Lipids, curvature stress, and the action of lipid prodrugs: Free fatty acids and lysolipid enhancement of drug transport across liposomal membranes

Biochimie

Volumn 94, Issue 1, 2012, Pages 2-10

  Jespersen, Henrik ^a   Andersen, Jonas H ^a   Ditzel, Henrik J ^a,b   Mouritsen, Ole G ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b ODENSE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Curvature stress; Doxorubicin; Drug delivery; Free fatty acids; Lipids; Liposome; Lysolipids; Permeability

Indexed keywords

CHOLESTEROL; DOXORUBICIN; FATTY ACID; LIPID; LIPOSOME; LYSOLIPID; PHOSPHOLIPASE A2; PRODRUG; UNCLASSIFIED DRUG;

ARTICLE; CANCER TISSUE; CONTROLLED STUDY; DRUG PENETRATION; DRUG RELEASE; DRUG TRANSPORT; ENZYME RELEASE; FLUORESCENCE ANALYSIS; LIPID BILAYER; LIPID MEMBRANE; LIPOSOMAL DELIVERY; MEMBRANE PERMEABILITY; QUANTITATIVE ANALYSIS;

DOXORUBICIN; FATTY ACIDS, NONESTERIFIED; LIPIDS; LIPOSOMES; MEMBRANES, ARTIFICIAL; PRODRUGS;

EID: 80054687304     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2011.07.029     Document Type: Article

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