-
1
-
-
60749086521
-
Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers
-
Ahlquist T, Lind G, Costa V et al (2008). Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers. Mol Cancer 7: 94-99.
-
(2008)
Mol Cancer
, vol.7
, pp. 94-99
-
-
Ahlquist, T.1
Lind, G.2
Costa, V.3
-
2
-
-
33745634864
-
Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer
-
Ai L, Tao Q, Zhong S et al (2006). Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer. Carcinogenesis 27: 1341-1348.
-
(2006)
Carcinogenesis
, vol.27
, pp. 1341-1348
-
-
Ai, L.1
Tao, Q.2
Zhong, S.3
-
3
-
-
69349084287
-
Methylation of p16 CpG island associated with malignant progression of oral epithelial dysplasia: a prospective cohort study
-
Cao J, Zhou J, Gao Y et al (2009). Methylation of p16 CpG island associated with malignant progression of oral epithelial dysplasia: a prospective cohort study. Clin Cancer Res 15: 5178-5183.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5178-5183
-
-
Cao, J.1
Zhou, J.2
Gao, Y.3
-
4
-
-
34250310905
-
The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas
-
Chan S, Cui Y, van Hasselt A et al (2007). The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas. Lab Invest 87: 644-650.
-
(2007)
Lab Invest
, vol.87
, pp. 644-650
-
-
Chan, S.1
Cui, Y.2
van Hasselt, A.3
-
5
-
-
77950151788
-
Hypermethylation downregulates Runx3 gene expression and its restoration suppresses gastric epithelial cell growth by inducing p27 and caspase3 in human gastric cancer
-
Chen W, Gao N, Shen Y, Cen J (2010). Hypermethylation downregulates Runx3 gene expression and its restoration suppresses gastric epithelial cell growth by inducing p27 and caspase3 in human gastric cancer. J Gastroenterol Hepatol 25: 823-831.
-
(2010)
J Gastroenterol Hepatol
, vol.25
, pp. 823-831
-
-
Chen, W.1
Gao, N.2
Shen, Y.3
Cen, J.4
-
6
-
-
36949027736
-
Epigenetic alteration of the Wnt inhibitory factor-1 promoter occurs early in the carcinogenesis of Barrett's esophagus
-
Clément G, Guilleret I, He B et al (2008). Epigenetic alteration of the Wnt inhibitory factor-1 promoter occurs early in the carcinogenesis of Barrett's esophagus. Cancer Sci 99: 46-53.
-
(2008)
Cancer Sci
, vol.99
, pp. 46-53
-
-
Clément, G.1
Guilleret, I.2
He, B.3
-
7
-
-
63549104387
-
Frequent inactivation of RUNX3 by promoter hypermethylation and protein mislocalization in oral squamous cell carcinomas
-
Gao F, Huang C, Lin M et al (2009). Frequent inactivation of RUNX3 by promoter hypermethylation and protein mislocalization in oral squamous cell carcinomas. J Cancer Res Clin Oncol 135: 739-747.
-
(2009)
J Cancer Res Clin Oncol
, vol.135
, pp. 739-747
-
-
Gao, F.1
Huang, C.2
Lin, M.3
-
8
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
Herman J, Baylin S (2003). Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 349: 2042-2054.
-
(2003)
N Engl J Med
, vol.349
, pp. 2042-2054
-
-
Herman, J.1
Baylin, S.2
-
9
-
-
0029843950
-
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands
-
Herman J, Graff J, Myohanen S et al (1996). Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 93: 9821-9826.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9821-9826
-
-
Herman, J.1
Graff, J.2
Myohanen, S.3
-
10
-
-
24744470103
-
RUNX3, a novel tumor suppressor, is frequently inactivated in gastric cancer by protein mislocalization
-
Ito K, Liu Q, Salto-Tellez M et al (2005). RUNX3, a novel tumor suppressor, is frequently inactivated in gastric cancer by protein mislocalization. Cancer Res 65: 7743-7750.
-
(2005)
Cancer Res
, vol.65
, pp. 7743-7750
-
-
Ito, K.1
Liu, Q.2
Salto-Tellez, M.3
-
11
-
-
50649086570
-
RUNX3 attenuates b-catenin/T cell factors in intestinal tumorigenesis
-
Ito K, Lim A, Salto-Tellez M et al (2008). RUNX3 attenuates b-catenin/T cell factors in intestinal tumorigenesis. Cancer Cell 14: 226-237.
-
(2008)
Cancer Cell
, vol.14
, pp. 226-237
-
-
Ito, K.1
Lim, A.2
Salto-Tellez, M.3
-
12
-
-
27744568076
-
Mutations of the APC, beta-catenin, and axin 1 genes and cytoplasmic accumulation of beta-catenin in oral squamous cell carcinoma
-
Iwai S, Katagiri W, Kong C et al (2005). Mutations of the APC, beta-catenin, and axin 1 genes and cytoplasmic accumulation of beta-catenin in oral squamous cell carcinoma. J Cancer Res Clin Oncol 13: 773-782.
-
(2005)
J Cancer Res Clin Oncol
, vol.13
, pp. 773-782
-
-
Iwai, S.1
Katagiri, W.2
Kong, C.3
-
13
-
-
27144524894
-
RUNX3 inactivation by point mutations and aberrant DNA methylation in bladder tumors
-
Kim W, Kim E, Jeong P et al (2005). RUNX3 inactivation by point mutations and aberrant DNA methylation in bladder tumors. Cancer Res 65: 9347-9354.
-
(2005)
Cancer Res
, vol.65
, pp. 9347-9354
-
-
Kim, W.1
Kim, E.2
Jeong, P.3
-
14
-
-
79251614031
-
Oncogenic role of RUNX3 in head and neck cancer
-
Kudo Y, Tsunematsu T, Takata T (2011). Oncogenic role of RUNX3 in head and neck cancer. J Cell Biochem 112: 387-393.
-
(2011)
J Cell Biochem
, vol.112
, pp. 387-393
-
-
Kudo, Y.1
Tsunematsu, T.2
Takata, T.3
-
15
-
-
33746121227
-
RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer
-
Lau Q, Raja E, Salto-Tellez M et al (2006). RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer. Cancer Res 66: 6512-6520.
-
(2006)
Cancer Res
, vol.66
, pp. 6512-6520
-
-
Lau, Q.1
Raja, E.2
Salto-Tellez, M.3
-
16
-
-
70349656779
-
Aberrant methylation of APC, MGMT, RASSF2A, and Wif-1 genes in plasma as a biomarker for early detection of colorectal cancer
-
Lee B, Lee E, Jung E et al (2009). Aberrant methylation of APC, MGMT, RASSF2A, and Wif-1 genes in plasma as a biomarker for early detection of colorectal cancer. Clin Cancer Res 15: 6185-6191.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6185-6191
-
-
Lee, B.1
Lee, E.2
Jung, E.3
-
17
-
-
47249111724
-
Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung
-
Licchesi J, Westra W, Hooker C et al (2008). Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung. Carcinogenesis 29: 895-904.
-
(2008)
Carcinogenesis
, vol.29
, pp. 895-904
-
-
Licchesi, J.1
Westra, W.2
Hooker, C.3
-
18
-
-
31444455766
-
Wnt signaling activation and WIF-1 silencing in nasopharyngeal cancer cell lines
-
Lin YC, You L, Xu Z et al (2006). Wnt signaling activation and WIF-1 silencing in nasopharyngeal cancer cell lines. Biochem Biophys Res Commun 341: 635-640.
-
(2006)
Biochem Biophys Res Commun
, vol.341
, pp. 635-640
-
-
Lin, Y.C.1
You, L.2
Xu, Z.3
-
19
-
-
0035013507
-
A possible role for the WNT-1 pathway in oral carcinogenesis
-
Lo Muzio L (2001). A possible role for the WNT-1 pathway in oral carcinogenesis. Crit Rev Oral Biol Med 12: 152-165.
-
(2001)
Crit Rev Oral Biol Med
, vol.12
, pp. 152-165
-
-
Lo Muzio, L.1
-
20
-
-
36849052340
-
Promoter hypermethylation of the RUNX3 gene in esophageal squamous cell carcinoma
-
Long C, Yin B, Lu Q et al (2007). Promoter hypermethylation of the RUNX3 gene in esophageal squamous cell carcinoma. Cancer Invest 25: 685-690.
-
(2007)
Cancer Invest
, vol.25
, pp. 685-690
-
-
Long, C.1
Yin, B.2
Lu, Q.3
-
21
-
-
70350044048
-
Towards targeted epigenetic therapy of cancer
-
Magic Z, Supic G, Brankovic-Magic M (2009). Towards targeted epigenetic therapy of cancer. J BUON 14(Suppl 1): S79-S88.
-
(2009)
J BUON
, vol.14
, Issue.SUPPL. 1
-
-
Magic, Z.1
Supic, G.2
Brankovic-Magic, M.3
-
22
-
-
3142679453
-
Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer
-
Mazieres J, He B, You L et al (2004). Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer. Cancer Res 64: 4717-4720.
-
(2004)
Cancer Res
, vol.64
, pp. 4717-4720
-
-
Mazieres, J.1
He, B.2
You, L.3
-
23
-
-
0034326238
-
Predicting lung cancer by detecting aberrant promoter methylation in sputum
-
Palmisano W, Divine K, Saccomanno G et al (2000). Predicting lung cancer by detecting aberrant promoter methylation in sputum. Cancer Res 60: 5954-5958.
-
(2000)
Cancer Res
, vol.60
, pp. 5954-5958
-
-
Palmisano, W.1
Divine, K.2
Saccomanno, G.3
-
24
-
-
77957374553
-
WNT pathway in oral cancer: epigenetic inactivation of WNT-inhibitors
-
Pannone G, Bufo P, Santoro A et al (2010). WNT pathway in oral cancer: epigenetic inactivation of WNT-inhibitors. Oncol Rep 24: 1035-1041.
-
(2010)
Oncol Rep
, vol.24
, pp. 1035-1041
-
-
Pannone, G.1
Bufo, P.2
Santoro, A.3
-
25
-
-
78651313568
-
Promoter CpG island hypermethylation during breast cancer progression
-
Park S, Kwon H, Lee H et al (2011). Promoter CpG island hypermethylation during breast cancer progression. Virchows Arch 458: 73-84.
-
(2011)
Virchows Arch
, vol.458
, pp. 73-84
-
-
Park, S.1
Kwon, H.2
Lee, H.3
-
26
-
-
4444323767
-
Cloning and characterization of the promoter of human Wnt inhibitory factor-1
-
Reguart N, He B, Xu Z et al (2004). Cloning and characterization of the promoter of human Wnt inhibitory factor-1. Biochem Biophys Res Commun 323: 229-234.
-
(2004)
Biochem Biophys Res Commun
, vol.323
, pp. 229-234
-
-
Reguart, N.1
He, B.2
Xu, Z.3
-
27
-
-
0037179894
-
Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas
-
Rhee C, Sen M, Lu D et al (2002). Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas. Oncogene 21: 6598-6605.
-
(2002)
Oncogene
, vol.21
, pp. 6598-6605
-
-
Rhee, C.1
Sen, M.2
Lu, D.3
-
28
-
-
80054070012
-
Cell alterations and molecular mechanisms in oral carcinogenesis
-
Romana PG (2010) Cell alterations and molecular mechanisms in oral carcinogenesis. Int J Oral Maxillofac Surg doi:.
-
(2010)
Int J Oral Maxillofac Surg
-
-
Romana, P.G.1
-
29
-
-
39449086075
-
Differential roles of p16INK4A and p14ARF genes in prognosis of oral carcinoma
-
Sailasree R, Abhilash A, Sathyan K, Nalinakumari K, Thomas S, Kannan S (2008). Differential roles of p16INK4A and p14ARF genes in prognosis of oral carcinoma. Cancer Epidemiol Biomarkers Prev 17: 414-420.
-
(2008)
Cancer Epidemiol Biomarkers Prev
, vol.17
, pp. 414-420
-
-
Sailasree, R.1
Abhilash, A.2
Sathyan, K.3
Nalinakumari, K.4
Thomas, S.5
Kannan, S.6
-
30
-
-
33845513110
-
RUNX3 protein is overexpressed in human basal cell carcinomas
-
Salto-Tellez M, Peh BK, Ito K et al (2006). RUNX3 protein is overexpressed in human basal cell carcinomas. Oncogene 25: 7646-7649.
-
(2006)
Oncogene
, vol.25
, pp. 7646-7649
-
-
Salto-Tellez, M.1
Peh, B.K.2
Ito, K.3
-
31
-
-
21244467485
-
Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk
-
Schulmann K, Sterian A, Berki A et al (2005). Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk. Oncogene 24: 4138-4148.
-
(2005)
Oncogene
, vol.24
, pp. 4138-4148
-
-
Schulmann, K.1
Sterian, A.2
Berki, A.3
-
32
-
-
68949221111
-
Oral squamous cell carcinoma: overview of current understanding of aetiopathogenesis and clinical implications
-
Scully C, Bagan J (2009). Oral squamous cell carcinoma: overview of current understanding of aetiopathogenesis and clinical implications. Oral Dis 15: 388-399.
-
(2009)
Oral Dis
, vol.15
, pp. 388-399
-
-
Scully, C.1
Bagan, J.2
-
33
-
-
30544444626
-
The epigenetics of oral cancer
-
Shaw R (2006). The epigenetics of oral cancer. Int J Oral Maxillofac Surg 35: 101-108.
-
(2006)
Int J Oral Maxillofac Surg
, vol.35
, pp. 101-108
-
-
Shaw, R.1
-
34
-
-
35748966123
-
Quantitative methylation analysis of resection margins and lymph nodes in oral squamous cell carcinoma
-
Shaw R, Hall G, Woolgar J et al (2007). Quantitative methylation analysis of resection margins and lymph nodes in oral squamous cell carcinoma. Br J Oral Maxillofac Surg 45: 617-622.
-
(2007)
Br J Oral Maxillofac Surg
, vol.45
, pp. 617-622
-
-
Shaw, R.1
Hall, G.2
Woolgar, J.3
-
35
-
-
77957376763
-
p16(INK4A) promoter hypermethylation is associated with invasiveness and prognosis of oral squamous cell carcinoma in an age-dependent manner
-
Su P, Huang W, Wu H, Wu C, Liu T, Kao S (2010). p16(INK4A) promoter hypermethylation is associated with invasiveness and prognosis of oral squamous cell carcinoma in an age-dependent manner. Oral Oncol 46: 734-739.
-
(2010)
Oral Oncol
, vol.46
, pp. 734-739
-
-
Su, P.1
Huang, W.2
Wu, H.3
Wu, C.4
Liu, T.5
Kao, S.6
-
36
-
-
70349175538
-
Molecular pathology of RUNX3 in human carcinogenesis
-
Subramaniam M, Chan J, Yeoh K et al (2009). Molecular pathology of RUNX3 in human carcinogenesis. Biochim Biophys Acta 1796: 315-331.
-
(2009)
Biochim Biophys Acta
, vol.1796
, pp. 315-331
-
-
Subramaniam, M.1
Chan, J.2
Yeoh, K.3
-
37
-
-
70449592332
-
Gene hypermethylation in tumor tissue of advanced oral squamous cell carcinoma patients
-
Supic G, Kozomara R, Brankovic-Magic M, Jovic N, Magic Z (2009). Gene hypermethylation in tumor tissue of advanced oral squamous cell carcinoma patients. Oral Oncol 45: 1051-1057.
-
(2009)
Oral Oncol
, vol.45
, pp. 1051-1057
-
-
Supic, G.1
Kozomara, R.2
Brankovic-Magic, M.3
Jovic, N.4
Magic, Z.5
-
38
-
-
78650979029
-
Interaction between the MTHFR C677T polymorphism and alcohol - impact on oral cancer risk and multiple DNA methylation of tumor-related genes
-
Supic G, Jovic N, Kozomara R, Zeljic K, Magic Z (2011). Interaction between the MTHFR C677T polymorphism and alcohol - impact on oral cancer risk and multiple DNA methylation of tumor-related genes. J Dent Res 90: 65-70.
-
(2011)
J Dent Res
, vol.90
, pp. 65-70
-
-
Supic, G.1
Jovic, N.2
Kozomara, R.3
Zeljic, K.4
Magic, Z.5
-
39
-
-
33846013934
-
Analyses of promoter hypermethylation for RUNX3 and other tumor suppressor genes in nasopharyngeal carcinoma
-
Tan SH, Ida H, Goh BC, Hsieh W, Loh M, Ito Y (2006). Analyses of promoter hypermethylation for RUNX3 and other tumor suppressor genes in nasopharyngeal carcinoma. Anticancer Res 26: 4287-4292.
-
(2006)
Anticancer Res
, vol.26
, pp. 4287-4292
-
-
Tan, S.H.1
Ida, H.2
Goh, B.C.3
Hsieh, W.4
Loh, M.5
Ito, Y.6
-
40
-
-
33846481932
-
Runt-related transcription factor 3 expression in human oral squamous cell carcinomas; implication for tumor progression and prognosis
-
Tanji Y, Osaki M, Nagahama Y, Kodani I, Ryoke K, Ito H (2007). Runt-related transcription factor 3 expression in human oral squamous cell carcinomas; implication for tumor progression and prognosis. Oral Oncol 43: 88-94.
-
(2007)
Oral Oncol
, vol.43
, pp. 88-94
-
-
Tanji, Y.1
Osaki, M.2
Nagahama, Y.3
Kodani, I.4
Ryoke, K.5
Ito, H.6
-
41
-
-
3843072194
-
RUNX3 inhibits cell proliferation and induces apoptosis by reinstating transforming growth factor beta responsiveness in esophageal adenocarcinoma cells
-
Torquati A, O'rear L, Longobardi L, Spagnoli A, Richards W, Daniel B (2004). RUNX3 inhibits cell proliferation and induces apoptosis by reinstating transforming growth factor beta responsiveness in esophageal adenocarcinoma cells. Surgery 136: 310-316.
-
(2004)
Surgery
, vol.136
, pp. 310-316
-
-
Torquati, A.1
O'rear, L.2
Longobardi, L.3
Spagnoli, A.4
Richards, W.5
Daniel, B.6
-
42
-
-
67651240362
-
RUNX3 has an oncogenic role in head and neck cancer
-
Tsunematsu T, Kudo Y, Iizuka S et al (2009). RUNX3 has an oncogenic role in head and neck cancer. PLoS ONE 4: 1-12.
-
(2009)
PLoS ONE
, vol.4
, pp. 1-12
-
-
Tsunematsu, T.1
Kudo, Y.2
Iizuka, S.3
-
43
-
-
31544468969
-
Epigenetic inactivation of Wnt inhibitory factor-1 plays an important role in bladder cancer through aberrant canonical Wnt/beta-catenin signaling pathway
-
Urakami S, Shiina H, Enokida H et al (2006). Epigenetic inactivation of Wnt inhibitory factor-1 plays an important role in bladder cancer through aberrant canonical Wnt/beta-catenin signaling pathway. Clin Cancer Res 12: 383-391.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 383-391
-
-
Urakami, S.1
Shiina, H.2
Enokida, H.3
-
44
-
-
0033866818
-
Molecular pathogenesis of oral squamous carcinoma
-
Williams HK (2000). Molecular pathogenesis of oral squamous carcinoma. Mol Pathol 53: 165-172.
-
(2000)
Mol Pathol
, vol.53
, pp. 165-172
-
-
Williams, H.K.1
-
45
-
-
0141995804
-
WIF1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer
-
Wissmann C, Wild PJ, Kaiser S et al (2003). WIF1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer. J Pathol 201: 204-212.
-
(2003)
J Pathol
, vol.201
, pp. 204-212
-
-
Wissmann, C.1
Wild, P.J.2
Kaiser, S.3
-
46
-
-
34548513807
-
Promoter hypermethylation of RASSF1A and RUNX3 genes as an independent prognostic prediction marker in surgically resected non-small cell lung cancers
-
Yanagawa N, Tamura G, Oizumi H et al (2007). Promoter hypermethylation of RASSF1A and RUNX3 genes as an independent prognostic prediction marker in surgically resected non-small cell lung cancers. Lung Cancer 58: 131.
-
(2007)
Lung Cancer
, vol.58
, pp. 131
-
-
Yanagawa, N.1
Tamura, G.2
Oizumi, H.3
-
47
-
-
30944433183
-
Wnt/beta-catenin signaling inhibits death receptor-mediated apoptosis and promotes invasive growth of HNSCC
-
Yang F, Zeng Q, Yu G, Li S, Wang C (2006). Wnt/beta-catenin signaling inhibits death receptor-mediated apoptosis and promotes invasive growth of HNSCC. Cell Signal 18: 679-687.
-
(2006)
Cell Signal
, vol.18
, pp. 679-687
-
-
Yang, F.1
Zeng, Q.2
Yu, G.3
Li, S.4
Wang, C.5
|