Intermittent hypoxia augments pulmonary vascular smooth muscle reactivity to NO: Regulation by reactive oxygen species

Journal of Applied Physiology

Volumn 111, Issue 4, 2011, Pages 980-988

  Norton, Charles E ^a   Jernigan, Nikki L ^a   Kanagy, Nancy L ^a   Walker, Benjimen R ^a   Resta, Thomas C ^a  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

Author keywords

Endothelial nitric oxide synthase; Protein kinase G; Pulmonary hypertension; Sleep apnea; Superoxide anion

Indexed keywords

3 NITROTYROSINE; 3-NITROTYROSINE; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; DRUG DERIVATIVE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIUM DERIVED RELAXING FACTOR; IONOMYCIN; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE; NITRIC OXIDE DONOR; NOS3 PROTEIN, RAT; REACTIVE OXYGEN METABOLITE; SCAVENGER; SUPEROXIDE; TIRON; TYROSINE;

ANIMAL; ANOXIA; ARTICLE; DRUG ANTAGONISM; DRUG EFFECT; HEART RIGHT VENTRICLE HYPERTROPHY; HYPOCAPNIA; LUNG; MALE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; POLYCYTHEMIA; PULMONARY ARTERY; RAT; VASCULAR SMOOTH MUSCLE; VASODILATATION; WISTAR RAT;

1,2-DIHYDROXYBENZENE-3,5-DISULFONIC ACID DISODIUM SALT; ANIMALS; ANOXIA; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; ENDOTHELIUM-DEPENDENT RELAXING FACTORS; FREE RADICAL SCAVENGERS; HYPERTROPHY, RIGHT VENTRICULAR; HYPOCAPNIA; IONOMYCIN; LUNG; MALE; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; NITRIC OXIDE DONORS; NITRIC OXIDE SYNTHASE TYPE III; POLYCYTHEMIA; PULMONARY ARTERY; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; S-NITROSO-N-ACETYLPENICILLAMINE; SUPEROXIDES; TYROSINE; VASODILATION;

EID: 80054697580     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01286.2010     Document Type: Article

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