Multivoxel proton MR spectroscopy used to distinguish anterior cingulate metabolic abnormalities in patients with schizophrenia

Radiology

Volumn 261, Issue 2, 2011, Pages 542-550

  Hardy, Caitlin J ^a   Tal, Assaf ^a   Babb, James S ^a   Perry, Nissa N ^a   Messinger, Julie W ^a,b   Antonius, Daniel ^a,b   Malaspina, Dolores ^a,b   Gonen, Oded ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Institute for Social and Psychiatric Initiatives   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE; CREATINE; N ACETYLASPARTIC ACID;

ADULT; ANTERIOR CINGULATE; ARTICLE; BRAIN METABOLISM; BRAIN REGION; CAUDAL REGION; CLINICAL ARTICLE; CLINICAL TRIAL; FEMALE; HUMAN; MALE; METABOLITE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTON NUCLEAR MAGNETIC RESONANCE; RECEIVER OPERATING CHARACTERISTIC; ROSTRAL REGION; SCHIZOPHRENIA; SENSITIVITY AND SPECIFICITY; THREE DIMENSIONAL IMAGING;

ADULT; ASPARTIC ACID; CASE-CONTROL STUDIES; CHOLINE; CREATINE; FEMALE; GYRUS CINGULI; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; MAGNETIC RESONANCE SPECTROSCOPY; MALE; PROTONS; SCHIZOPHRENIA; SENSITIVITY AND SPECIFICITY;

EID: 80054778595     PISSN: 00338419     EISSN: 15271315     Source Type: Journal    
DOI: 10.1148/radiol.11110675     Document Type: Article

References (49)

1. Mueser KT, Penn DL. Meta-analysis examining the effects of social skills training on schizophrenia. Psychol Med 2004;34(7): 1365-1367.
2. Wu EQ, Birnbaum HG, Shi L, et al. The economic burden of schizophrenia in the United States in 2002. J Clin Psychiatry 2005;66(9):1122-1129. (Pubitemid 41442278)
3. Kraepelin E. Dementia praecox and paraphrenia. Huntington, NY : Krieger, 1971.
4. Tamminga CA, Buchanan RW, Gold JM. The role of negative symptoms and cognitive dysfunction in schizophrenia outcome. Int Clin Psychopharmacol 1998;13(Suppl 3): S21-S26. (Pubitemid 28282866)
5. Messinger JW, Trémeau F, Antonius D, et al. Avolition and expressive deficits capture negative symptom phenomenology: implications for DSM-5 and schizophrenia research. Clin Psychol Rev 2011;31(1):161-168.
6. Fornito A, Yücel M, Dean B, Wood SJ, Pantelis C. Anatomical abnormalities of the anterior cingulate cortex in schizophrenia: bridging the gap between neuroimaging and neuropathology. Schizophr Bull 2009; 35(5):973-993.
7. Bush G, Luu P, Posner MI. Cognitive and emotional influences in anterior cingulate cortex. Trends Cogn Sci 2000;4(6):215-222. (Pubitemid 30332147)
8. Baiano M, David A, Versace A, Churchill R, Balestrieri M, Brambilla P. Anterior cingulate volumes in schizophrenia: a systematic review and a meta-analysis of MRI studies. Schizophr Res 2007;93(1-3):1-12. (Pubitemid 46817932)
9. Preuss UW, Zetzsche T, Pogarell O, et al. Anterior cingulum volumetry, auditory P300 in schizophrenia with negative symptoms. Psychiatry Res 2010;183(2):133-139.
10. Choi JS, Kang DH, Kim JJ, et al. Decreased caudal anterior cingulate gyrus volume and positive symptoms in schizophrenia. Psychiatry Res 2005;139(3):239-247.
11. Taylor SF, Chen AC, Tso IF, Liberzon I, Welsh RC. Social appraisal in chronic psychosis: role of medial frontal and occipital networks. J Psychiatr Res 2011;45(4): 526-538.
12. Habel U, Chechko N, Pauly K, et al. Neural correlates of emotion recognition in schizophrenia . Schizophr Res 2010;122(1-3): 113-123.
13. Wilmsmeier A, Ohrmann P, Suslow T, et al. Neural correlates of set-shifting: decomposing executive functions in schizophrenia. J Psychiatry Neurosci 2010;35(5):321-329.
14. Abbott C, Bustillo J. What have we learned from proton magnetic resonance spectroscopy about schizophrenia? a critical update. Curr Opin Psychiatry 2006;19(2):135-139. (Pubitemid 44406123)
15. Gujar SK, Maheshwari S, Björkman- Burtscher I, Sundgren PC. Magnetic resonance spectroscopy. J Neuroophthalmol 2005; 25(3):217-226.
16. Ross B, Bluml S. Magnetic resonance spectroscopy of the human brain. Anat Rec 2001; 265(2):54-84.
17. Deicken RF, Zhou L, Schuff N, Weiner MW. Proton magnetic resonance spectroscopy of the anterior cingulate region in schizophrenia . Schizophr Res 1997;27(1):65-71. (Pubitemid 27465724)
18. Bustillo JR, Rowland LM, Mullins P, et al. 1H-MRS at 4 tesla in minimally treated early schizophrenia. Mol Psychiatry 2010;15(6): 629-636.
19. Premkumar P, Parbhakar VA, Fannon D, et al. N-acetyl aspartate concentration in the anterior cingulate cortex in patients with schizophrenia: a study of clinical and neuropsychological correlates and preliminary exploration of cognitive behaviour therapy effects. Psychiatry Res 2010;182(3):251-260.
20. Ohrmann P, Kugel H, Bauer J, et al. Learning potential on the WCST in schizophrenia is related to the neuronal integrity of the anterior cingulate cortex as measured by proton magnetic resonance spectroscopy. Schizophr Res 2008;106(2-3):156-163.
21. Kreis R. Issues of spectral quality in clinical 1H-magnetic resonance spectroscopy and a gallery of artifacts. NMR Biomed 2004; 17(6):361-381. (Pubitemid 39335175)
22. Nurnberger JI Jr, Blehar MC, Kaufmann CA, et al. Diagnostic interview for genetic studies: rationale, unique features, and training- NIMH Genetics Initiative. Arch Gen Psychiatry 1994;51(11):849-859;discussion 863-864.
23. Hu J, Javaid T, Arias-Mendoza F, Liu Z, McNamara R, Brown TR. A fast, reliable, automatic shimming procedure using 1H chemical-shift-imaging spectroscopy. J Magn Reson B 1995;108(3):213-219.
24. Goelman G, Liu S, Hess D, Gonen O. Optimizing the efficiency of high-field multivoxel spectroscopic imaging by multiplexing in space and time. Magn Reson Med 2006;56(1):34-40.
25. Goelman G, Liu S, Fleysher R, Fleysher L, Grossman RI, Gonen O. Chemical-shift artifact reduction in Hadamard-encoded MR spectroscopic imaging at high (3T and 7T) magnetic fields. Magn Reson Med 2007; 58(1):167-173. (Pubitemid 47229929)
26. Li BS, Regal J, Gonen O. SNR versus resolution in 3D 1H MRS of the human brain at high magnetic fields. Magn Reson Med 2001;46(6):1049-1053. (Pubitemid 33104290)
27. Li S, Dardzinski BJ, Collins CM, Yang QX, Smith MB. Three-dimensional mapping of the static magnetic field inside the human head. Magn Reson Med 1996;36(5):705-714. (Pubitemid 26376709)
28. Mareci TH, Brooker HR. Essential considerations for spectral localization using indirect gradient encoding of spatial information. J Magn Reson 1991;92(2):229-246.
29. Brooker HR, Mareci TH, Mao JT. Selective Fourier transform localization. Magn Reson Med 1987;5(5):417-433. (Pubitemid 17167631)
30. Goelman G, Liu S, Gonen O. Reducing voxel bleed in Hadamard-encoded MRI and MRS. Magn Reson Med 2006;55(6):1460-1465. (Pubitemid 43856785)
31. Marion D, Ikura M, Bax A. Improved solvent suppression in one- and two-dimensional NMR spectra by convolution of time domain data. J Magn Reson 1989;84(2):425-430.
32. Gonen O, Murdoch JB, Stoyanova R, Goelman G. 3D multivoxel proton spectroscopy of human brain using a hybrid of 8th-order Hadamard encoding with 2D chemical shift imaging. Magn Reson Med 1998;39(1):34-40. (Pubitemid 28028336)
33. Ashburner J, Friston K. Multimodal image coregistration and partitioning: a unified framework. Neuroimage 1997;6(3):209-217. (Pubitemid 27488452)
34. Ashburner J, Friston KJ. Voxel-based morphometry: the methods. Neuroimage 2000; 11(6 Pt 1):805-821.
35. Soher BJ, Young K, Govindaraju V, Maudsley AA. Automated spectral analysis III: application to in vivo proton MR spectroscopy and spectroscopic imaging. Magn Reson Med 1998;40(6):822-831. (Pubitemid 28543833)
36. Inglese M, Li BS, Rusinek H, Babb JS, Grossman RI, Gonen O. Diffusely elevated cerebral choline and creatine in relapsingremitting multiple sclerosis. Magn Reson Med 2003;50(1):190-195. (Pubitemid 36841875)
37. Träber F, Block W, Lamerichs R, Gieseke J, Schild HH. 1H metabolite relaxation times at 3.0 tesla: measurements of T1 and T2 values in normal brain and determination of regional differences in transverse relaxation . J Magn Reson Imaging 2004;19(5): 537-545. (Pubitemid 38619915)
38. Kirov II, Fleysher L, Fleysher R, Patil V, Liu S, Gonen O. Age dependence of regional proton metabolites T2 relaxation times in the human brain at 3 T. Magn Reson Med 2008; 60(4):790-795.
39. Posse S, Otazo R, Caprihan A, et al. Proton echo-planar spectroscopic imaging of J-coupled resonances in human brain at 3 and 4 Tesla. Magn Reson Med 2007; 58(2):236-244. (Pubitemid 47267640)
40. Todtenkopf MS, Vincent SL, Benes FM. A cross-study meta-analysis and threedimensional comparison of cell counting in the anterior cingulate cortex of schizophrenic and bipolar brain. Schizophr Res 2005;73(1):79-89. (Pubitemid 39574682)
41. Bouras C, Kövari E, Hof PR, Riederer BM, Giannakopoulos P. Anterior cingulate cortex pathology in schizophrenia and bipolar disorder. Acta Neuropathol (Berl) 2001; 102(4):373-379. (Pubitemid 32894708)
42. Cotter D, Mackay D, Landau S, Kerwin R, Everall I. Reduced glial cell density and neuronal size in the anterior cingulate cortex in major depressive disorder. Arch Gen Psychiatry 2001;58(6):545-553. (Pubitemid 32523734)
43. Chana G, Landau S, Beasley C, Everall IP, Cotter D. Two-dimensional assessment of cytoarchitecture in the anterior cingulate cortex in major depressive disorder, bipolar disorder, and schizophrenia: evidence for decreased neuronal somal size and increased neuronal density. Biol Psychiatry 2003;53(12):1086-1098. (Pubitemid 36695084)
44. Kane JM, Correll CU. Past and present progress in the pharmacologic treatment of schizophrenia. J Clin Psychiatry 2010; 71(9):1115-1124.
45. Mikkelsen JD, Thomsen MS, Hansen HH, Lichota J. Use of biomarkers in the discovery of novel anti-schizophrenia drugs. Drug Discov Today 2010;15(3-4):137-141.
46. Wood SJ, Yücel M, Wellard RM, et al. Evidence for neuronal dysfunction in the anterior cingulate of patients with schizophrenia: a proton magnetic resonance spectroscopy study at 3 T. Schizophr Res 2007; 94(1-3):328-331. (Pubitemid 47039293)
47. Ende G, Braus DF, Walter S, et al. Effects of age, medication, and illness duration on the N-acetyl aspartate signal of the anterior cingulate region in schizophrenia. Schizophr Res 2000;41(3):389-395. (Pubitemid 30109595)
48. Ongür D, Prescot AP, Jensen JE, Cohen BM, Renshaw PF. Creatine abnormalities in schizophrenia and bipolar disorder. Psychiatry Res 2009;172(1):44-48.
49. Tayoshi S, Sumitani S, Taniguchi K, et al. Metabolite changes and gender differences in schizophrenia using 3-Tesla proton magnetic resonance spectroscopy (1H-MRS). Schizophr Res 2009;108(1-3):69-77.