Breastmilk ghrelin, leptin, and fat levels changing foremilk to hindmilk: Is that important for self-control of feeding?

European Journal of Pediatrics

Volumn 170, Issue 10, 2011, Pages 1273-1280

  Karatas, Zehra ^a   Durmus Aydogdu, Sultan ^b   Dinleyici, Ener Cagri ^b   Colak, Omer ^b   Dogruel, Nesrin ^b  

^a SELCUK UNIVERSITY   (Turkey)

^b ESKISEHIR OSMANGAZI UNIVERSITY   (Turkey)

Author keywords

Breast milk; Fat; Ghrelin; Growth; Leptin; Self regulation of feeding

Indexed keywords

CHOLESTEROL; GHRELIN; LEPTIN; TRIACYLGLYCEROL;

ARTICLE; ARTIFICIAL MILK; BODY MASS; BREAST FEEDING; BREAST MILK; COLOSTRUM; CONTROLLED STUDY; FATTY ACID BLOOD LEVEL; HUMAN; INFANT; MAJOR CLINICAL STUDY; NEWBORN; NUTRITION; PRIORITY JOURNAL; SELF CONTROL; WEIGHT GAIN;

BODY WEIGHT; BREAST FEEDING; CHILD DEVELOPMENT; COLOSTRUM; FATTY ACIDS; FEMALE; GHRELIN; HUMANS; INFANT; INFANT FOOD; LEPTIN; MILK, HUMAN; PREGNANCY;

EID: 80054764459     PISSN: 03406199     EISSN: 14321076     Source Type: Journal    
DOI: 10.1007/s00431-011-1438-1     Document Type: Article

References (45)

1. C Agostini F Grandi ML Gianni, et al. 1999 Growth patterns of breast fed and formula fed infants in the first 12 months of life: an Italian study Arch Dis Child 81 395 399 10.1136/adc.81.5.395 (Pubitemid 29501369)
2. S Aydin S Aydin Y Ozkan, et al. 2006 Ghrelin is present in human colostrum, transitional and mature milk Peptides 27 878 882 16191452 10.1016/j.peptides.2005.08.006 1:CAS:528:DC%2BD28XjtFWqs7c%3D
3. CJ Bartok AK Ventura 2009 Mechanisms underlying the association between breastfeeding and obesity Int J Pediatr Obes 4 196 204 19922033 10.3109/17477160902763309
4. NJ Beaumont VO Skinner TM Tan, et al. 2003 Ghrelin can bind to a species of high density lipoprotein associated with paraoxonase J Biol Chem 278 8877 8880 12531885 10.1074/jbc.C200575200 1:CAS:528:DC%2BD3sXhvVyqsbc%3D (Pubitemid 36800362)
5. B Beck N Musse A Stricker-Krongrad 2002 Ghrelin macronutrient intake and dietary preferences in long-evans rats Biochem Biophys Res Commun 292 1031 1035 11944918 10.1006/bbrc.2002.6737 1:CAS:528:DC%2BD38Xis1ygtLw%3D (Pubitemid 34687308)
6. I Bedendi G Alloatti A Marcantoni, et al. 2003 Cardiac effects of ghrlin and its endognous derivates des-octanoyl ghrelin and des-Gln14-ghrelin Eur J Pharmacol 476 87 95 12969753 10.1016/S0014-2999(03)02083-1 1:CAS:528: DC%2BD3sXntVCnur0%3D (Pubitemid 37315540)
7. WA Blom A Stafleu C de Graaf, et al. 2005 Ghrelin response to carbohydrate-enriched breakfast is related to insulin Am J Clin Nutr 81 367 375 15699223 1:CAS:528:DC%2BD2MXhsFens7c%3D (Pubitemid 43073337)
8. S Bluher CS Mantzoros 2004 The role of leptin in regulating neuroendocrine function in humans J Nutr 134 2469 2474
9. M Bonnet C Delavaud K Laud, et al. 2002 Mammary leptin synthesis, milk leptin and their putative physiological roles Reprod Nutr Dev 42 399 413 12537253 10.1051/rnd:2002034 1:CAS:528:DC%2BD3sXps1Oltw%3D%3D (Pubitemid 36113383)
10. F Broglio C Gottero F Prodam, et al. 2004 Non-acylated ghrelin counteracts the metabolic but not the endocrine response to acylated ghrelin in humans J Clin Endocrinol Metab 89 3062 3065 15181099 10.1210/jc.2003-031964 1:CAS:528:DC%2BD2cXmtlKjsb0%3D (Pubitemid 38766409)
11. PG Cammisotto M Bendayan 2007 Leptin secretion by white adipose tissue and gastric mucusa Histol Histopathol 22 199 210 17149693 1:CAS:528: DC%2BD2sXjt1Khu7g%3D (Pubitemid 46117106)
12. X Casabiell V Pineiro MA Tome 1997 Presence of leptin in colostrum and/or breast milk from lactating mothers: apotential role in the regülation of neonatal food intake J Clin Endocrinol Metab 82 4270 4273 9398752 10.1210/jc.82.12.4270 1:CAS:528:DyaK2sXnvFyrtLk%3D (Pubitemid 27525552)
13. EC Claud T Savidge WA Walker 2003 Modulation of human intestinal epithelial cell IL-8 secretion by human milk factors Pediatr Res 53 419 425 12595589 10.1203/01.PDR.0000050141.73528.AD 1:CAS:528:DC%2BD3sXht1Cmur8%3D (Pubitemid 36237396)
14. RV Considine MK Sinha ML Heiman, et al. 1996 Serum immunoreactive-leptin concentrations in normal-weight and obese humans N Engl J Med 334 292 295 8532024 10.1056/NEJM199602013340503 1:STN:280:DyaK287jtlOnsw%3D%3D (Pubitemid 26033933)
15. AP Davenport TI Bonner SM Foord, et al. 2005 International Union of Pharmacology. LVI. Ghrelin receptor nomenclature, distribution and function Pharmacol Rev 57 541 546 16382107 10.1124/pr.57.4.1 1:CAS:528: DC%2BD28XhtFWnsrg%3D (Pubitemid 43036440)
16. KG Dewey MJ Heinig LA Nommsen, et al. 1992 Growth of breast-fed and formula-fed infants from 0 to 18 months: the DARLING study Pediatrics 89 1035 1041 1594343 1:STN:280:DyaK383nvVyqsw%3D%3D
17. F Dykes C Williams 1999 Falling by the wayside: a phenomenological exploration of perceived breast-milk inadequacy in lactating women Midwifery 15 232 246 11216257 10.1054/midw.1999.0185 1:STN:280:DC%2BD3M7ns12lug%3D%3D
18. WB Emery 3rd NL Canolty JM Aitchison, et al. 1978 Influence of sampling on fatty acid composition of human milk Am J Clin Nutr 31 1127 1130 665562 1:CAS:528:DyaE1cXlsVGhsLc%3D (Pubitemid 8395581)
19. T Fry 2003 The new "breast from birth" growth charts. An updated version of the paper given at the Primary Care Conference and Exhibition J Fam Health Care 13 124 126 14666846
20. M Hamosh 2001 Bioactive factors in human milk Pediatr Clin N Am 48 69 86 10.1016/S0031-3955(05)70286-8 1:STN:280:DC%2BD3M7otlGqtw%3D%3D (Pubitemid 32193128)
21. H Hosoda K Doi N Nagaya, et al. 2004 Optimum collection and storage conditions for ghrelin measurements: octanoyl modification of ghrelin is rapidly hydrolyzed to desacyl ghrelin in blood samples Clin Chem 50 1077 1080 15161728 10.1373/clinchem.2003.025841 1:CAS:528:DC%2BD2cXltFOjsLY%3D (Pubitemid 38725803)
22. H Hosoda M Kojima K Kangawa 2006 Biological, physiological, and pharmacological aspects of ghrelin J Pharmacol Sci 100 398 410 16612045 10.1254/jphs.CRJ06002X 1:CAS:528:DC%2BD28XmvVWqu7Y%3D (Pubitemid 44609531)
23. KL Houseknecht MK McGuire CP Portocarrero, et al. 1997 Leptin in present in human milk and is related to maternal plasma leptin concentrations and adiposity Biochem Biophys Res Commun 240 742 747 9398637 10.1006/bbrc.1997.7736 1:CAS:528:DyaK2sXnslGms7k%3D (Pubitemid 28271789)
24. MJ Heinig LA Nommsen JM Peerson, et al. 1993 Intake and growth of breast-fed and formula-fed infants in relation to the timing of introduction of complementary foods: the DARLING study Acta Paediatr 82 999 1006 8155936 10.1111/j.1651-2227.1993.tb12798.x 1:STN:280:DyaK2c3gslantA%3D%3D (Pubitemid 24051386)
25. YO Ilcol B Hizli 2007 Active and total ghrelin concentrations increase in breast milk during lactation Acta Paediatr 96 1632 1639 17888057 10.1111/j.1651-2227.2007.00493.x (Pubitemid 47609782)
26. IC Jeusette ET Lhoest LP Istasse, et al. 2005 Influence of obesity on plasma lipid and lipoprotein concentrations in dogs Am J Vet Res 66 81 86 15691040 10.2460/ajvr.2005.66.81 1:CAS:528:DC%2BD2MXotF2hsQ%3D%3D (Pubitemid 40214488)
27. JA Kierson DM Dimatteo RG Locke, et al. 2006 Ghrelin and cholecystokinin in term and preterm human breast milk Acta Paediatr 95 991 995 16882575 10.1080/08035250600669769 (Pubitemid 44181222)
28. M Kojima K Kangawa 2005 Ghrelin: structure and function Physiol Rev 85 495 522 15788704 10.1152/physrev.00012.2004 1:CAS:528:DC%2BD2MXjt12lsL4%3D (Pubitemid 40404635)
29. M Lage R Baldelli JP Camiña, et al. 2002 Presence of bovine leptin in edible commercial milk and infant formula J Endocrinol Investig 25 670 674 1:CAS:528:DC%2BD38XnslCqsr8%3D
30. R Li SB Fein LM Grummer-Strawn 2010 Do infants fed from bottles lack self-regulation of milk intake compared with directly breastfed infants? Pediatrics 125 1386 1393 10.1542/peds.2009-2549
31. RE Lyle SC Kincaid JC Bryant, et al. 2001 Human milk contains detectable levels of immunoreactive leptin Adv Exp Med Biol 501 87 92 11787735 1:CAS:528:DC%2BD38XivFejurg%3D (Pubitemid 34102182)
32. LR Mitoulas JC Kent DB Cox PE Hartmann, et al. 2002 Variation in fat, lactose and protein in human milk over 24 h and throughout the first year of lactation Br J Nutr 88 29 37 12117425 10.1079/BJN2002579 1:CAS:528: DC%2BD38XmsF2ms74%3D (Pubitemid 34752312)
33. V Mohammed-Ali SJ Goodrick SA Stanner, et al. 1996 Adipose tissue leptin production at fasting and after a high carbohydrate meal (Abstract) Diabet Med 13 19
34. AM Nelson 2006 A metasynthesis of qualitative breastfeeding studies J Midwifery Womens Health 51 13 20
35. LA Nommsen-Rivers KG Dewey 2009 Growth of breastfed infants Breastfeed Med 4 45 49 10.1089/bfm.2009.0048
36. D O'Connor V Funanage R Locke, et al. 2003 Leptin is not present in infant formulas J Endocrinol Investig 26 490 (Pubitemid 36896334)
37. MA Pelleymounter MJ Cullen MB Baker, et al. 1995 Effects of the obese gene product on body weight regülation in ob/ob mice Science 269 500 543 10.1126/science.7624776
38. T Petruchke K Rotrig H Hauner 1994 Transforming growth factor beta inhibits the differentiation of human adipocyte precursor cells in primary culture Int J Obes Metab Disord 18 532 536 (Pubitemid 24237579)
39. M Resto D O'Connor K Leef, et al. 2001 Leptin levels in preterm human breast milk and infant formula Pediatrics 108 15 18 10.1542/peds.108.1.e15
40. T Saarela J Kokkonen M Koivisto 2005 Macronutrient and energy contents of human milk fractions during the first six months of lactation Acta Paediatr 94 1176 1181 16203669 10.1080/08035250510036499 (Pubitemid 41510607)
41. F Savino MF Fissore SA Liguori, et al. 2009 Can hormones contained in mothers' milk account for the beneficial effect of breast-feeding on obesity in children? Clin Endocrinol Oxf 71 757 765 19302580 10.1111/j.1365-2265.2009. 03585.x 1:CAS:528:DC%2BD1MXhs1SjtbzI
42. RJ Stocks DP Davies F Allen, et al. 1985 Loss of breast milk nutrients during tube feeding Arch Dis Child 60 164 166 3919654 10.1136/adc.60.2.164 1:STN:280:DyaL2M7kslyqtw%3D%3D (Pubitemid 15085056)
43. B Ucar B Kirel O Bor, et al. 2000 Breast milk leptin concentrations in initial and terminal milk samples: relationships to maternal and infant plasma leptin concentrations, adiposity, serum glucose, insulin, lipid and lipoprotein levels J Pediatr Endocrinol Metab 13 149 156 10711659 10.1515/JPEM.2000.13.2.149 1:STN:280:DC%2BD3c7nsVyjsw%3D%3D (Pubitemid 30117209)
44. J Woliński R Zabielski 2005 Presence of leptin in mammalian colostrum and milk and in artificial milk formulas Med Wieku Rozwoj 9 629 636 16733273
45. AJ Van der Lely M Tschöp ML Heiman, et al. 2004 Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin Endocr Rev 25 426 457 15180951 10.1210/er.2002-0029 (Pubitemid 38780667)