Inhibitory effect of glutamate release from rat cerebrocortical nerve terminals by α2 adrenoceptor agonist dexmedetomidine

European Journal of Pharmacology

Volumn 670, Issue 1, 2011, Pages 137-147

  Chiu, Kuan Ming ^a,b   Lin, Tzu Yu ^a,c   Lu, Cheng Wei ^a   Wang, Su Jane ^d,e  

^a FAR EASTERN MEMORIAL HOSPITAL   (Taiwan)

^b ORIENTAL INSTITUTE OF TECHNOLOGY   (Taiwan)

^c YUAN ZE UNIVERSITY   (Taiwan)

^d FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^e FU JEN CATHOLIC UNIVERSITY   (Taiwan)

Author keywords

2 adrenoceptor agonist; Dexmedetomidine; Glutamate release; Mitogen activated protein kinase; Synaptosome; Voltage dependent Ca 2+ channel

Indexed keywords

3 HYDROXYASPARTIC ACID; 4 AMINOPYRIDINE; ALPHA 2 ADRENERGIC RECEPTOR; BAFILOMYCIN A1; CALCIUM CHANNEL N TYPE; CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; CALCIUM ION; DEXMEDETOMIDINE; GLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; RYANODINE RECEPTOR; SYNAPSIN I;

ADULT ANIMAL; AMINO ACID TRANSPORT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN SYNAPTOSOME; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; DRUG EFFECT; DRUG MECHANISM; ENZYME PHOSPHORYLATION; INHIBITION KINETICS; MALE; MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RAT; SODIUM CALCIUM EXCHANGE; WESTERN BLOTTING;

4-AMINOPYRIDINE; ADRENERGIC ALPHA-2 RECEPTOR AGONISTS; ANIMALS; CALCIUM; CALCIUM CHANNELS, N-TYPE; CEREBRAL CORTEX; DEXMEDETOMIDINE; GLUTAMIC ACID; MALE; MAP KINASE SIGNALING SYSTEM; MEMBRANE POTENTIALS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-2; SYNAPSES; SYNAPTOSOMES;

EID: 80054729318     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.08.012     Document Type: Article

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