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Volumn 96, Issue 2, 2003, Pages 524-531

The effect of the α2-agonist dexmedetomidine and the N-methyl-D-aspartate antagonist S(+)-ketamine on the expression of apoptosis-regulating proteins after incomplete cerebral ischemia and reperfusion in rats

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS REGULATING PROTEIN; DEXMEDETOMIDINE; FENTANYL; ISOFLURANE; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NITROUS OXIDE; PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MDM2; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 0037302813     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-200302000-00041     Document Type: Article
Times cited : (230)

References (26)
  • 1
    • 0033735572 scopus 로고    scopus 로고
    • High-dose S(+)-ketamine improves neurological outcome following incomplete cerebral ischemia
    • Reeker W, Werner C, Möllenberg O, et al. High-dose S(+)-ketamine improves neurological outcome following incomplete cerebral ischemia. Can J Anaesth 2000;47:572-8.
    • (2000) Can J Anaesth , vol.47 , pp. 572-578
    • Reeker, W.1    Werner, C.2    Möllenberg, O.3
  • 2
    • 0027492005 scopus 로고
    • Interaction of catecholamines and nitrous oxide ventilation during incomplete brain ischemia in rats
    • Hoffman WE, Baughman VL, Albrecht RF. Interaction of catecholamines and nitrous oxide ventilation during incomplete brain ischemia in rats. Anesth Analg 1993;77:908-12.
    • (1993) Anesth Analg , vol.77 , pp. 908-912
    • Hoffman, W.E.1    Baughman, V.L.2    Albrecht, R.F.3
  • 3
    • 0025930833 scopus 로고
    • Dexmedetomidine improves neurologic outcome from incomplete ischemia in the rat
    • Hoffman WE, Kochs E, Werner C, et al. Dexmedetomidine improves neurologic outcome from incomplete ischemia in the rat. Anesthesiology 1991;75:328-32.
    • (1991) Anesthesiology , vol.75 , pp. 328-332
    • Hoffman, W.E.1    Kochs, E.2    Werner, C.3
  • 4
    • 0031053186 scopus 로고    scopus 로고
    • Monoamine-induced apoptotic neuronal cell death
    • Zilkha-Falb R, Ziv I, Nardi N, et al. Monoamine-induced apoptotic neuronal cell death. Cell Mol Neurobiol 1997;17:101-18.
    • (1997) Cell Mol Neurobiol , vol.17 , pp. 101-118
    • Zilkha-Falb, R.1    Ziv, I.2    Nardi, N.3
  • 5
    • 0033763403 scopus 로고    scopus 로고
    • Detection of high molecular weight DNA fragments characteristic of early stage apoptosis in cerebellar granule cells exposed to glutamate
    • Slagsvold HH, Marvik OJ, Eidem G, et al. Detection of high molecular weight DNA fragments characteristic of early stage apoptosis in cerebellar granule cells exposed to glutamate. Exp Brain Res 2000;135:173-8.
    • (2000) Exp Brain Res , vol.135 , pp. 173-178
    • Slagsvold, H.H.1    Marvik, O.J.2    Eidem, G.3
  • 6
    • 0030181799 scopus 로고    scopus 로고
    • Stimulation of N-methyl-D-aspartate receptors induces apoptosis in rat brain
    • Qin Z-H, Wang Y, Chase TN. Stimulation of N-methyl-D-aspartate receptors induces apoptosis in rat brain. Brain Res 1996;725:166-76.
    • (1996) Brain Res , vol.725 , pp. 166-176
    • Qin, Z.-H.1    Wang, Y.2    Chase, T.N.3
  • 7
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 8
    • 0022379447 scopus 로고
    • The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining
    • Tsujimoto Y, Gorham J, Cossman J, et al. The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining. Science 1985;229:1390-3.
    • (1985) Science , vol.229 , pp. 1390-1393
    • Tsujimoto, Y.1    Gorham, J.2    Cossman, J.3
  • 9
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltavi ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993;74:609-19.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltavi, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 10
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 1997;275:1132-6.
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 11
    • 0031036872 scopus 로고    scopus 로고
    • Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
    • Yang J, Liu X, Bhalla K, et al. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 1997;275:1129-32.
    • (1997) Science , vol.275 , pp. 1129-1132
    • Yang, J.1    Liu, X.2    Bhalla, K.3
  • 12
    • 0029950290 scopus 로고    scopus 로고
    • Bcl-2 inhibits the mitochondrial release of an apoptogenic protease
    • Susin SA, Zamzami N, Castedo M, et al. Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J Exp Med 1996;184:1331-41.
    • (1996) J Exp Med , vol.184 , pp. 1331-1341
    • Susin, S.A.1    Zamzami, N.2    Castedo, M.3
  • 13
    • 0029906828 scopus 로고    scopus 로고
    • Bax-induced cell death may not require interleukin 1β-converting enzyme-like protease
    • Xiang J, Chao DT, Korsmeyer SJ. Bax-induced cell death may not require interleukin 1β-converting enzyme-like protease. Proc Natl Acad Sci U S A 1996;93:14559-63.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 14559-14563
    • Xiang, J.1    Chao, D.T.2    Korsmeyer, S.J.3
  • 14
    • 0031821795 scopus 로고    scopus 로고
    • Potentiation of murine astrocyte antioxidant defence by bcl-2: Protection in part reflects elevated glutathione levels
    • Papadopoulos MC, Koumenis IL, Xu L, Giffard RG. Potentiation of murine astrocyte antioxidant defence by bcl-2: protection in part reflects elevated glutathione levels. Eur J Neurosci 1998;10: 1252-60.
    • (1998) Eur J Neurosci , vol.10 , pp. 1252-1260
    • Papadopoulos, M.C.1    Koumenis, I.L.2    Xu, L.3    Giffard, R.G.4
  • 15
    • 0032997952 scopus 로고    scopus 로고
    • Bcl-2 transduction, using a herpes simplex virus amplicon, protects hippocampal neurons from transient global ischemia
    • Antonawich FJ, Federoff HJ, Davis JN. Bcl-2 transduction, using a herpes simplex virus amplicon, protects hippocampal neurons from transient global ischemia. Exp Neurol 1999;156:130-7.
    • (1999) Exp Neurol , vol.156 , pp. 130-137
    • Antonawich, F.J.1    Federoff, H.J.2    Davis, J.N.3
  • 17
    • 0000064578 scopus 로고    scopus 로고
    • Altered expression of Bcl-2, Bcl-x, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following cerebral artery occlusion in rats
    • Gillardon F, Lenz C, Waschke KF, et al. Altered expression of Bcl-2, Bcl-x, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following cerebral artery occlusion in rats. Mol Brain Res 1996;40:254-60.
    • (1996) Mol Brain Res , vol.40 , pp. 254-260
    • Gillardon, F.1    Lenz, C.2    Waschke, K.F.3
  • 18
    • 0028335717 scopus 로고
    • Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo
    • Miyashita T, Krajewski S, Krajewska M, et al. Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene 1994;9:1799-805.
    • (1994) Oncogene , vol.9 , pp. 1799-1805
    • Miyashita, T.1    Krajewski, S.2    Krajewska, M.3
  • 19
    • 0028238213 scopus 로고
    • Immediate early up-regulation of bax expression by p53 but not TGFb1: A paradigm for distinct apoptotic pathways
    • Selvakumaran M, Lin HK, Miyashita T, et al. Immediate early up-regulation of bax expression by p53 but not TGFb1: a paradigm for distinct apoptotic pathways. Oncogene 1994;9:1791-8.
    • (1994) Oncogene , vol.9 , pp. 1791-1798
    • Selvakumaran, M.1    Lin, H.K.2    Miyashita, T.3
  • 20
    • 0030884358 scopus 로고    scopus 로고
    • Apoptosis and protein expression after focal cerebral ischemia in rat
    • Li Y, Chopp M, Powers C, Jiang N. Apoptosis and protein expression after focal cerebral ischemia in rat. Brain Res 1997; 765:301-12.
    • (1997) Brain Res , vol.765 , pp. 301-312
    • Li, Y.1    Chopp, M.2    Powers, C.3    Jiang, N.4
  • 21
    • 0033059025 scopus 로고    scopus 로고
    • The tumor-suppressor gene, p53, is induced in injured brain regions following experimental traumatic brain injury
    • Napieralski JA, Raghupathi R, McIntosh TK. The tumor-suppressor gene, p53, is induced in injured brain regions following experimental traumatic brain injury. Mol Brain Res 1999; 71:78-86.
    • (1999) Mol Brain Res , vol.71 , pp. 78-86
    • Napieralski, J.A.1    Raghupathi, R.2    McIntosh, T.K.3
  • 22
    • 0030840777 scopus 로고    scopus 로고
    • p53-knockout mice are protected against the long-term effects of methamphetamine on dopaminergic terminals and cell bodies
    • Hirata H, Cadet JL. p53-knockout mice are protected against the long-term effects of methamphetamine on dopaminergic terminals and cell bodies. J Neurochem 1997;69:780-90.
    • (1997) J Neurochem , vol.69 , pp. 780-790
    • Hirata, H.1    Cadet, J.L.2
  • 23
    • 0035943738 scopus 로고    scopus 로고
    • Neurons are protected from excitotoxic death by p53 antisense oligonucleotides delivered in anionic liposomes
    • Lakkaraju A, Dubinsky JM, Low WC, Rahman Y-E. Neurons are protected from excitotoxic death by p53 antisense oligonucleotides delivered in anionic liposomes. J Biol Chem 2001;276: 32000-7.
    • (2001) J Biol Chem , vol.276 , pp. 32000-32007
    • Lakkaraju, A.1    Dubinsky, J.M.2    Low, W.C.3    Rahman, Y.-E.4
  • 24
    • 0026649648 scopus 로고
    • The Mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • Momand J, Zambetti GP, Olson DC, et al. The Mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 1992;69:1237-45.
    • (1992) Cell , vol.69 , pp. 1237-1245
    • Momand, J.1    Zambetti, G.P.2    Olson, D.C.3
  • 25
    • 0027325132 scopus 로고
    • Oncoprotein Mdm-2 conceals the activation domain of tumor suppressor p53
    • Oliner JD, Pietenpol JA, Thiagalingam S, et al. Oncoprotein Mdm-2 conceals the activation domain of tumor suppressor p53. Nature 1993;362:857-60.
    • (1993) Nature , vol.362 , pp. 857-860
    • Oliner, J.D.1    Pietenpol, J.A.2    Thiagalingam, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.