Preferential replication of vaccinia virus in the ovaries is independent of immune regulation through IL-10 and TGF-β

Viral Immunology

Volumn 24, Issue 5, 2011, Pages 387-396

  Zhao, Yuan ^a   Adams, Yan Fei ^a   Croft, Michael ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD134 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN G; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; MESSENGER RNA; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CELLULAR IMMUNITY; CYTOKINE PRODUCTION; DENDRITIC CELL; FEMALE; GRANULOCYTE; HEMATOPOIETIC CELL; IMMUNOCOMPETENT CELL; IMMUNOREGULATION; MACROPHAGE; MOUSE; NATURAL KILLER CELL; NONHUMAN; OVARY; PROTEIN EXPRESSION; VACCINIA VIRUS; VIRAL CLEARANCE; VIRUS INFECTION; VIRUS REPLICATION;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; HUMANS; IMMUNE EVASION; INTERLEUKIN-10; MICE; MICE, INBRED C57BL; OVARY; TRANSFORMING GROWTH FACTOR BETA; VACCINIA; VACCINIA VIRUS; VIRUS REPLICATION;

MUS; VACCINIA VIRUS;

EID: 80054738333     PISSN: 08828245     EISSN: 15578976     Source Type: Journal    
DOI: 10.1089/vim.2011.0020     Document Type: Article

References (50)

1. Smith GL, and McFadden G: Smallpox: anything to declare? Nat Rev Immunol 2002;2:521-527. (Pubitemid 37328743)
2. Gomez CE, Najera JL, Krupa M, and Esteban M: The pox-virus vectors MVA and NYVAC as gene delivery systems for vaccination against infectious diseases and cancer. Curr Gene Ther 2008;8:97-120.
3. Artenstein AW: New generation smallpox vaccines: a review of preclinical and clinical data. Rev Med Virol 2008;18:217-231. (Pubitemid 352018846)
4. Perkus ME, Taylor J, Tartaglia J, et al.: Live attenuated vaccinia and other poxviruses as delivery systems: public health issues. Ann NY Acad Sci 1995;754:222-233.
5. Shen Y, and Nemunaitis J: Fighting cancer with vaccinia virus: teaching new tricks to an old dog. Mol Ther 2005;11: 180-195. (Pubitemid 40163961)
6. Guo ZS, and Bartlett DL: Vaccinia as a vector for gene delivery. Expert Opin Biol Ther 2004;4:901-917. (Pubitemid 38843227)
7. Benning N, and Hassett DE: Vaccinia virus infection during murine pregnancy: a new pathogenesis model for vaccinia fetalis. J Virol 2004;78:3133-3139. (Pubitemid 38314371)
8. Karupiah G, Coupar B, Ramshaw I, et al.: Vaccinia virus-mediated damage of murine ovaries and protection by virus-expressed interleukin-2. Immunol Cell Biol 1990;68 (Pt 5):325-333.
9. Karupiah G, and Blanden RV: Anti-asialo-GM1 inhibits vaccinia virus infection of murine ovaries: asialo-GM1 as an additional virus receptor? Immunol Cell Biol 1990;68 (Pt 5):343-346.
10. McCart JA, Ward JM, Lee J, et al.: Systemic cancer therapy with a tumor-selective vaccinia virus mutant lacking thy-midine kinase and vaccinia growth factor genes. Cancer Res 2001;61:8751-8757. (Pubitemid 34013887)
11. Puhlmann M, Brown CK, Gnant M, et al.: Vaccinia as a vector for tumor-directed gene therapy: biodistribution of a thymidine kinase-deleted mutant. Cancer Gene Ther 2000; 7:66-73. (Pubitemid 30080989)
12. McCart JA, Mehta N, Scollard D, et al.: Oncolytic vaccinia virus expressing the human somatostatin receptor SSTR2: molecular imaging after systemic delivery using 111In-pentetreotide. Mol Ther 2004;10:553-561. (Pubitemid 39186116)
13. Humphreys IR, de Trez C, Kinkade A, et al.: Cytomegalo-virus exploits IL-10-mediated immune regulation in the salivary glands. J Exp Med 2007;204:1217-1225. (Pubitemid 46798163)
14. Barua A, and Yoshimura Y: Ovarian cell-mediated immune response to Salmonella enteritidis infection in laying hens (Gallus domesticus). Poult Sci 2004;83:997-1002. (Pubitemid 39197189)
15. Zhou C, Wu j, Borillo J, et al.: Potential roles of a special CD8 alpha alpha+ cell population and CC chemokine thymus-expressed chemokine in ovulation related inflammation. J Immunol 2009;182:596-603.
16. Su HC, Ishikawa R, and Biron CA: Transforming growth factor-beta expression and natural killer cell responses during virus infection of normal, nude, and SCID mice. J Immunol 1993;151:4874-4890.
17. Michelson S, Alcami J, Kim SJ, et al.: Human cytomegalo-virus infection induces transcription and secretion of transforming growth factor beta 1. J Virol 1994;68:5730-5737. (Pubitemid 24258588)
18. Gibbs JD, Ornoff DM, Igo HA, et al.: Cell cycle arrest by transforming growth factor beta1 enhances replication of respiratory syncytial virus in lung epithelial cells. J Virol 2009;83:12424-12431.
19. Coomes SM, Wilke CA, Moore TA, and Moore BB: Induction of TGF-beta 1, not regulatory T cells, impairs antiviral immunity in the lung following bone marrow transplant. J Immunol 2010;184:5130-5140.
20. Legrand FA, Verardi PH, Jones LA, et al.: Induction of potent humoral and cell-mediated immune responses by attenuated vaccinia virus vectors with deleted serpin genes. J Virol 2004;78:2770-2779. (Pubitemid 38314336)
21. Kohonen-Corish MR, King NJ, Woodhams CA, and Ram-shaw IA: Immunodeficient mice recover from infection with vaccinia virus expressing interferon-gamma. Eur J Immunol 1990;20:157-161. (Pubitemid 20087042)
22. Giavedoni LD, Jones L, Gardner MB, et al.: Vaccinia virus recombinants expressing chimeric proteins of human immunodeficiency virus and gamma interferon are attenuated for nude mice. Proc Natl Acad Sci USA 1992;89:3409-3413.
23. van Den Broek M, Bachmann MF, Kohler G, et al.: IL-4 and IL-10 antagonize IL-12-mediated protection against acute vaccinia virus infection with a limited role of IFN-gamma and nitric oxide synthetase 2. J Immunol 2000;164:371-378. (Pubitemid 30013011)
24. Liu VC, Wong LY, Jang T, et al.: Tumor evasion of the immune system by converting CD4+CD25-T cells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta. J Immunol 2007;178:2883-2892. (Pubitemid 46333166)
25. Wang H, Peters T, Sindrilaru A, et al.: TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis. J Clin Invest 2008;118: 2629-2639. (Pubitemid 351949790)
26. Edwards JR, Nyman JS, Lwin ST, et al.: Inhibition of TGF-beta signaling by 1D11 antibody treatment increases bone mass and quality in vivo. J Bone Miner Res 2008;25:2419-2426.
27. Gramaglia I, Jember A, Pippig SD, et al.: The OX40 costi-mulatory receptor determines the development of CD4 memory by regulating primary clonal expansion. J Immunol 2000;165:3043-3050.
28. Rogers PR, and Croft M: CD28, Ox-40, LFA-1, and CD4 modulation of Th1/Th2 differentiation is directly dependent on the dose of antigen. J Immunol 2000;164:2955-2963. (Pubitemid 30148953)
29. Salek-Ardakani S, Moutaftsi M, Crotty S, et al.: OX40 drives protective vaccinia virus-specific CD8 T cells. J Immunol 2008;181:7969-7976.
30. Xu R, Johnson AJ, Liggitt D, and Bevan MJ: Cellular and humoral immunity against vaccinia virus infection of mice. J Immunol 2004;172:6265-6271. (Pubitemid 38621233)
31. Cohen PE, Nishimura K, Zhu L, and Pollard JW: Macro-phages: important accessory cells for reproductive function. J Leukoc Biol 1999;66:765-772. (Pubitemid 29532038)
32. Suzuki T, Sasano H, Takaya R, et al.: Leukocytes in normal-cycling human ovaries: immunohistochemical distribution and characterization. Hum Reprod 1998;13:2186-2191. (Pubitemid 28425112)
33. Brannstrom M, and Norman RJ: Involvement of leukocytes and cytokines in the ovulatory process and corpus luteum function. Hum Reprod 1993;8:1762-1775. (Pubitemid 23299805)
34. Brannstrom M, Giesecke L, Moore IC, et al.: Leukocyte subpopulations in the rat corpus luteum during pregnancy and pseudopregnancy. Biol Reprod 1994;50:1161-1167. (Pubitemid 24116053)
35. Kurilla MG, Swaminathan S, Welsh RM, et al.: Effects of virally expressed interleukin-10 on vaccinia virus infection in mice. J Virol 1993;67:7623-7628. (Pubitemid 23343894)
36. Mendez-Samperio P, Hernandez M, and Ayala HE: Induction of transforming growth factor-beta 1 production in human cells by herpes simplex virus. J Interferon Cytokine Res 2000;20:273-280. (Pubitemid 30169738)
37. Kekow J, Wachsman W, McCutchan JA, et al.: Transforming growth factor beta and noncytopathic mechanisms of immunodeficiency in human immunodeficiency virus infection. Proc Natl Acad Sci USA 1990;87:8321-8325.
38. Thomas DA, and Massague J: TGF-beta directly targets cy-totoxic T cell functions during tumor evasion of immune surveillance. Cancer Cell 2005;8:369-380. (Pubitemid 41579832)
39. Huang S, Hendriks W, Althage A, et al.: Immune response in mice that lack the interferon-gamma receptor. Science 1993;259:1742-1745. (Pubitemid 23114659)
40. Karupiah G, Fredrickson TN, Holmes KL, et al.: Importance of interferons in recovery from mousepox. J Virol 1993; 67:4214-4226. (Pubitemid 23180748)
41. Lucin P, Pavic I, Polic B, et al.: Gamma interferon-dependent clearance of cytomegalovirus infection in salivary glands. J Virol 1992;66:1977-1984.
42. Lucchiari MA, Modolell M, Eichmann K, and Pereira CA: In vivo depletion of interferon-gamma leads to susceptibility of A/J mice to mouse hepatitis virus 3 infection. Im-munobiology 1992;185:475-482.
43. Schijns VE, Haagmans BL, Rijke EO, et al.: IFN-gamma receptor-deficient mice generate antiviral Th1-characteristic cytokine profiles but altered antibody responses. J Immunol 1994;153:2029-2037.
44. Graham MB, Dalton DK, Giltinan D, et al.: Response to influenza infection in mice with a targeted disruption in the interferon gamma gene. J Exp Med 1993;178:1725-1732. (Pubitemid 23318451)
45. Pires ES: Multiplicity of molecular and cellular targets in human ovarian autoimmunity: an update. J Assist Reprod Genet 2010;27:519-524.
46. Fenichel P, Sosset C, Barbarino-Monnier P, et al.: Prevalence, specificity and significance of ovarian antibodies during spontaneous premature ovarian failure. Hum Reprod 1997; 12:2623-2628. (Pubitemid 28031720)
47. Davies DH, McCausland MM, Valdez C, et al.: Vaccinia virus H3L envelope protein is a major target of neutralizing antibodies in humans and elicits protection against lethal challenge in mice. J Virol 2005;79:11724-11733. (Pubitemid 41279291)
48. Tscharke DC, Karupiah G, Zhou J, et al.: Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines. J Exp Med 2005; 201:95-104. (Pubitemid 40130087)
49. Moutaftsi M, Peters B, Pasquetto V, et al.: A consensus epi-tope prediction approach identifies the breadth of murine T(CD8 +)-cell responses to vaccinia virus. Nat Biotechnol 2006;24:817-819. (Pubitemid 44086622)
50. Moyron-Quiroz JE, McCausland MM, Kageyama R, et al.: The smallpox vaccine induces an early neutralizing IgM response. Vaccine 2009;28:140-147.