Binding and inhibition of human spermidine synthase by decarboxylated S-adenosylhomocysteine

Protein Science

Volumn 20, Issue 11, 2011, Pages 1836-1844

  Šečkute, Jolita ^a   McCloskey, Diane E ^b   Thomas, H Jeanette ^c   Secrist III, John A ^c   Pegg, Anthony E ^b   Ealick, Steven E ^a  

^a Cornell University ^*  (United States)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^c SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

Aminopropyltransferase; Polyamine; S adenosylhomocysteine; S adenosylmethionine; Spermidine; Spermidine synthase

Indexed keywords

PUTRESCINE; S ADENOSYLHOMOCYSTEINE; SPERMIDINE SYNTHASE; SPERMINE SYNTHASE;

ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DECARBOXYLATION; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ISOTHERMAL TITRATION CALORIMETRY; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN STRUCTURE; THERMATOGA MARITIMA; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DECARBOXYLATION; ENZYME INHIBITORS; HUMANS; PLASMODIUM FALCIPARUM; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PUTRESCINE; S-ADENOSYLHOMOCYSTEINE; SPERMIDINE; SPERMIDINE SYNTHASE; THERMOTOGA MARITIMA;

EUKARYOTA; PLASMODIUM FALCIPARUM; PROKARYOTA; THERMOTOGA MARITIMA;

EID: 80054753541     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.717     Document Type: Article

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