Up-regulation of NDRG2 in senescent lens epithelial cells contributes to age-related cataract in human

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Zhang, Zi Feng ^a   Zhang, Jian ^b   Hui, Yan Nian ^a   Zheng, Min Hua ^b   Liu, Xin Ping ^b   Kador, Peter F ^c,d   Wang, Yu Sheng ^a   Yao, Li Bo ^b   Zhou, Jian ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^d UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; HYDROGEN PEROXIDE; MESSENGER RNA; MYC PROTEIN; N MYC DOWNSTREAM REGULATED GENE 2 PROTEIN; UNCLASSIFIED DRUG; NDRG2 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

ADULT; AGE RELATED CATARACT; AGED; ANIMAL TISSUE; ARTICLE; CATARACT; CATARACTOGENESIS; CELL AGING; CELL LEVEL; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; FIBROBLAST; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LENS EPITHELIUM; LONG TERM EXPOSURE; MALE; N MYC DOWNSTREAM REGULATED GENE 2; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; UPREGULATION; CELL CULTURE; CELL SHAPE; CELL SURVIVAL; CYTOLOGY; DRUG EFFECT; EPITHELIUM CELL; LENS; METABOLISM; PHYSIOLOGY;

CATARACT; CELL AGING; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; CELLS, CULTURED; EPITHELIAL CELLS; HUMANS; HYDROGEN PEROXIDE; LENS, CRYSTALLINE; OXIDATIVE STRESS; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 80054768656     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026102     Document Type: Article

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