal pigment epithelium. Genes Dev. 2008, 22:3147-3157.
-
(2008)
Genes Dev.
, vol.22
, pp. 3147-3157
-
-
Kim, J.W.1
Kang, K.H.2
Burrola, P.3
Mak, T.W.4
Lemke, G.5
-
2
-
-
11144273817
-
Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration
-
Wenzel A., Grimm C., Samardzija M., Reme C.E. Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration. Prog. Retin. Eye Res. 2005, 24:275-306.
-
(2005)
Prog. Retin. Eye Res.
, vol.24
, pp. 275-306
-
-
Wenzel, A.1
Grimm, C.2
Samardzija, M.3
Reme, C.E.4
-
3
-
-
0033520640
-
Oxidative damage and age-related macular degeneration
-
Winkler B.S., Boulton M.E., Gottsch J.D., Sternberg P. Oxidative damage and age-related macular degeneration. Mol. Vis. 1999, 5:32.
-
(1999)
Mol. Vis.
, vol.5
, pp. 32
-
-
Winkler, B.S.1
Boulton, M.E.2
Gottsch, J.D.3
Sternberg, P.4
-
4
-
-
0034960793
-
The role of the retinal pigment epithelium: topographical variation and ageing changes
-
Boulton M., Dayhaw-Barker P. The role of the retinal pigment epithelium: topographical variation and ageing changes. Eye 2001, 15:384-389.
-
(2001)
Eye
, vol.15
, pp. 384-389
-
-
Boulton, M.1
Dayhaw-Barker, P.2
-
5
-
-
0031761418
-
Morphogenesis of the retinal pigment epithelium: toward understanding retinal degenerative diseases
-
Marmorstein A.D., Finnemann S.C., Bonilha V.L., Rodriguez-Boulan E. Morphogenesis of the retinal pigment epithelium: toward understanding retinal degenerative diseases. Ann. NY Acad. Sci. 1998, 857:1-12.
-
(1998)
Ann. NY Acad. Sci.
, vol.857
, pp. 1-12
-
-
Marmorstein, A.D.1
Finnemann, S.C.2
Bonilha, V.L.3
Rodriguez-Boulan, E.4
-
6
-
-
0042357381
-
Progress toward understanding the genetic and biochemical mechanisms of inherited photoreceptor degenerations
-
Pacione L.R., Szego M.J., Ikeda S., Nishina P.M., McInnes R.R. Progress toward understanding the genetic and biochemical mechanisms of inherited photoreceptor degenerations. Annu. Rev. Neurosci. 2003, 26:657-700.
-
(2003)
Annu. Rev. Neurosci.
, vol.26
, pp. 657-700
-
-
Pacione, L.R.1
Szego, M.J.2
Ikeda, S.3
Nishina, P.M.4
McInnes, R.R.5
-
7
-
-
1842478123
-
Current concepts in the pathogenesis of age-related macular degeneration
-
Zarbin M.A. Current concepts in the pathogenesis of age-related macular degeneration. Arch. Ophthalmol. 2004, 122:598-614.
-
(2004)
Arch. Ophthalmol.
, vol.122
, pp. 598-614
-
-
Zarbin, M.A.1
-
8
-
-
0033991466
-
Oxidative damage and protection of the RPE
-
Cai J., Nelson K.C., Wu M., Sternberg P., Jones D.P. Oxidative damage and protection of the RPE. Prog. Retin. Eye Res. 2000, 19:205-221.
-
(2000)
Prog. Retin. Eye Res.
, vol.19
, pp. 205-221
-
-
Cai, J.1
Nelson, K.C.2
Wu, M.3
Sternberg, P.4
Jones, D.P.5
-
9
-
-
18044366931
-
RPE lipofuscin and its role in retinal pathobiology
-
Sparrow J.R., Boulton M. RPE lipofuscin and its role in retinal pathobiology. Exp. Eye Res. 2005, 80:595-606.
-
(2005)
Exp. Eye Res.
, vol.80
, pp. 595-606
-
-
Sparrow, J.R.1
Boulton, M.2
-
10
-
-
0034671726
-
Age-related macular degeneration. The lipofusion component N-retinyl-N-retinylidene ethanolamine detaches proapoptotic proteins from mitochondria and induces apoptosis in mammalian retinal pigment epithelial cells
-
Suter M., Reme C., Grimm C., Wenzel A., Jaattela M., Esser P., Kociok N., Leist M., Richter C. Age-related macular degeneration. The lipofusion component N-retinyl-N-retinylidene ethanolamine detaches proapoptotic proteins from mitochondria and induces apoptosis in mammalian retinal pigment epithelial cells. J. Biol. Chem. 2000, 275:39625-39630.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 39625-39630
-
-
Suter, M.1
Reme, C.2
Grimm, C.3
Wenzel, A.4
Jaattela, M.5
Esser, P.6
Kociok, N.7
Leist, M.8
Richter, C.9
-
11
-
-
65549150446
-
The PI3K-PTEN tug-of-war, oxidative stress and retinal degeneration
-
Kang K.H., Lemke G., Kim J.W. The PI3K-PTEN tug-of-war, oxidative stress and retinal degeneration. Trends Mol. Med. 2009, 15:191-198.
-
(2009)
Trends Mol. Med.
, vol.15
, pp. 191-198
-
-
Kang, K.H.1
Lemke, G.2
Kim, J.W.3
-
12
-
-
33947383078
-
Changes in select redox proteins of the retinal pigment epithelium in age-related macular degeneration
-
Decanini A., Nordgaard C.L., Feng X., Ferrington D.A., Olsen T.W. Changes in select redox proteins of the retinal pigment epithelium in age-related macular degeneration. Am. J. Ophthalmol. 2007, 143:607-615.
-
(2007)
Am. J. Ophthalmol.
, vol.143
, pp. 607-615
-
-
Decanini, A.1
Nordgaard, C.L.2
Feng, X.3
Ferrington, D.A.4
Olsen, T.W.5
-
13
-
-
78650928867
-
MTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice
-
Zhao C., Yasumura D., Li X., Matthes M., Lloyd M., Nielsen G., Ahern K., Snyder M., Bok D., Dunaief J.L., LaVail M.M., Vollrath D. MTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice. J. Clin. Invest. 2011, 121:369-383.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 369-383
-
-
Zhao, C.1
Yasumura, D.2
Li, X.3
Matthes, M.4
Lloyd, M.5
Nielsen, G.6
Ahern, K.7
Snyder, M.8
Bok, D.9
Dunaief, J.L.10
LaVail, M.M.11
Vollrath, D.12
-
14
-
-
0030765276
-
Polarity and the development of the outer blood-retinal barrier
-
Rizzolo L.J. Polarity and the development of the outer blood-retinal barrier. Histol. Histopathol. 1997, 12:1057-1067.
-
(1997)
Histol. Histopathol.
, vol.12
, pp. 1057-1067
-
-
Rizzolo, L.J.1
-
15
-
-
33748328059
-
The other pigment cell: specification and development of the pigmented epithelium of the vertebrate eye
-
Bharti K., Nguyen M.T., Skuntz S., Bertuzzi S., Arnheiter H. The other pigment cell: specification and development of the pigmented epithelium of the vertebrate eye. Pigment Cell Res. 2006, 19:380-394.
-
(2006)
Pigment Cell Res.
, vol.19
, pp. 380-394
-
-
Bharti, K.1
Nguyen, M.T.2
Skuntz, S.3
Bertuzzi, S.4
Arnheiter, H.5
-
16
-
-
0033946740
-
Phosphorylation of the PTEN tail regulates protein stability and function
-
Vazquez F., Ramaswamy S., Nakamura N., Sellers W.R. Phosphorylation of the PTEN tail regulates protein stability and function. Mol. Cell. Biol. 2000, 20:5010-5018.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 5010-5018
-
-
Vazquez, F.1
Ramaswamy, S.2
Nakamura, N.3
Sellers, W.R.4
-
17
-
-
0344676389
-
An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice
-
Ambati J., Anand A., Fernandez S., Sakurai E., Lynn B.C., Kuziel W.A., Rollins B.J., Ambati B.K. An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice. Nat. Med. 2003, 9:1390-1397.
-
(2003)
Nat. Med.
, vol.9
, pp. 1390-1397
-
-
Ambati, J.1
Anand, A.2
Fernandez, S.3
Sakurai, E.4
Lynn, B.C.5
Kuziel, W.A.6
Rollins, B.J.7
Ambati, B.K.8
-
18
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3, 4, 5-trisphosphate
-
Maehama T., Dixon J.E. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3, 4, 5-trisphosphate. J. Biol. Chem. 1998, 273:13375-13378.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
19
-
-
0029804116
-
Mechanism of activation of protein kinase B by insulin and IGF-1
-
Alessi D.R., Andjelkovic M., Caudwell B., Cron P., Morrice N., Cohen P., Hemmings B.A. Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J. 1996, 15:6541-6551.
-
(1996)
EMBO J.
, vol.15
, pp. 6541-6551
-
-
Alessi, D.R.1
Andjelkovic, M.2
Caudwell, B.3
Cron, P.4
Morrice, N.5
Cohen, P.6
Hemmings, B.A.7
-
20
-
-
33746628449
-
Drusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice. a model of age-related macular degeneration
-
Imamura Y., Noda S., Hashizume K., Shinoda K., Yamaguchi M., Uchiyama S., Shimizu T., Mizushima Y., Shirasawa T., Tsubota K. Drusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice. a model of age-related macular degeneration. Proc. Natl. Acad. Sci. USA 2006, 103:11282-11287.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 11282-11287
-
-
Imamura, Y.1
Noda, S.2
Hashizume, K.3
Shinoda, K.4
Yamaguchi, M.5
Uchiyama, S.6
Shimizu, T.7
Mizushima, Y.8
Shirasawa, T.9
Tsubota, K.10
-
21
-
-
0034848719
-
Ocular pathology in mitochondrial superoxide dismutase (Sod2)-deficient mice
-
Sandbach J.M., Coscun P.E., Grossniklaus H.E., Kokoszka J.E., Newman N.J., Wallace D.C. Ocular pathology in mitochondrial superoxide dismutase (Sod2)-deficient mice. Invest. Ophthalmol. Vis. Sci. 2001, 42:2173-2178.
-
(2001)
Invest. Ophthalmol. Vis. Sci.
, vol.42
, pp. 2173-2178
-
-
Sandbach, J.M.1
Coscun, P.E.2
Grossniklaus, H.E.3
Kokoszka, J.E.4
Newman, N.J.5
Wallace, D.C.6
-
22
-
-
33751354767
-
MCP-1/CCR2 signalling pathway regulates hyperoxia-induced acute lung injury via nitric oxide production
-
Okuma T., Terasaki Y., Sakashita N., Kaikita K., Kobayashi H., Hayasaki T., Kuziel W.A., Baba H., Takeya M. MCP-1/CCR2 signalling pathway regulates hyperoxia-induced acute lung injury via nitric oxide production. Int. J. Exp. Pathol. 2006, 87:475-483.
-
(2006)
Int. J. Exp. Pathol.
, vol.87
, pp. 475-483
-
-
Okuma, T.1
Terasaki, Y.2
Sakashita, N.3
Kaikita, K.4
Kobayashi, H.5
Hayasaki, T.6
Kuziel, W.A.7
Baba, H.8
Takeya, M.9
-
23
-
-
31344445962
-
Behavioral and anatomical abnormalities in a sodium iodate-induced model of retinal pigment epithelium degeneration
-
Enzmann V., Row B.W., Yamauchi Y., Kheirandish L., Gozal D., Kaplan H.J., McCall M.A. Behavioral and anatomical abnormalities in a sodium iodate-induced model of retinal pigment epithelium degeneration. Exp. Eye Res. 2006, 82:441-448.
-
(2006)
Exp. Eye Res.
, vol.82
, pp. 441-448
-
-
Enzmann, V.1
Row, B.W.2
Yamauchi, Y.3
Kheirandish, L.4
Gozal, D.5
Kaplan, H.J.6
McCall, M.A.7
-
24
-
-
0037972476
-
Morphologic characteristics of retinal degeneration induced by sodium iodate in mice
-
Kiuchi K., Yoshizawa K., Shikata N., Moriguchi K., Tsubura A. Morphologic characteristics of retinal degeneration induced by sodium iodate in mice. Curr. Eye Res. 2002, 25:373-379.
-
(2002)
Curr. Eye Res.
, vol.25
, pp. 373-379
-
-
Kiuchi, K.1
Yoshizawa, K.2
Shikata, N.3
Moriguchi, K.4
Tsubura, A.5
-
25
-
-
0019456760
-
Transient breakdown of the retinal pigment epithelium diffusion barrier after sodium iodate: a fluorescein angiographic and morphological study in the rabbit
-
Ringvold A., Olsen E.G., Flage T. Transient breakdown of the retinal pigment epithelium diffusion barrier after sodium iodate: a fluorescein angiographic and morphological study in the rabbit. Exp. Eye Res. 1981, 33:361-369.
-
(1981)
Exp. Eye Res.
, vol.33
, pp. 361-369
-
-
Ringvold, A.1
Olsen, E.G.2
Flage, T.3
-
26
-
-
0035394373
-
Regulation of PTEN binding to MAGI-2 by two putative phosphorylation sites at threonine 382 and 383
-
Tolkacheva T., Boddapati M., Sanfiz A., Tsuchida K., Kimmelman A.C., Chan A.M. Regulation of PTEN binding to MAGI-2 by two putative phosphorylation sites at threonine 382 and 383. Cancer Res. 2001, 61:4985-4989.
-
(2001)
Cancer Res.
, vol.61
, pp. 4985-4989
-
-
Tolkacheva, T.1
Boddapati, M.2
Sanfiz, A.3
Tsuchida, K.4
Kimmelman, A.C.5
Chan, A.M.6
-
29
-
-
20844448882
-
Activation of the PI3K/mTOR pathway by BCR-ABL contributes to increased production of reactive oxygen species
-
Kim J.H., Chu S.C., Gramlich J.L., Pride Y.B., Babendreier E., Chauhan D., Salgia R., Podar K., Griffin J.D., Sattler M. Activation of the PI3K/mTOR pathway by BCR-ABL contributes to increased production of reactive oxygen species. Blood 2005, 105:1717-1723.
-
(2005)
Blood
, vol.105
, pp. 1717-1723
-
-
Kim, J.H.1
Chu, S.C.2
Gramlich, J.L.3
Pride, Y.B.4
Babendreier, E.5
Chauhan, D.6
Salgia, R.7
Podar, K.8
Griffin, J.D.9
Sattler, M.10
-
30
-
-
42249110548
-
Suppressing PTEN activity by tobacco smoke plus interleukin-1beta modulates dissociation of VE-cadherin/beta-catenin complexes in endothelium
-
Barbieri S.S., Ruggiero L., Tremoli E., Weksler B.B. Suppressing PTEN activity by tobacco smoke plus interleukin-1beta modulates dissociation of VE-cadherin/beta-catenin complexes in endothelium. Arterioscler. Thromb. Vasc. Biol. 2008, 28:732-738.
-
(2008)
Arterioscler. Thromb. Vasc. Biol.
, vol.28
, pp. 732-738
-
-
Barbieri, S.S.1
Ruggiero, L.2
Tremoli, E.3
Weksler, B.B.4
-
31
-
-
33750915802
-
Regulation of signal transduction through protein cysteine oxidation
-
Cross J.V., Templeton D.J. Regulation of signal transduction through protein cysteine oxidation. Antioxid. Redox Signal. 2006, 8:1819-1827.
-
(2006)
Antioxid. Redox Signal.
, vol.8
, pp. 1819-1827
-
-
Cross, J.V.1
Templeton, D.J.2
-
32
-
-
15044362438
-
Intracellular messenger function of hydrogen peroxide and its regulation by peroxiredoxins
-
Rhee S.G., Kang S.W., Jeong W., Chang T.S., Yang K.S., Woo H.A. Intracellular messenger function of hydrogen peroxide and its regulation by peroxiredoxins. Curr. Opin. Cell Biol. 2005, 17:183-189.
-
(2005)
Curr. Opin. Cell Biol.
, vol.17
, pp. 183-189
-
-
Rhee, S.G.1
Kang, S.W.2
Jeong, W.3
Chang, T.S.4
Yang, K.S.5
Woo, H.A.6
-
33
-
-
0036193746
-
Oxidants painting the cysteine chapel: redox regulation of PTPs
-
Xu D., Rovira I.I., Finkel T. Oxidants painting the cysteine chapel: redox regulation of PTPs. Dev. Cell 2002, 2:251-252.
-
(2002)
Dev. Cell
, vol.2
, pp. 251-252
-
-
Xu, D.1
Rovira, I.I.2
Finkel, T.3
-
34
-
-
49849102642
-
Role of inflammation in the development of renal damage and dysfunction in angiotensin II-induced hypertension
-
Liao T.D., Yang X.P., Liu Y.H., Shesely E.G., Cavasin M.A., Kuziel W.A., Pagano P.J., Carretero O.A. Role of inflammation in the development of renal damage and dysfunction in angiotensin II-induced hypertension. Hypertension 2008, 52:256-263.
-
(2008)
Hypertension
, vol.52
, pp. 256-263
-
-
Liao, T.D.1
Yang, X.P.2
Liu, Y.H.3
Shesely, E.G.4
Cavasin, M.A.5
Kuziel, W.A.6
Pagano, P.J.7
Carretero, O.A.8
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