Nonviral gene delivery with indoleamine 2,3-dioxygenase targeting pulmonary endothelium protects against ischemia-reperfusion injury

American Journal of Transplantation

Volumn 7, Issue 10, 2007, Pages 2291-2300

  Liu, H ^a   Liu, L ^b   Visner, G A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Acute graft failure; Endothelial dysfunction; Gene therapy; Ischemia reperfusion injury; Lung transplantation; Mitochondria; Oxidative stress

Indexed keywords

ENDOTHELIN 1; INDOLEAMINE 2,3 DIOXYGENASE; POLYETHYLENEIMINE; POLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DIRECTED ENZYME PRODRUG THERAPY; APOPTOSIS; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; EXTRAVASATION; HISTOLOGY; LEUKOCYTE; LUNG ENDOTHELIUM; LUNG INJURY; LUNG TRANSPLANTATION; MALE; MITOCHONDRION; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; TRANSGENE; ULTRASTRUCTURE;

ANIMALS; BLOOD UREA NITROGEN; ENDOTHELIUM, VASCULAR; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; LUNG TRANSPLANTATION; MALE; PLASMIDS; POLYMERASE CHAIN REACTION; PULMONARY CIRCULATION; RATS; RATS, INBRED LEW; REPERFUSION INJURY; TRANSFECTION;

EID: 34548301624     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2007.01942.x     Document Type: Article

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