Diazepam Blocks Striatal Lipid Peroxidation and Improves Stereotyped Activity in a Rat Model of Acute Stress

Basic and Clinical Pharmacology and Toxicology

Volumn 109, Issue 5, 2011, Pages 350-356

  Méndez Cuesta, Luis A ^a   Márquez Valadez, Berenice ^a   Pérez De La Cruz, Verónica ^a   Escobar Briones, Carolina ^b   Galván Arzate, Sonia ^a   Alvarez Ruiz, Yarummy ^a   Maldonado, Perla D ^a   Santana, Ricardo A ^a   Santamaría, Abel ^a   Carrillo Mora, Paul ^a  

^a NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTERONE; DIAZEPAM; SUPEROXIDE DISMUTASE;

ACUTE STRESS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; CORPUS STRIATUM; CORTICOSTERONE BLOOD LEVEL; ENZYME ACTIVITY; IMMOBILIZATION STRESS; LIPID PEROXIDATION; LOCOMOTION; MALE; MITOCHONDRION; MOTOR ACTIVITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; STEREOTYPY;

ANIMALS; ANTI-ANXIETY AGENTS; ANTIOXIDANTS; BLOTTING, WESTERN; CORTICOSTERONE; DIAZEPAM; IMMOBILIZATION; LIPID PEROXIDATION; MALE; MITOCHONDRIA; MOTOR ACTIVITY; NEOSTRIATUM; OXIDATIVE STRESS; RATS; RATS, WISTAR; STRESS, PHYSIOLOGICAL; SUPEROXIDE DISMUTASE;

ANIMALIA; RATTUS;

EID: 80054071523     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2011.00738.x     Document Type: Article

References (54)

1. Selye H. A syndrome produced by diverse nocuous agents. Nature 1936;138:32.
2. Esch T, Stefano GB, Fricchione GL, Benson H. The role of stress in neurodegenerative diseases and mental disorders. Neuro Endocrinol Lett 2002;23:199-208.
3. Swaab DF, Bao AM, Lucassen PJ. The stress system in the human brain in depression and neurodegeneration. Ageing Res Rev 2005;4:141-94.
4. Bao AM, Meynen G, Swaab DF. The stress system in depression and neurodegeneration: focus on the human hypothalamus. Brain Res Rev 2008;57:531-53.
5. Glavin GB, Paré WP, Sandbak T, Bakke H, Murison R. Restraint stress in biomedical research: an update. Neurosci Biobehav Rev 1994;18:223-49.
6. Liu J, Wang X, Mori A. Immobilization stress-induced antioxidant defense changes in rat plasma: effect of treatment with reduced glutathione. Int J Biochem 1994;26:511-7.
7. Liu J, Wang X, Shigenaga MK, Yeo HC, Mori A, Ames B. Immobilization stress causes oxidative damage to lipid, protein, and DNA in the brain of rats. FASEB J 1996;10:1532-8.
8. Şahin E, Gümüşlü S. Immobilization stress in rat tissues: alterations in protein oxidation, lipid peroxidation and antioxidant defenses system. Comp Biochem Physiol C Toxicol Pharmacol 2007;144:342-7.
9. McEwen BS. The neurobiology of stress: from serendipity to clinical relevance. Brain Res 2000;886:172-89.
10. Pardon MC. Stress and ageing interactions: a paradox in the context of shared etiological and physiopathological processes. Brain Res Rev 2007;54:251-73.
11. Lanfumey L, Mongeau R, Cohen-Salmon C, Hamon M. Corticosteroid-serotonin interactions in the neurobiological mechanisms of stress-related disorders. Neurosci Biobehav Rev 2008;32:1174-84.
12. Buynitsky T, Mostofsky DI. Restraint stress in biobehavioral research: recent developments. Neurosci Biobehav Rev 2009;33:1089-98.
13. Madrigal JLM, Moro MA, Lizasoain I, Lorenzo P, Fernández AP, Rodrigo J et al. Induction of cyclooxygenase-2 account of restraint stress-induced oxidative status in rat brain. Neuropsychopharmacol 2001;24:420-9.
14. Radak Z, Sasvari M, Nyakas C, Kaneko T, Tahara S, Ohno H et al. Single bout of exercise eliminates the immobilization-induced oxidative stress in rats. Neurochem Int 2001;39:33-8.
15. Zaidi SM, Banu N. Antioxidant potential of vitamins A, E and C in modulating oxidative stress in rat brain. Clin Chim Acta 2004;340:229-33.
16. Atif F, Yousuf S, Agarwal SK. Restraint stress-induced oxidative damage and its amelioration with selenium. Eur J Pharmacol 2008;600:59-63.
17. Bandelow B, Zohar J, Hollander E, Kasper S, Moller HJ. World Federation of Societies of Biological Psychiatry (WFSBP). Guidelines for the pharmacological treatment of anxiety, obsessive-compulsive and post-traumatic stress disorders. World J Biol Psychiatry 2001;3:171-99.
18. Schwartz RD, Huff RA, Yu X, Carter ML, Bishop M. Post-ischemic diazepam is neuroprotective in the gerbil hippocampus. Brain Res 1994;647:153-60.
19. Schwartz RD, Yu X, Katzman MR, Hayden-Hixson DM, Perry JM. Diazepam, given postischemia, protects selectively vulnerable neurons in the rat hippocampus and striatum. J Neurosci 1995;15:529-39.
20. Dowden J, Reid C, Dooley P, Corbett D. Diazepam-induced neuroprotection: dissociating the effects of hypothermia following global ischemia. Brain Res 1999;829:1-6.
21. Rajasekaran K. Seizure-induced oxidative stress in rat brain regions: blockade by nNOS inhibition. Pharmacol Biochem Behav 2005;80:263-72.
22. Musavi S, Kakkar P. Diazepam induced early oxidative changes at the subcellular level in rat brain. Mol Cell Biochem 1998;178:41-6.
23. Musavi S, Kakkar P. Effect of diazepam treatment and its withdrawal on pro/antioxidative processes in rat brain. Mol Cell Biochem 2003;245:51-6.
24. Musavi S, Kakkar P. Pro and antioxidant responses to repeated administration of diazepam in rat brain. Mol Cell Biochem 2000;206:97-103.
25. Carrillo-Mora P, Pérez De la Cruz V, Fortoul van Der Goes TI, Santamaría A. Protective effect of systemic L-kynurenine and probenecid administrations on behavioural and morphological alterations induced by toxic soluble amyloid beta (25-35) in rat hippocampus. Behav Brain Res 2010;210:240-50.
26. Santamaría A, Salvatierra-Sánchez R, Vázquez-Román B, Santiago-López D, Villeda-Hernández J, Galván-Arzate S et al. Protective effects of the antioxidant selenium on quinolinic acid-induced neurotoxicity in rats: in vivo and in vitro studies. J Neurochem 2003;86:479-88.
27. Silva-Adaya D, Pérez-De La Cruz V, Herrera-Mundo MN, Mendoza-Macedo K, Villeda-Hernandez J, Binienda Z et al. Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of L-carnitine. J Neurochem 2008;105:677-89.
28. Santamaría D, Espinoza-González V, Ríos C, Santamaría A. Nω-Nitro-L-arginine, a nitric synthase inhibitor, antagonizes quinolinic acid-induced neurotoxicity and oxidative stress in rat striatal slices. Neurochem Res 1999;24:843-9.
29. Pérez-De La Cruz V, González-Cortés C, Pedraza-Chaverrí J, Maldonado PD, Andrés-Martínez L, Santamaría A. Protective effect of S-allylcysteine on 3-nitropropionic acid-induced lipid peroxidation and mitochondrial dysfunction in rat brain synaptosomes. Brain Res Bull 2006;68:379-83.
30. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-7.
31. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983;65:55-63.
32. Berridge MV, Tan AS. Characterization of the cellular reduction of 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction. Arch Biochem Biophys 1993;303:474-82.
33. Pedraza-Chaverrí J, Maldonado PD, Medina-Campos ON, Olivares-Corichi IM, Granados-Silvestre MA, Hernández-Pando R et al. Garlic ameliorates gentamicin nephrotoxicity: relation to antioxidant enzymes. Free Radic Biol Med 2000;29:602-11.
34. Ferrante RJ, Schulz JB, Kowall NW, Beal MF. Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra. Brain Res 1997;753:157-62.
35. Filipović D, Pajović SB. Differential regulation of CuZnSOD expression in rat brain by acute and/or chronic stress. Cell Mol Neurobiol 2009;29:673-81.
36. Lowy MT, Wittenberg L, Yamamoto BK. Effect of acute stress on hippocampal glutamate levels and spectrin proteolysis in young and aged rats. Neurochem 1995;65:268-74.
37. Sayre LM, Perry G, Smith MA. Oxidative stress and neurotoxicity. Chem Res Toxicol 2008;21:172-88.
38. McEwen BS. Stress and the aging hippocampus. Front Neuroendocrinol 1999;20:49-70.
39. Psarra AG, Sekeris CE. Glucocorticoid receptors and other nuclear transcription factors in mitochondria and possible functions. Biochim Biophys Acta 2009;1787:431-6.
40. Galeffi F, Sinnar S, Schwatz-Bloom RD. Diazepam promotes ATP recovery and prevents cytochrome C release in hippocampal slices after in vitro ischemia. J Neurochem 2000;75:1242-9.
41. Kumar A, Goyal R. Possible involvement of GABAergic modulation in the protective effect of gabapentin against immobilization stress induced behavior alterations and oxidative damage in mice. Fundam Clin Pharmacol 2007;21:575-81.
42. Goyal R, Anil K. Protective effects of alprazolam in acute immobilization stress-induced certain behavioral and biochemical alterations in mice. Pharmacol Rep 2007;59:284-90.
43. Kumar A, Goyal R, Prakash A. Possible GABAergic mechanism in the protective effect of allopregnenolone against immobilization stress. Eur J Pharmacol 2009;602:343-7.
44. Matsumoto K, Yobimoto K, Huong NT, Abdel-Fattah M, Van Hien T, Watanabe H. Psychological stress-induced enhancement of brain lipid peroxidation via nitric oxide systems and its modulation by anxiolytic and anxiogenic drugs in mice. Brain Res 1999;839:74-84.
45. Singh A, Kumar A. Protective effect of alprazolam against sleep deprivation-induced behavior alterations and oxidative damage in mice. Neurosci Res 2008;60:372-9.
46. Casellas P, Galiegue S, Basile AS. Peripheral benzodiazepine receptors and mitochondrial function. Neurochem Int 2002;40:475-86.
47. Miyoshi M, Ito H, Arakawa R, Takahashi H, Takano H, Higuchi M et al. Quantitative analysis of peripheral benzodiazepine receptor in the human brain using PET with 11C-AC-5216. J Nucl Med 2009;50:1095-101.
48. Leducq N, Bono F, Sulpice T, Vin V, Janiak P, Le Fur G et al. Role of peripheral benzodiazepine receptors in mitochondrial, cellular, and cardiac damage induced by oxidative stress and ischemia-reperfusion. J Pharmacol Exp Ther 2003;306:828-37.
49. AR and hypothermic effects. Neurochem Int 2009;55:164-73.
50. Zaidi SM, Al-Qirim TM, Hoda N, Banu N. Modulation of restraint stress induced oxidative changes in rats by antioxidant vitamins. J Nutr Biochem 2003;14:633-6.
51. Katz RJ, Roth KA, Carrol BJ. Acute and chronic stress effects on open field activity in the rat: implications for a model of depression. Neurosci Biobehav Rev 1981;5:247-51.
52. 1A agonist on stress induced deficit in open field locomotor activity of rats: evidence that this model identifies anxiolytic-like activity. Neuropharmacol 1989;5:471-6.
53. Sclafani A, Rendel A. Effect of food deprivation on wheel running activity in normal, dietary obese and dietary lean rats. Behav Biol 1978;24:220-8.
54. Koubi HE, Robin JP, Dewasmes G, Le Maho Y, Frutoso J, Minaire Y. Fasting-induced rise in locomotor activity in rats coincides with increased protein utilization. Physiol Behav 1991;50:337-43.