A cross-study meta-analysis and three-dimensional comparison of cell counting in the anterior cingulate cortex of schizophrenic and bipolar brain

Schizophrenia Research

Volumn 73, Issue 1, 2005, Pages 79-89

  Todtenkopf, Mark S ^b   Vincent, Stephen L ^b   Benes, Francine M ^a  

^a MCLEAN HOSPITAL   (United States)

^b NONE

Author keywords

Glia; Layer II; Nonpyramidal neurons; Pyramidal neurons

Indexed keywords

TYROSINE 3 MONOOXYGENASE;

ARTICLE; BIPOLAR DISORDER; BRAIN NERVE CELL; CELL COUNT; CELL DENSITY; CINGULATE GYRUS; CLINICAL TRIAL; COMPARATIVE STUDY; FOLLOW UP; GLIA CELL; HUMAN; INTERNEURON; META ANALYSIS; MOOD DISORDER; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; SCHIZOAFFECTIVE PSYCHOSIS; SCHIZOPHRENIA; STATISTICAL SIGNIFICANCE;

BIPOLAR DISORDER; CELL COUNT; COHORT STUDIES; GYRUS CINGULI; HUMANS; IMAGING, THREE-DIMENSIONAL; INTERNEURONS; NEUROGLIA; PYRAMIDAL CELLS; SCHIZOPHRENIA;

EID: 9644291599     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.schres.2004.08.018     Document Type: Article

References (41)

1. S. Akbarian, J.J. Kim, S.G. Potkin, J.O. Hagman, A. Tafazzoli, W.E. Bunney, and E.G. Jones Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics Arch. Gen. Psychiatry 52 1995 258 278
2. S.E. Arnold, B.R. Franz, R.C. Gur, R.E. Gur, R.M. Shapiro, P.J. Moberg, and J.Q. Trojanowski Smaller neuron size in schizophrenia in hippocampal subfields that mediate cortical-hippocampal interactions Am. J. Psychiatry 152 1995 738 748
3. F.M. Benes Post-mortem structural analyses of schizophrenic brain: study designs and the interpretation of data Psychiatr. Dev. 6 1988 213 226
4. F.M. Benes Is there evidence for neuronal loss in schizophrenia? Int. Rev. Psychiatry 9 1997 429 436
5. F.M. Benes Model generation and testing to probe neural circuitry in the cingulate cortex of postmortem schizophrenic brain Schizophr. Bull. 24 1998 219 230
6. F.M. Benes Emerging principles of altered neural circuitry in schizophrenia Brain Res. Brain Res. Rev. 31 2000 251 269
7. F.M. Benes Reply Biol. Psychiatry 51 2002 842 846
8. F.M. Benes, and E.D. Bird An analysis of the arrangement of neurons in the cingulate cortex of schizophrenic patients Arch. Gen. Psychiatry 44 1987 608 616
9. F.M. Benes, and N. Lange Two-dimensional versus three-dimensional cell counting: a practical perspective Trends Neurosci. 24 2001 11 17
10. F.M. Benes, J. Davidson, and E.D. Bird Quantitative cytoarchitectural studies of cerebral cortex of schizophrenics Arch. Gen. Psychiatry 43 1986 31 35
11. F.M. Benes, S.W. Matthysse, J. Davidson, and E.D. Bird The spatial distribution of neurons and glia in human cortex based on the Poisson distribution Anal. Quant. Cytol. Histol. 9 1987 531 534
12. F.M. Benes, J. McSparren, E.D. Bird, S.L. Vincent, and J.P. SanGiovanni Deficits in small interneurons in prefrontal and anterior cingulate cortex of schizophrenic and schizoaffective patients Arch. Gen. Psychiatry 48 1991 996 1001
13. F.M. Benes, I. Sorensen, and E.D. Bird Reduced neuronal size in posterior hippocampus of schizophrenic patients Schizophr. Bull. 17 1991 597 608
14. F.M. Benes, S.L. Vincent, G. Alsterberg, E.D. Bird, and J.P. SanGiovanni Increased GABAA receptor binding in superficial layers of cingulate cortex in schizophrenics J. Neurosci. 12 1992 924 929
15. F.M. Benes, M.S. Todtenkopf, and J.B. Taylor Differential distribution of tyrosine hydroxylase fibers on small and large neurons in layer II of anterior cingulate cortex of schizophrenic brain Synapse 25 1997 80 92
16. F.M. Benes, E.W. Kwok, S.L. Vincent, and M.S. Todtenkopf A reduction of nonpyramidal cells in sector CA2 of schizophrenics and manic depressives [see comments] Biol. Psychiatry 44 1998 88 97
17. F.M. Benes, M.S. Todtenkopf, P. Logiotatos, and M. Williams Glutamate decarboxylase(65)-immunoreactive terminals in cingulate and prefrontal cortices of schizophrenic and bipolar brain J. Chem. Neuroanat. 20 2000 259 269
18. F.M. Benes, S.L. Vincent, and M.S. Todtenkopf The density of pyramidal and nonpyramidal neurons in anterior cingulate cortex of schizophrenic and bipolar subjects Biol. Psychiatry 2001 (in press)
19. F.M. Benes, J. Walsh, S. Bhattacharyya, A. Sheth, and S. Berretta DNA fragmentation decreased in schizophrenia but not bipolar disorder Arch. Gen. Psychiatry 60 2003 359 364
20. P. Casaccia-Bonnefil, E. Benedikz, R. Rai, and P.J. Bergold Excitatory and inhibitory pathways modulate kainate excitotoxicity in hippocampal slice cultures Neurosci. Lett. 154 1993 5 8
21. E.J. Colon Quantitative cytoarchitectonics of the human cerebral cortex in schizophrenic dementia Acta Neuropathol. 20 1972 1 10
22. D. Cotter, D. Mackay, S. Landau, R. Kerwin, and I. Everall Reduced glial cell density and neuronal size in the anterior cingulate cortex in major depressive disorder Arch. Gen. Psychiatry 58 2001 545 553
23. D.R. Cotter, C.M. Pariante, and I.P. Everall Glial cell abnormalities in major psychiatric disorders: the evidence and implications Brain Res. Bull. 55 2001 585 595
24. J.T. Coyle, and P. Puttfarcken Oxidative stress, glutamate and neurodegenerative disorders Science 262 1993 689 695
25. P. Falkai, and B. Bogerts Cell loss in the hippocampus of schizophrenics Eur. Arch. Psychiatr. Neurol. Sci. 236 1986 154 161
26. P. Falkai, B. Bogerts, and M. Rozumek Limbic pathology in schizophrenia: the entorhinal region-a morphometric study Biol. Psychiatry 24 1988 515 521
27. J.P. Feighner, E. Robins, and S.B. Guze Diagnostic criteria for use in psychiatric research Arch. Gen. Psychiatry 26 1972 57 63
28. S. Heckers, H. Heinsen, B. Geiger, and H. Beckmann Hippocampal neuron number in schizophrenia Arch. Gen. Psychiatry 48 1991 1002 1008
29. D.V. Jeste, and J.B. Lohr Hippocampal pathologic findings in schizophrenia. A morphometric study Arch. Gen. Psychiatry 46 1989 1019 1024
30. E. Kraepelin Dementia Praecox and Paraphrenia 1919 E. and S. Livingston Edinburg
31. H.K. Manji, G.J. Moore, G. Rajkowska, and G. Chen Neuroplasticity and cellular resilience in mood disorders Mol. Psychiatry 5 2000 578 593
32. R.L. Margolis, D.M. Chuang, and R.M. Post Programmed cell death: implications for neuropsychiatric disorders Biol. Psychiatry 35 1994 946 956
33. D. Ongur, W.C. Drevets, and J.L. Price Glial reduction in the subgenual prefrontal cortex in mood disorders Proc. Natl. Acad. Sci. U. S. A. 95 1998 13290 13295
34. B. Pakkenberg Pronounced reduction of total neuron number in mediodorsal thalamic nucleus and nucleus accumbens in schizophrenic brain Arch. Gen. Psychiatry 47 1990 1023 1028
35. H. Pollard, C. Charriaut Marlangue, S. Cantagrel, A. Represa, O. Robain, J. Moreau, and Y. Ben Ari Kainate-induced apoptotic cell death in hippocampal neurons Neuroscience 63 1994 7 18
36. G. Rajkowska, A. Halaris, and L.D. Selemon Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder Biol. Psychiatry 49 2001 741 752
37. R. Schwarcz, and J.T. Coyle Striatal lesion with kainic acid: neurochemical characteristics Brain Res. 127 1977 235 249
38. Selemon, L.D., Rajkowska, G., 2002. Two-dimensional versus three-dimensional cell counting. Biol. Psychiatry 51, 838-840; author reply, 842-836.
39. Selemon, L.D., Rajkowska, G., Goldman-Rakic, P.S., 1995. Abnormally high neuronal density in the schizophrenic cortex. A morphometric analysis of prefrontal area 9 and occipital area 17. Arch. Gen. Psychiatry 52, 805-818; discussion 819-820.
40. H.B.M. Uylings About assumptions in estimation of density of neurons and glial cells Biol. Psychiatry 51 2002 840 842
41. T.W. Woo, J.P. Walsh, and F.M. Benes Density of glutamic acid decarboxylase 67 mRNA containing neurons that express the N-methyl-d-aspartate subunit NR2A is decreased in the anterior cingulate cortex in schizophrenic and bipolar brain Arch. Gen. Psychiatry 2004 (in press)