Dietary flaxseed protects against lung ischemia reperfusion injury via inhibition of apoptosis and inflammation in a murine model

Journal of Surgical Research

Volumn 171, Issue 1, 2011, Pages

  Razi, Syed S ^a   Latif, Mohammed J ^a   Li, Xiaogui ^a   Afthinos, John N ^a   Ippagunta, Nikalesh ^a   Schwartz, Gary ^a   Sagalovich, Daniel ^a   Belsley, Scott J ^a   Connery, Cliff P ^a   Jour, George ^a   Christofidou Solomidou, Melpo ^b   Bhora, Faiz Y ^a  

^a Columbia University College of Physicians and Surgeons ^*  (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

apoptosis; flaxseed; inflammation; ischemia reperfusion injury; oxidative stress

Indexed keywords

ANTIOXIDANT; CASPASE 2; CASPASE 3; CASPASE 8; CASPASE 9; HEME OXYGENASE 1; INTERLEUKIN 1BETA CONVERTING ENZYME; PROCASPASE 3; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DIET THERAPY; FEMALE; INFLAMMATORY INFILTRATE; ISCHEMIA; LINSEED; LUNG HOMOGENATE; LUNG INJURY; LUNG ISCHEMIA REPERFUSION INJURY; LUNG LAVAGE; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY;

ACUTE LUNG INJURY; ANIMAL FEED; ANIMALS; ANTIOXIDANTS; APOPTOSIS; BRONCHOALVEOLAR LAVAGE FLUID; CASPASE 3; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; FEMALE; FLAX; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; PNEUMONIA; REPERFUSION INJURY; RNA, MESSENGER;

EID: 80054708619     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2011.06.017     Document Type: Article

References (47)

1. H. Mal, M. Dehoux, and C. Sleiman Early release of proinflammatory cytokines after lung transplantation Chest 113 1998 645
2. D.A. Parks, G.B. Bulkley, and D.N. Granger Role of oxygen free radicals in shock, ischemia, and organ preservation Surgery 94 1983 428
3. M. de Perrot, M. Liu, and T.K. Waddell Ischemia-reperfusion-induced lung injury Am J Respir Crit Care Med 167 2003 490
4. C.E. Cross, B. Halliwell, and E.T. Borish Oxygen radicals and human disease Ann Intern Med 107 1987 526
5. G.A. Fantini, and T. Yoshioka Deferoxamine prevents lipid peroxidation and attenuates reoxygenation injury in postischemic skeletal muscle Am J Physiol 264 1993 H1953
6. D.N. Granger, J.M. McCord, and D.A. Parks Xanthine oxidase inhibitors attenuate ischemia-induced vascular permeability changes in the cat intestine Gastroenterology 90 1986 80
7. T. Nguyen, D. Brunson, and C.L. Crespi DNA damage and mutation in human cells exposed to nitric oxide in vitro Proc Natl Acad Sci U S A 89 1992 3030
8. S. Kumar, and N.L. Harvey Role of multiple cellular proteases in the execution of programmed cell death FEBS Lett 375 1995 169
9. M.L. Entman, L. Michael, and R.D. Rossen Inflammation in the course of early myocardial ischemia FASEB J 5 1991 2529
10. W. Zhou, M.O. McCollum, and B.A. Levine Inflammation and platelet-activating factor production during hepatic ischemia/reperfusion Hepatology 16 1992 1236
11. H. Steller Mechanisms and genes of cellular suicide Science 267 1995 1445
12. H.R. Horvitz Genetic control of programmed cell death in the nematode Caenorhabditis elegans Cancer Res 59 7 Suppl 1999 1701s
13. P. Kinniry, Y. Amrani, and A. Vachani Dietary flaxseed supplementation ameliorates inflammation and oxidative tissue damage in experimental models of acute lung injury in mice J Nutr 136 2006 1545
14. J.C. Lee, F. Bhora, and J. Sun Dietary flaxseed enhances antioxidant defenses and is protective in a mouse model of lung ischemia-reperfusion injury Am J Physiol Lung Cell Mol Physiol 294 2008 L255
15. J.C. Lee, R. Krochak, and A. Blouin Dietary flaxseed prevents radiation-induced oxidative lung damage, inflammation and fibrosis in a mouse model of thoracic radiation injury Cancer Biol Ther 8 2009 47
16. A.P. Simopoulos Omega-3 fatty acids in inflammation and autoimmune diseases J Am Coll Nutr 21 2002 495
17. J.Y. Xue, G.T. Liu, and H.L. Wei Antioxidant activity of two dibenzocyclooctene lignans on the aged and ischemic brain in rats Free Radic Biol Med 12 1992 127
18. L.E. Donnelly, R. Newton, and G.E. Kennedy Anti-inflammatory effects of resveratrol in lung epithelial cells: Molecular mechanisms Am J Physiol Lung Cell Mol Physiol 287 2004 L774
19. J.C. Lee, P.A. Kinniry, and E. Arguiri Dietary curcumin increases antioxidant defenses in lung, ameliorates radiation-induced pulmonary fibrosis, and improves survival in mice Radiat Res 173 2010 590
20. S.Q. Shen, Y. Zhang, and J.J. Xiang Protective effect of curcumin against liver warm ischemia/reperfusion injury in rat model is associated with regulation of heat shock protein and antioxidant enzymes World J Gastroenterol 13 2007 1953
21. P. Bansal, S.K. Gupta, and S.K. Ojha Cardioprotective effect of lycopene in the experimental model of myocardial ischemia-reperfusion injury Mol Cell Biochem 289 2006 1
22. H.Y. Yoon, N.I. Kang, and H.K. Lee Sulforaphane protects kidneys against ischemia-reperfusion injury through induction of the Nrf2-dependent phase 2 enzyme Biochem Pharmacol 75 2008 2214
23. P.J. Elliott, and M. Jirousek Sirtuins: Novel targets for metabolic disease Curr Opin Investig Drugs 9 2008 371
24. S. Kawanishi, S. Oikawa, and M. Murata Evaluation for safety of antioxidant chemopreventive agents Antioxid Redox Signal 7 2005 1728
25. S. Fischer, A.A. Maclean, and M. Liu Dynamic changes in apoptotic and necrotic cell death correlate with severity of ischemia-reperfusion injury in lung transplantation Am J Respir Crit Care Med 162 2000 1932
26. F. Eefting, B. Rensing, and J. Wigman Role of apoptosis in reperfusion injury Cardiovasc Res 61 2004 414
27. M.A. Daemen, B. de Vries, and W.A. Buurman Apoptosis and inflammation in renal reperfusion injury Transplantation 73 2002 1693
28. M.A. Daemen, C. Van't Veer, and G. Denecker Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation J Clin Invest 104 1999 541
29. S.T. Loubele, C.A. Spek, and P. Leenders Activated protein C protects against myocardial ischemia/reperfusion injury via inhibition of apoptosis and inflammation Arterioscler Thromb Vasc Biol 29 2009 1087
30. E.A. Dumont, L. Hofstra, and W.L. van Heerde Cardiomyocyte death induced by myocardial ischemia and reperfusion: Measurement with recombinant human annexin-V in a mouse model Circulation 102 2000 1564
31. A.D. Edwards, and H. Mehmet Apoptosis in perinatal hypoxic-ischaemic cerebral damage Neuropathol Appl Neurobiol 22 1996 494
32. J. Honkaniemi, S.M. Massa, and M. Breckinridge Global ischemia induces apoptosis-associated genes in hippocampus Brain Res Mol Brain Res 42 1996 79
33. S. Motoyama, Y. Minamiya, and S. Saito Hydrogen peroxide derived from hepatocytes induces sinusoidal endothelial cell apoptosis in perfused hypoxic rat liver Gastroenterology 114 1998 153
34. H. Sasaki, T. Matsuno, and N. Tanaka Activation of apoptosis during the reperfusion phase after rat liver ischemia Transplant Proc 28 1996 1908
35. M. Schumer, M.C. Colombel, and I.S. Sawczuk Morphologic, biochemical, and molecular evidence of apoptosis during the reperfusion phase after brief periods of renal ischemia Am J Pathol 140 1992 831
36. P. Anversa, W. Cheng, and Y. Liu Apoptosis and myocardial infarction Basic Res Cardiol 93 Suppl 3 1998 8
37. M.K. Kwak, N. Wakabayashi, and K. Itoh Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival J Biol Chem 278 2003 8135
38. M.O. Leonard, N.E. Kieran, and K. Howell Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia-reperfusion injury FASEB J 20 2006 2624
39. Y.Y. Lee-Hilz, A.M. Boerboom, and A.H. Westphal Pro-oxidant activity of flavonoids induces EpRE-mediated gene expression Chem Res Toxicol 19 2006 1499
40. K. Struijs, J.P. Vincken, and R. Verhoef The flavonoid herbacetin diglucoside as a constituent of the lignan macromolecule from flaxseed hulls Phytochemistry 68 2007 1227
41. H. Ahsan, N. Parveen, and N.U. Khan Pro-oxidant, antioxidant and cleavage activities on DNA of curcumin and its derivatives demethoxycurcumin and bisdemethoxycurcumin Chem Biol Interact 121 1999 161
42. M. Christofidou-Solomidou, A. Scherpereel, and R. Wiewrodt PECAM-directed delivery of catalase to endothelium protects against pulmonary vascular oxidative stress Am J Physiol Lung Cell Mol Physiol 285 2003 L283
43. I. Inci, W. Zhai, and S. Arni N-acetylcysteine attenuates lung ischemia-reperfusion injury after lung transplantation Ann Thorac Surg 84 2007 240
44. H. Liu, L. Liu, and G.A. Visner Nonviral gene delivery with indoleamine 2,3-dioxygenase targeting pulmonary endothelium protects against ischemia-reperfusion injury Am J Transplant 7 2007 2291
45. V.V. Shuvaev, M. Christofidou-Solomidou, and F. Bhora Targeted detoxification of selected reactive oxygen species in the vascular endothelium J Pharmacol Exp Ther 331 2009 404
46. Z.R. Healy, N.H. Lee, and X. Gao Divergent responses of chondrocytes and endothelial cells to shear stress: Cross-talk among COX-2, the phase 2 response, and apoptosis Proc Natl Acad Sci U S A 102 2005 14010
47. P.D. Nesbitt, Y. Lam, and L.U. Thompson Human metabolism of mammalian lignan precursors in raw and processed flaxseed Am J Clin Nutr 69 1999 549