Regulatory and Structural EF-Hand Motifs of Neuronal Calcium Sensor-1: Mg2+ Modulates Ca2+ Binding, Ca2+-Induced Conformational Changes, and Equilibrium Unfolding Transitions

Journal of Molecular Biology

Volumn 376, Issue 4, 2008, Pages 1100-1115

  Aravind, Penmatsa ^a   Chandra, Kousik ^b   Reddy, Pasham Parameshwar ^a   Jeromin, Andreas ^c   Chary, K V R ^b   Sharma, Yogendra ^a  

^a CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

^b TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

^c ALLEN INSTITUTE FOR BRAIN SCIENCE   (United States)

Author keywords

Ca2+ Mg2+ exchange; EF hand motifs; equilibrium unfolding; NCS 1; structural and regulatory sites

Indexed keywords

CALCIUM ION; MAGNESIUM ION; NEURONAL CALCIUM SENSOR; NEURONAL CALCIUM SENSOR 1; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CALCIUM BINDING; CALCIUM HOMEOSTASIS; CONFORMATIONAL TRANSITION; FLUORESCENCE; HYDROPHOBICITY; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN STRUCTURE; QUANTUM CHEMISTRY; TITRIMETRY;

EID: 39049105983     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.12.033     Document Type: Article

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