Interaction between the D2 dopamine receptor and neuronal calcium sensor-1 analyzed by fluorescence anisotropy

Biochemistry

Volumn 50, Issue 41, 2011, Pages 8780-8791

  Woll, Matthew P ^a   De Cotiis, Dan A ^a   Bewley, Maria C ^a   Tacelosky, Diana M ^a   Levenson, Robert ^a   Flanagan, John M ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BEST FIT; CALCIUM BINDING; CALCIUM BINDING PROTEINS; CELL LYSATES; CO-IMMUNOPRECIPITATION EXPERIMENTS; COFACTORS; EF-HAND; FLUORESCENCE ANISOTROPY; HEK-293; MAGNESIUM IONS; MONOMERIC FORMS; NEURONAL CALCIUM SENSOR-1; SMALL-MOLECULE DRUGS; STRUCTURAL MODELS; TITRATION CURVES;

ANISOTROPY; BRAIN; DRUG INTERACTIONS; EXPERIMENTS; FLUORESCENCE; MAGNESIUM; METAL IONS; MODEL STRUCTURES; MONOMERS; OLIGOMERIZATION; OLIGOMERS; PEPTIDES; SENSORS; TITRATION;

CALCIUM;

CALCIUM; DOPAMINE 2 RECEPTOR; MAGNESIUM ION; NEURONAL CALCIUM SENSOR; NEURONAL CALCIUM SENSOR 1; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CALCIUM BINDING; CELL STRAIN HEK293; CHEMICAL INTERACTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIMERIZATION; FLUORESCENCE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE;

ANISOTROPY; BINDING SITES; CALCIUM; HEK293 CELLS; HUMANS; KINETICS; LIGHT; MAGNESIUM; NEURONAL CALCIUM-SENSOR PROTEINS; NEUROPEPTIDES; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, DOPAMINE D2; SCATTERING, RADIATION; SPECTROMETRY, FLUORESCENCE;

EID: 80054757503     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi200637e     Document Type: Article

References (45)

1. 2+-sensor proteins: Multitalented regulators of neuronal function Trends Neurosci. 27, 203-209 (Pubitemid 38376407)
2. Nef, S., Fiumelli, H., de Castro, E., Raes, M. B., and Nef, P. (1995) Identification of neuronal calcium sensor (NCS-1) possibly involved in the regulation of receptor phosphorylation J. Recept. Signal Transduction Res. 15, 365-378
3. 2+ sensor 1, the mammalian homologue of frequenin, is expressed in chromaffin and PC12 cells and regulates neurosecretion from dense-core granules J. Biol. Chem. 273, 22768-22772 (Pubitemid 28399850)
4. Kabbani, N., Negyessy, L., Lin, R., Goldman-Rakic, P., and Levenson, R. (2002) Interaction with neuronal calcium sensor NCS-1 mediates desensitization of the D2 dopamine receptor J. Neurosci. 22, 8476-8486 (Pubitemid 35387588)
5. Handley, M. T., Lian, L. Y., Haynes, L. P., and Burgoyne, R. D. (2011) Structural and functional deficits in a neuronal calcium sensor-1 mutant identified in a case of autistic spectrum disorder PLoS One 5, e10534
6. Koh, P. O., Undie, A. S., Kabbani, N., Levenson, R., Goldman-Rakic, P. S., and Lidow, M. S. (2003) Up-regulation of neuronal calcium sensor-1 (NCS-1) in the prefrontal cortex of schizophrenic and bipolar patients Proc. Natl. Acad. Sci. U.S.A. 100, 313-317 (Pubitemid 36078071)
7. Lidow, M. S. (2003) Calcium signaling dysfunction in schizophrenia: A unifying approach Brain Res. Brain Res. Rev. 43, 70-84 (Pubitemid 37130081)
8. 2+ sensor-1 as a survival factor up-regulated in injured neurons J. Cell Biol. 172, 1081-1091
9. Aronica, E., Boer, K., Doorn, K. J., Zurolo, E., Spliet, W. G., van Rijen, P. C., Baayen, J. C., Gorter, J. A., and Jeromin, A. (2009) Expression and localization of voltage dependent potassium channel Kv4.2 in epilepsy associated focal lesions Neurobiol. Dis. 36, 81-95
10. Kawasaki, H. and Kretsinger, R. H. (1994) Calcium-binding proteins. 1: EF-hands Protein Profile 1, 343-517
11. 2+-binding proteins Biochem. J. 353, 1-12 (Pubitemid 32094594)
12. Rajebhosale, M., Greenwood, S., Vidugiriene, J., Jeromin, A., and Hilfiker, S. (2003) Phosphatidylinositol 4-OH kinase is a downstream target of neuronal calcium sensor-1 in enhancing exocytosis in neuroendocrine cells J. Biol. Chem. 278, 6075-6084 (Pubitemid 36800859)
13. 2+ channels in bovine adrenal chromaffin cells J. Biol. Chem. 275, 40082-40087 (Pubitemid 32064633)
14. Haynes, L. P., Fitzgerald, D. J., Wareing, B., O'Callaghan, D. W., Morgan, A., and Burgoyne, R. D. (2006) Analysis of the interacting partners of the neuronal calcium-binding proteins L-CaBP1, hippocalcin, NCS-1 and neurocalcin delta Proteomics 6, 1822-1832
15. Cox, J. A., Durussel, I., Comte, M., Nef, S., Nef, P., Lenz, S. E., and Gundelfinger, E. D. (1994) Cation binding and conformational changes in VILIP and NCS-1, two neuron-specific calcium-binding proteins J. Biol. Chem. 269, 32807-32813
16. 2+ differentially regulate DNA binding and dimerization of DREAM J. Biol. Chem. 280, 18008-18014 (Pubitemid 41389044)
17. 2+ cation binding cycle of guanylyl cyclase activating proteins (GCAPs): Role in regulation of photoreceptor guanylyl cyclase Mol. Cell. Biochem. 334, 117-124
18. Permyakov, S. E., Nazipova, A. A., Denesyuk, A. I., Bakunts, A. G., Zinchenko, D. V., Lipkin, V. M., Uversky, V. N., and Permyakov, E. A. (2007) Recoverin as a redox-sensitive protein J. Proteome Res. 6, 1855-1863 (Pubitemid 46814509)
19. De Cotiis, D. A., Woll, M. P., Fox, T. E., Hill, R. B., Levenson, R., and Flanagan, J. M. (2008) Optimized expression and purification of myristoylated human neuronal calcium sensor 1 in E. coli Protein Expression Purif. 61, 103-112
20. Studier, F. W. (2005) Protein production by auto-induction in high density shaking cultures Protein Expression Purif. 41, 207-234
21. Riddles, P. W., Blakeley, R. L., and Zerner, B. (1983) Reassessment of Ellman's reagent Methods Enzymol. 91, 49-60
22. Bevington, P. R. and Robinson, D. K. (1992) Data Reduction and Error Analysis for The Physical Sciences, McGraw-Hill, New York.
23. Lebowitz, J., Lewis, M. S., and Schuck, P. (2002) Modern analytical ultracentrifugation in protein science: A tutorial review Protein Sci. 11, 2067-2079 (Pubitemid 34919611)
24. Minton, A. P. (1990) Quantitative characterization of reversible molecular associations via analytical centrifugation Anal. Biochem. 190, 1-6 (Pubitemid 20350122)
25. Harpaz, Y., Gerstein, M., and Chothia, C. (1994) Volume changes on protein folding Structure 2, 641-649
26. de Vries, S. J., van Dijk, M., and Bonvin, A. M. (2010) The HADDOCK web server for data-driven biomolecular docking Nat. Protoc. 5, 883-897
27. Roehrl, M. H., Wang, J. Y., and Wagner, G. (2004) Discovery of small-molecule inhibitors of the NFAT-calcineurin interaction by competitive high-throughput fluorescence polarization screening Biochemistry 43, 16067-16075 (Pubitemid 40041020)
28. Feigin, L. A. and Svergun, D. I. (1987) Structure Analysis by Small Angle X-ray and Neutron Scattering, Plenum Press, New York.
29. Ben-Jonathan, N. and Hnasko, R. (2001) Dopamine as a prolactin (PRL) inhibitor Endocr. Rev. 22, 724-763 (Pubitemid 34214293)
30. Langley, K. and Grant, N. J. (1997) Are exocytosis mechanisms neurotransmitter specific? Neurochem. Int. 31, 739-757 (Pubitemid 27493962)
31. 2+ binding, myristoylation, and dimerization of the neuronal calcium sensor and visinin-like protein 1 (VILIP-1) J. Biol. Chem. 286, 6354-6366
32. 2+-induced conformational changes, and equilibrium unfolding transitions J. Mol. Biol. 376, 1100-1115
33. Muralidhar, D., Jobby, M. K., Krishnan, K., Annapurna, V., Chary, K. V., Jeromin, A., and Sharma, Y. (2005) Equilibrium unfolding of neuronal calcium sensor-1: N-terminal myristoylation influences unfolding and reduces protein stiffening in the presence of calcium J. Biol. Chem. 280, 15569-15578 (Pubitemid 40616673)
34. Bourne, Y., Dannenberg, J., Pollmann, V., Marchot, P., and Pongs, O. (2001) Immunocytochemical localization and crystal structure of human frequenin (neuronal calcium sensor 1) J. Biol. Chem. 276, 11949-11955
35. 2+-binding helix-loop-helix EF-hand motifs Biochem. J. 405, 199-221 (Pubitemid 47075156)
36. Chandra, K., Ramakrishnan, V., Sharma, Y., and Chary, K. V. (2011) N-terminal myristoylation alters the calcium binding pathways in neuronal calcium sensor-1 J. Biol. Inorg. Chem. 16, 81-95
37. Chien, E. Y., Liu, W., Zhao, Q., Katritch, V., Han, G. W., Hanson, M. A., Shi, L., Newman, A. H., Javitch, J. A., Cherezov, V., and Stevens, R. C. (2010) Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist Science 330, 1091-1095
38. Vijay-Kumar, S. and Kumar, V. D. (1999) Crystal structure of recombinant bovine neurocalcin Nat. Struct. Biol. 6, 80-88 (Pubitemid 29232428)
39. Stephen, R., Bereta, G., Golczak, M., Palczewski, K., and Sousa, M. C. (2007) Stabilizing function for myristoyl group revealed by the crystal structure of a neuronal calcium sensor, guanylate cyclase-activating protein 1 Structure 15, 1392-1402 (Pubitemid 350051925)
40. Chandra, K., Sharma, Y., and Chary, K. V. (2011) Characterization of low-energy excited states in the native state ensemble of non-myristoylated and myristoylated neuronal calcium sensor-1 Biochim. Biophys. Acta 1814, 334-344
41. 2+-myristoyl switch protein that controls activation of a phosphatidylinositol 4-kinase in fission yeast J. Biol. Chem. 286, 12565-12577
42. Strahl, T., Huttner, I. G., Lusin, J. D., Osawa, M., King, D., Thorner, J., and Ames, J. B. (2007) Structural insights into activation of phosphatidylinositol 4-kinase (Pik1) by yeast frequenin (Frq1) J. Biol. Chem. 282, 30949-30959 (Pubitemid 350035236)
43. Armstrong, D. and Strange, P. G. (2001) Dopamine D2 receptor dimer formation: Evidence from ligand binding J. Biol. Chem. 276, 22621-22629
44. Kabbani, N. and Levenson, R. (2007) A proteomic approach to receptor signaling: Molecular mechanisms and therapeutic implications derived from discovery of the dopamine D2 receptor signalplex Eur. J. Pharmacol. 572, 83-93 (Pubitemid 47429650)
45. Pettersen, E. F., Goddard, T. D., Huang, C. C., Couch, G. S., Greenblatt, D. M., Meng, E. C., and Ferrin, T. E. (2004) UCSF Chimera: A visualization system for exploratory research and analysis J. Comput. Chem. 25, 1605-1612