Synthesis and in vitro antiproliferative activity of novel (4-chloro- and 4-acyloxy-2-butynyl)thioquinolines

Medicinal Chemistry Research

Volumn 20, Issue 8, 2011, Pages 1402-1410

  Boryczka, Stanislaw ^a   Mól, Wojciech ^a   Milczarek, Magdalena ^b   Wietrzyk, Joanna ^b   Bȩbenek, Ewa ^a  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

^b INSTITUTE OF IMMUNOLOGY AND EXPERIMENTAL THERAPY   (Poland)

Author keywords

(4 Acyloxy 2 butynyl)thioquinolines; (4 Chloro 2 butynyl)thioquinolines; Acetylenic thioquinolines; Antiproliferative activity

Indexed keywords

(4 ACYLOXY 2 BUTYNYL)THIOQUINOLINE DERIVATIVE; (4 CHLORO 2 BUTYNYL)THIOQUINOLINE DERIVATIVE; 4 (4 BENZOYLOXY 2 BUTYNYLSELENO) 3 METHYLTHIOQUINOLINE; 4 (4 BENZOYLOXY 2 BUTYNYLTHIO) 3 METHYLTHIOQUINOLINE; 4 (4 CINNAMOYLOXY 2 BUTYNYLSELENO) 3 METHYLTHIOQUINOLINE; 4 (4 CINNAMOYLOXY 2 BUTYNYLTHIO) 3 METHYLTHIOQUINOLINE; 4 (4 ETHOXYCARBONYLOXY 2 BUTYNYLTHIO) 3 METHYLTHIOQUINOLINE; 4 (4 HYDROPHTHALOYLOXY 2 BUTYNYLSELENO) 3 METHYLTHIOQUINOLINE; 4 (4 HYDROPHTHALOYLOXY 2 BUTYNYLTHIO) 3 METHYLTHIOQUINOLINE; 4 (4 HYDROXY 2 BUTYNYLSELENO) 3 METHYLTHIOQUINOLINE; 4 (4 HYDROXY 2 BUTYNYLTHIO) 3 METHYLTHIOQUINOLINE; 4 CHLORO 3 (4 CHLORO 2 BUTYNYLTHIO)QUINOLINE; 4 CHLORO 3 (4 HYDROXY 2 BUTYNYLTHIO)QUINOLINE; ANTINEOPLASTIC AGENT; CISPLATIN; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

EID: 80054719511     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-010-9495-y     Document Type: Article

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