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1H magnetic resonance spectroscopy in patients with schizophrenia: a systematic review and meta-analysis. Neuropsychology 2005; 30:1949-1962. This study is the first meta-analysis completed in the literature for proton spectroscopy and schizophrenia; this meta-analysis examines the results of NAA in various brain regions and compares NAA in first-episode and chronic patients. There is compelling evidence for NAA reduction in schizophrenia. Publication bias cannot be completely excluded.
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