Optimization of the Caco-2 Permeability Assay to Screen Drug Compounds for Intestinal Absorption and Efflux

Methods in Molecular Biology

Volumn 763, Issue , 2011, Pages 139-154

  Press, Barry ^a  

^a ONTARIO INSTITUTE FOR CANCER RESEARCH   (Canada)

Author keywords

Absorption; Bioavailability; Caco 2; Efflux; Enterocyte; Epithelial monolayer; P gp; Permeability

Indexed keywords

ABC TRANSPORTER; ABCG2 PROTEIN, HUMAN; CARRIER PROTEIN; DIGOXIN; TUMOR PROTEIN; VINBLASTINE;

ABSORPTION; ARTICLE; BIOASSAY; BIOAVAILABILITY; BIOLOGICAL MODEL; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; CULTURE TECHNIQUE; CYTOLOGY; DIFFUSION CHAMBER; DRUG ANTAGONISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTESTINE; INTESTINE ABSORPTION; KINETICS; MASS SPECTROMETRY; METABOLISM; PERMEABILITY; PHYSIOLOGY; QUALITY CONTROL;

ABSORPTION; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL ASSAY; BIOLOGICAL AVAILABILITY; CACO-2 CELLS; CELL CULTURE TECHNIQUES; CELL MEMBRANE PERMEABILITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIFFUSION CHAMBERS, CULTURE; DIGOXIN; HUMANS; INTESTINAL ABSORPTION; INTESTINES; KINETICS; MASS SPECTROMETRY; MEMBRANE TRANSPORT PROTEINS; MODELS, BIOLOGICAL; NEOPLASM PROTEINS; PERMEABILITY; QUALITY CONTROL; VINBLASTINE;

EID: 80054757005     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-61779-191-8_9     Document Type: Chapter

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