Building on the foundation of daring hypotheses: Using the MKK4 metastasis suppressor to develop models of dormancy and metastatic colonization

FEBS Letters

Volumn 585, Issue 20, 2011, Pages 3159-3165

  Knopeke, Matthew T ^a,c   Ritschdorff, Eric T ^b   Clark, Robert ^a   Vander Griend, Donald J ^a   Khan, Shaheena ^a,d   Thobe, Megan ^a,e   Shear, Jason B ^b   Rinker Schaeffer, Carrie W ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c Science Department   (United States)

^d RUSH MEDICAL COLLEGE   (United States)

^e ELI LILLY AND COMPANY   (United States)

Author keywords

Dormancy models; Metastasis suppressor; Metastatic colonization; MKK4; Omentum; Ovarian cancer

Indexed keywords

CD82 ANTIGEN; METASTIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; NUCLEOSIDE DIPHOSPHATE KINASE NM23; PROTEIN P16; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; CANCER CELL; CANCER CELL CULTURE; CANCER GROWTH; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; DORMANCY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REPRESSION; HUMAN; IMMUNOCOMPETENT CELL; METASTASIS POTENTIAL; MINIMAL RESIDUAL DISEASE; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT;

ANTINEOPLASTIC AGENTS; DRUG DESIGN; MAP KINASE KINASE 4; MODELS, BIOLOGICAL; NEOPLASM PROTEINS; NEOPLASTIC CELLS, CIRCULATING;

EID: 80054068136     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.09.007     Document Type: Review

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