SiRNA-mediated knockdown of aryl hydrocarbon receptor nuclear translocator 2 affects hypoxia-inducible factor-1 regulatory signaling and metabolism in human breast cancer cells

FEBS Letters

Volumn 585, Issue 20, 2011, Pages 3310-3315

  Qin, Xian Yang ^a,b   Wei, Feifei ^c   Yoshinaga, Jun ^b   Yonemoto, Junzo ^a   Tanokura, Masaru ^c   Sone, Hideko ^a  

^a NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Aryl hydrocarbon receptor nuclear translocator 2; Breast cancer; Hypoxia inducible factor 1; Metabolomics; Nuclear magnetic resonance

Indexed keywords

ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR 2; BETAINE; GLUCOSE; GLYCINE; HYPOXIA INDUCIBLE FACTOR 1; INTERSTITIAL COLLAGENASE; LACTIC ACID; MESSENGER RNA; PHOSPHORYLCHOLINE; PYRUVIC ACID; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VON HIPPEL LINDAU PROTEIN;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; GLYCOLYSIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; NEOPLASM PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 80054072674     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.09.017     Document Type: Article

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