-
1
-
-
0038004740
-
Targeting JNK for therapeutic benefit: From junk to gold?
-
Manning, A.M. and Davis, R.J. (2003) Targeting JNK for therapeutic benefit: from junk to gold? Nat. Rev. Drug Discov. 2, 554-565
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 554-565
-
-
Manning, A.M.1
Davis, R.J.2
-
2
-
-
0035282334
-
Mammalian MAP kinase signalling cascades
-
Chang, L. and Karin, M. (2001) Mammalian MAP kinase signalling cascades. Nature 410, 37-40
-
(2001)
Nature
, vol.410
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
3
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis, R.J. (2000) Signal transduction by the JNK group of MAP kinases. Cell. 103, 239-252
-
(2000)
Cell.
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
5
-
-
0027184134
-
Novel members of the mitogen-activated protein kinase activator family in Xenopus laevis
-
Yashar, B.M., Kelley, C., Yee, K., Errede, B., and Zon, L.I. (1993) Novel members of the mitogen-activated protein kinase activator family in Xenopus laevis. Mol. Cell Biol. 13, 5738-5748
-
(1993)
Mol. Cell Biol.
, vol.13
, pp. 5738-5748
-
-
Yashar, B.M.1
Kelley, C.2
Yee, K.3
Errede, B.4
Zon, L.I.5
-
6
-
-
0028935974
-
Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms
-
Derijard, B., Raingeaud, J., Barrett, T., Wu, I.H., Han, J., Ulevitch, R.J., and Davis, R.J. (1995) Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms. Science 267, 682-685
-
(1995)
Science
, vol.267
, pp. 682-685
-
-
Derijard, B.1
Raingeaud, J.2
Barrett, T.3
Wu, I.H.4
Han, J.5
Ulevitch, R.J.6
Davis, R.J.7
-
7
-
-
0028558986
-
Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun
-
Sanchez, I., Hughes, R.T., Mayer, B.J., Yee, K., Woodgett, J.R., Avruch, J., Kyriakis, J.M., and Zon, L.I. (1994) Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature 372, 794-798
-
(1994)
Nature
, vol.372
, pp. 794-798
-
-
Sanchez, I.1
Hughes, R.T.2
Mayer, B.J.3
Yee, K.4
Woodgett, J.R.5
Avruch, J.6
Kyriakis, J.M.7
Zon, L.I.8
-
8
-
-
0028943245
-
Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2
-
Lin, A., Minden, A., Martinetto, H., Claret, F.X., Lange-Carter, C., Mercurio, F., Johnson, G.L., and Karin, M. (1995) Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2. Science 268, 286-290
-
(1995)
Science
, vol.268
, pp. 286-290
-
-
Lin, A.1
Minden, A.2
Martinetto, H.3
Claret, F.X.4
Lange-Carter, C.5
Mercurio, F.6
Johnson, G.L.7
Karin, M.8
-
9
-
-
0030786344
-
Mitogen-activated protein kinasekinase 7 is an activator of the c-Jun NH2-terminal kinase
-
Tournier, C., Whitmarsh, A.J., Cavanagh, J., Barrett, T., and Davis, R.J. (1997) Mitogen-activated protein kinasekinase 7 is an activator of the c-Jun NH2-terminal kinase. Proc. Natl Acad. Sci. USA 94, 7337-7342
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 7337-7342
-
-
Tournier, C.1
Whitmarsh, A.J.2
Cavanagh, J.3
Barrett, T.4
Davis, R.J.5
-
10
-
-
15144349962
-
Activation of stress-activated protein kinases/c-Jun N-terminal protein kinases (SAPKs/JNKs) by a novel mitogen-activated protein kinase kinase
-
Yao, Z., Diener, K., Wang, X.S., Zukowski, M., Matsumoto, G., Zhou, G., Mo, R., Sasaki, T., Nishina, H., Hui, C C., Tan, T.H., Woodgett, J.P., and Penninger, J.M. (1997) Activation of stress-activated protein kinases/c-Jun N-terminal protein kinases (SAPKs/JNKs) by a novel mitogen-activated protein kinase kinase. J. Biol. Chem. 272, 32378-32383
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32378-32383
-
-
Yao, Z.1
Diener, K.2
Wang, X.S.3
Zukowski, M.4
Matsumoto, G.5
Zhou, G.6
Mo, R.7
Sasaki, T.8
Nishina, H.9
Hui C, C.10
Tan, T.H.11
Woodgett, J.P.12
Penninger, J.M.13
-
11
-
-
0030702895
-
A novel SAPK/JNK kinase, MKK7, stimulated by TNFalpha and cellular stresses
-
Moriguchi, T., Toyoshima, F., Masuyama, N., Hanafusa, H., Gotoh, Y., and Nishida, E. (1997) A novel SAPK/JNK kinase, MKK7, stimulated by TNFalpha and cellular stresses. EMBO J. 16, 7045-7053
-
(1997)
EMBO J.
, vol.16
, pp. 7045-7053
-
-
Moriguchi, T.1
Toyoshima, F.2
Masuyama, N.3
Hanafusa, H.4
Gotoh, Y.5
Nishida, E.6
-
12
-
-
0032926898
-
The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases
-
Tournier, C., Whitmarsh, A.J., Cavanagh, J., Barrett, T., and Davis, R.J. (1999) The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases. Mol. Cell Biol. 19, 1569-1581
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 1569-1581
-
-
Tournier, C.1
Whitmarsh, A.J.2
Cavanagh, J.3
Barrett, T.4
Davis, R.J.5
-
13
-
-
0034668860
-
Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7
-
Fleming, Y., Armstrong, C.G., Morrice, N., Paterson, A., Goedert, M., and Cohen, P. (2000) Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7. Biochem. J. 352 (Pt 1), 145-154
-
(2000)
Biochem. J.
, vol.352
, Issue.PART 1
, pp. 145-154
-
-
Fleming, Y.1
Armstrong, C.G.2
Morrice, N.3
Paterson, A.4
Goedert, M.5
Cohen, P.6
-
14
-
-
0032585615
-
Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro
-
Lawler, S., Fleming, Y., Goedert, M., and Cohen, P. (1998) Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro. Curr. Biol. 8, 1387-1390
-
(1998)
Curr. Biol.
, vol.8
, pp. 1387-1390
-
-
Lawler, S.1
Fleming, Y.2
Goedert, M.3
Cohen, P.4
-
15
-
-
0034696630
-
Activation of JNK3 alpha 1 requires both MKK4 and MKK7: Kinetic characterization of in vitro phosphorylated JNK3 alpha 1
-
Lisnock, J., Griffin, P., Calaycay, J., Frantz, B., Parsons, J., O'Keefe, S.J., and LoGrasso, P. (2000) Activation of JNK3 alpha 1 requires both MKK4 and MKK7: kinetic characterization of in vitro phosphorylated JNK3 alpha 1. Biochemistry 39, 3141-3148
-
(2000)
Biochemistry
, vol.39
, pp. 3141-3148
-
-
Lisnock, J.1
Griffin, P.2
Calaycay, J.3
Frantz, B.4
Parsons, J.5
O'Keefe, S.J.6
LoGrasso, P.7
-
16
-
-
0035903222
-
Impaired synergistic activation of stress-activated protein kinase SAPK/JNK in mouse embryonic stem cells lacking SEK1/MKK4: Different contribution of SEK2/ MKK7 isoforms to the synergistic activation
-
Wada, T., Nakagawa, K., Watanabe, T., Nishitai, G., Seo, J., Kishimoto, H., Kitagawa, D., Sasaki, T., Penninger, J.M., Nishina, H., and Katada, T. (2001) Impaired synergistic activation of stress-activated protein kinase SAPK/JNK in mouse embryonic stem cells lacking SEK1/MKK4: different contribution of SEK2/ MKK7 isoforms to the synergistic activation. J. Biol. Chem. 276, 30892-30897
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30892-30897
-
-
Wada, T.1
Nakagawa, K.2
Watanabe, T.3
Nishitai, G.4
Seo, J.5
Kishimoto, H.6
Kitagawa, D.7
Sasaki, T.8
Penninger, J.M.9
Nishina, H.10
Katada, T.11
-
17
-
-
0037592952
-
Different properties of SEK1 and MKK7 in dual phosphorylation of stress-induced activated protein kinase SAPK/JNK in embryonic stem cells
-
Kishimoto, H., Nakagawa, K., Watanabe, T., Kitagawa, D., Momose, H., Seo, J., Nishitai, G., Shimizu, N., Ohata, S., Tanemura, S., Asaka, S., Goto, T., Fukushi, H., Yoshida, H., Suzuki, A., Sasaki, T., Wada, T., Penninger, J.M., Nishina, H., and Katada, T. (2003) Different properties of SEK1 and MKK7 in dual phosphorylation of stress-induced activated protein kinase SAPK/JNK in embryonic stem cells. J. Biol. Chem. 278, 16595-16601
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 16595-16601
-
-
Kishimoto, H.1
Nakagawa, K.2
Watanabe, T.3
Kitagawa, D.4
Momose, H.5
Seo, J.6
Nishitai, G.7
Shimizu, N.8
Ohata, S.9
Tanemura, S.10
Asaka, S.11
Goto, T.12
Fukushi, H.13
Yoshida, H.14
Suzuki, A.15
Sasaki, T.16
Wada, T.17
Penninger, J.M.18
Nishina, H.19
Katada, T.20
more..
-
18
-
-
4644362788
-
Physiological roles of SAPK/JNK signaling pathway
-
Nishina, H., Wada, T., and Katada, T. (2004) Physiological roles of SAPK/JNK signaling pathway. J. Biochem. 136, 123-126
-
(2004)
J. Biochem.
, vol.136
, pp. 123-126
-
-
Nishina, H.1
Wada, T.2
Katada, T.3
-
19
-
-
33744959530
-
Interacting JNK-docking sites in MKK7 promote binding and activation of JNK mitogen-activated protein kinases
-
Ho, D.T., Bardwell, A.J., Grewal, S., Iverson, C., and Bardwell, L. (2006) Interacting JNK-docking sites in MKK7 promote binding and activation of JNK mitogen-activated protein kinases. J. Biol. Chem. 281, 13169-13179
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 13169-13179
-
-
Ho, D.T.1
Bardwell, A.J.2
Grewal, S.3
Iverson, C.4
Bardwell, L.5
-
20
-
-
0042858567
-
A docking site in MKK4 mediates high affinity binding to JNK MAPKs and competes with similar docking sites in JNK substrates
-
Ho, D.T., Bardwell, A.J., Abdollahi, M., and Bardwell, L. (2003) A docking site in MKK4 mediates high affinity binding to JNK MAPKs and competes with similar docking sites in JNK substrates. J. Biol. Chem. 278, 32662-32672
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 32662-32672
-
-
Ho, D.T.1
Bardwell, A.J.2
Abdollahi, M.3
Bardwell, L.4
-
21
-
-
34248525404
-
Scaffold proteins of MAP-kinase modules
-
Dhanasekaran, D.N., Kashef, K., Lee, C.M., Xu, H., and Reddy, E.P. (2007) Scaffold proteins of MAP-kinase modules. Oncogene 26, 3185-3202
-
(2007)
Oncogene
, vol.26
, pp. 3185-3202
-
-
Dhanasekaran, D.N.1
Kashef, K.2
Lee, C.M.3
Xu, H.4
Reddy, E.P.5
-
22
-
-
0030826412
-
A cytoplasmic inhibitor of the JNK signal transduction pathway
-
DOI 10.1126/science.277.5326.693
-
Dickens, M., Rogers, J.S., Cavanagh, J., Raitano, A., Xia, Z., Halpern, J.R., Greenberg, M.E., Sawyers, C.L., and Davis, R.J. (1997) A cytoplasmic inhibitor of the JNK signal transduction pathway. Science 277, 693-696 (Pubitemid 27373916)
-
(1997)
Science
, vol.277
, Issue.5326
, pp. 693-696
-
-
Dickens, M.1
Rogers, J.S.2
Cavanagh, J.3
Raitano, A.4
Xia, Z.5
Halpern, J.R.6
Greenberg, M.E.7
Sawyers, C.L.8
Davis, R.J.9
-
23
-
-
0032825497
-
The JIP group of mitogen-activated protein kinase scaffold proteins
-
Yasuda, J., Whitmarsh, A.J., Cavanagh, J., Sharma, M., and Davis, R.J. (1999) The JIP group of mitogen-activated protein kinase scaffold proteins. Mol. Cell Biol. 19, 7245-7254
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 7245-7254
-
-
Yasuda, J.1
Whitmarsh, A.J.2
Cavanagh, J.3
Sharma, M.4
Davis, R.J.5
-
24
-
-
0033971177
-
Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3
-
Kelkar, N., Gupta, S., Dickens, M., and Davis, R.J. (2000) Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3. Mol. Cell Biol. 20, 1030-1043
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 1030-1043
-
-
Kelkar, N.1
Gupta, S.2
Dickens, M.3
Davis, R.J.4
-
25
-
-
0032694245
-
JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway
-
Ito, M., Yoshioka, K., Akechi, M., Yamashita, S., Takamatsu, N., Sugiyama, K., Hibi, M., Nakabeppu, Y., Shiba, T., and Yamamoto, K.I. (1999) JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway. Mol. Cell Biol. 19, 7539-7548
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 7539-7548
-
-
Ito, M.1
Yoshioka, K.2
Akechi, M.3
Yamashita, S.4
Takamatsu, N.5
Sugiyama, K.6
Hibi, M.7
Nakabeppu, Y.8
Shiba, T.9
Yamamoto, K.I.10
-
26
-
-
15044357454
-
Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways
-
Kelkar, N., Standen, C.L., and Davis, R.J. (2005) Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways. Mol. Cell Biol. 25, 2733-2743
-
(2005)
Mol. Cell Biol.
, vol.25
, pp. 2733-2743
-
-
Kelkar, N.1
Standen, C.L.2
Davis, R.J.3
-
27
-
-
0037195113
-
JLP: A scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors
-
Lee, C.M., Onesime, D., Reddy, C.D., Dhanasekaran, N., and Reddy, E.P. (2002) JLP: A scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors. Proc. Natl Acad. Sci. USA 99, 14189-14194
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 14189-14194
-
-
Lee, C.M.1
Onesime, D.2
Reddy, C.D.3
Dhanasekaran, N.4
Reddy, E.P.5
-
28
-
-
16344363064
-
Characterization of a novel human sperm-associated antigen 9 (SPAG9) having structural homology with c-Jun N-terminal kinase-interacting protein
-
Jagadish, N., Rana, R., Selvi, R., Mishra, D., Garg, M., Yadav, S., Herr, J.C., Okumura, K., Hasegawa, A., Koyama, K., and Suri, A. (2005) Characterization of a novel human sperm-associated antigen 9 (SPAG9) having structural homology with c-Jun N-terminal kinase-interacting protein. Biochem. J. 389, 73-82
-
(2005)
Biochem. J.
, vol.389
, pp. 73-82
-
-
Jagadish, N.1
Rana, R.2
Selvi, R.3
Mishra, D.4
Garg, M.5
Yadav, S.6
Herr, J.C.7
Okumura, K.8
Hasegawa, A.9
Koyama, K.10
Suri, A.11
-
29
-
-
0037439170
-
POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis
-
Xu, Z., Kukekov, N.V., and Greene, L.A. (2003) POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis. EMBO J. 22, 252261
-
(2003)
EMBO J.
, vol.22
, pp. 252-261
-
-
Xu, Z.1
Kukekov, N.V.2
Greene, L.A.3
-
30
-
-
0030614745
-
Actin-binding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-alpha activation of SAPK in melanoma cells
-
Marti, A., Luo, Z., Cunningham, C., Ohta, Y., Hartwig, J., Stossel, T.P., Kyriakis, J.M., and Avruch, J. (1997) Actin-binding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-alpha activation of SAPK in melanoma cells. J. Biol. Chem. 272, 2620-2628
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 2620-2628
-
-
Marti, A.1
Luo, Z.2
Cunningham, C.3
Ohta, Y.4
Hartwig, J.5
Stossel, T.P.6
Kyriakis, J.M.7
Avruch, J.8
-
31
-
-
77952777107
-
Filamin associates with stress signalling kinases MKK7 and MKK4 and regulates JNK activation
-
Nakagawa, K., Sugahara, M., Yamasaki, T., Kajiho, H., Takahashi, S., Hirayama, J., Minami, Y., Ohta, Y., Watanabe, T., Hata, Y., Katada, T., and Nishina, H. (2010) Filamin associates with stress signalling kinases MKK7 and MKK4 and regulates JNK activation. Biochem. J. 427, 237-245
-
(2010)
Biochem. J.
, vol.427
, pp. 237-245
-
-
Nakagawa, K.1
Sugahara, M.2
Yamasaki, T.3
Kajiho, H.4
Takahashi, S.5
Hirayama, J.6
Minami, Y.7
Ohta, Y.8
Watanabe, T.9
Hata, Y.10
Katada, T.11
Nishina, H.12
-
32
-
-
0033168580
-
A Caenorhabditis elegans JNK signal transduction pathway regulates coordinated movement via type-D GABAergic motor neurons
-
Kawasaki, M., Hisamoto, N., Iino, Y., Yamamoto, M., Ninomiya-Tsuji, J., and Matsumoto, K. (1999) A Caenorhabditis elegans JNK signal transduction pathway regulates coordinated movement via type-D GABAergic motor neurons. EMBO J. 18, 3604-3615
-
(1999)
EMBO J.
, vol.18
, pp. 3604-3615
-
-
Kawasaki, M.1
Hisamoto, N.2
Iino, Y.3
Yamamoto, M.4
Ninomiya-Tsuji, J.5
Matsumoto, K.6
-
33
-
-
0034596988
-
A Caenorhabditis elegans MAP kinase kinase, MEK-1, is involved in stress responses
-
Koga, M., Zwaal, R., Guan, K.L., Avery, L., and Ohshima, Y. (2000) A Caenorhabditis elegans MAP kinase kinase, MEK-1, is involved in stress responses. EMBO J. 19, 5148-5156
-
(2000)
EMBO J.
, vol.19
, pp. 5148-5156
-
-
Koga, M.1
Zwaal, R.2
Guan, K.L.3
Avery, L.4
Ohshima, Y.5
-
34
-
-
0035903537
-
Jkk-1 and mek-1 regulate body movement coordination and response to heavy metals through jnk-1 in Caenorhabditis elegans
-
Villanueva, A., Lozano, J., Morales, A., Lin, X., Deng, X., Hengartner, M.O., and Kolesnick, R.N. (2001) jkk-1 and mek-1 regulate body movement coordination and response to heavy metals through jnk-1 in Caenorhabditis elegans. EMBO J. 20, 5114-5128
-
(2001)
EMBO J.
, vol.20
, pp. 5114-5128
-
-
Villanueva, A.1
Lozano, J.2
Morales, A.3
Lin, X.4
Deng, X.5
Hengartner, M.O.6
Kolesnick, R.N.7
-
35
-
-
0028875388
-
Hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement
-
Glise, B., Bourbon, H., and Noselli, S. (1995) hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement. Cell 83, 451-461
-
(1995)
Cell
, vol.83
, pp. 451-461
-
-
Glise, B.1
Bourbon, H.2
Noselli, S.3
-
36
-
-
0029834756
-
The drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye
-
Riesgo-Escovar, J.R., Jenni, M., Fritz, A., and Hafen, E. (1996) The drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye. Genes Dev. 10, 2759-2768
-
(1996)
Genes Dev.
, vol.10
, pp. 2759-2768
-
-
Riesgo-Escovar, J.R.1
Jenni, M.2
Fritz, A.3
Hafen, E.4
-
37
-
-
0029824847
-
A JNK signal transduction pathway that mediatesmorphogenesis and an immune response in Drosophila
-
Sluss, H.K., Han, Z., Barrett, T., Goberdhan, D.C., Wilson, C., Davis, R.J., and Ip, Y.T. (1996) A JNK signal transduction pathway that mediatesmorphogenesis and an immune response in Drosophila. Genes Dev. 10, 2745-2758
-
(1996)
Genes Dev.
, vol.10
, pp. 2745-2758
-
-
Sluss, H.K.1
Han, Z.2
Barrett, T.3
Goberdhan, D.C.4
Wilson, C.5
Davis, R.J.6
Ip, Y.T.7
-
38
-
-
0030742943
-
Drosophila Jun relays the Jun amino-terminal kinase signal transduction pathway to the Decapentaplegic signal transduction pathway in regulating epithelial cell sheet movement
-
Hou, X.S., Goldstein, E.S., and Perrimon, N. (1997) Drosophila Jun relays the Jun amino-terminal kinase signal transduction pathway to the Decapentaplegic signal transduction pathway in regulating epithelial cell sheet movement. Genes Dev. 11, 1728-1737
-
(1997)
Genes Dev.
, vol.11
, pp. 1728-1737
-
-
Hou, X.S.1
Goldstein, E.S.2
Perrimon, N.3
-
39
-
-
0030857388
-
Jun in drosophila development: Redundant and nonredundant functions and regulation by two MAPK signal transduction pathways
-
Kockel, L., Zeitlinger, J., Staszewski, L.M., Mlodzik, M., and Bohmann, D. (1997) Jun in drosophila development: redundant and nonredundant functions and regulation by two MAPK signal transduction pathways. Genes Dev. 11, 1748-1758
-
(1997)
Genes Dev.
, vol.11
, pp. 1748-1758
-
-
Kockel, L.1
Zeitlinger, J.2
Staszewski, L.M.3
Mlodzik, M.4
Bohmann, D.5
-
40
-
-
0030797351
-
Drosophila Jun kinase regulates expression of decapentaplegic via the ETS-domain protein Aop and the AP-1 transcription factor DJun during dorsal closure
-
Riesgo-Escovar, J.R. and Hafen, E. (1997) Drosophila Jun kinase regulates expression of decapentaplegic via the ETS-domain protein Aop and the AP-1 transcription factor DJun during dorsal closure. Genes Dev. 11, 1717-1727
-
(1997)
Genes Dev.
, vol.11
, pp. 1717-1727
-
-
Riesgo-Escovar, J.R.1
Hafen, E.2
-
41
-
-
0030708573
-
Common and distinct roles of DFos and DJun during Drosophila development
-
Riesgo-Escovar, J.R. and Hafen, E. (1997) Common and distinct roles of DFos and DJun during Drosophila development. Science 278, 669-672
-
(1997)
Science
, vol.278
, pp. 669-672
-
-
Riesgo-Escovar, J.R.1
Hafen, E.2
-
42
-
-
0031434434
-
Defective dorsal closure and loss of epidermal decapentaplegic expression in Drosophila fos mutants
-
Zeitlinger, J., Kockel, L., Peverali, F.A., Jackson, D.B., Mlodzik, M., and Bohmann, D. (1997) Defective dorsal closure and loss of epidermal decapentaplegic expression in Drosophila fos mutants. EMBO J. 16, 7393-7401
-
(1997)
EMBO J.
, vol.16
, pp. 7393-7401
-
-
Zeitlinger, J.1
Kockel, L.2
Peverali, F.A.3
Jackson, D.B.4
Mlodzik, M.5
Bohmann, D.6
-
43
-
-
0035943070
-
Downregulation of Jun kinase signaling in the amnioserosa is essential for dorsal closure of the Drosophila embryo
-
Reed, B.H., Wilk, R., and Lipshitz, H.D. (2001) Downregulation of Jun kinase signaling in the amnioserosa is essential for dorsal closure of the Drosophila embryo. Curr. Biol. 11, 1098-1108
-
(2001)
Curr. Biol.
, vol.11
, pp. 1098-1108
-
-
Reed, B.H.1
Wilk, R.2
Lipshitz, H.D.3
-
44
-
-
0031866058
-
A conserved p38 mitogen-activated protein kinase pathway regulates Drosophila immunity gene expression
-
Han, Z.S., Enslen, H., Hu, X., Meng, X., Wu, I.H., Barrett, T., Davis, R.J., and Ip, Y.T. (1998) A conserved p38 mitogen-activated protein kinase pathway regulates Drosophila immunity gene expression. Mol. Cell Biol. 18, 3527-3539
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 3527-3539
-
-
Han, Z.S.1
Enslen, H.2
Hu, X.3
Meng, X.4
Wu, I.H.5
Barrett, T.6
Davis, R.J.7
Ip, Y.T.8
-
45
-
-
70449597294
-
A non-redundant role for Drosophila Mkk4 and hemipterous/Mkk7 in TAK1-mediated activation of JNK
-
Geuking, P., Narasimamurthy, R., Lemaitre, B., Basler, K., and Leulier, F. (2009) A non-redundant role for Drosophila Mkk4 and hemipterous/Mkk7 in TAK1-mediated activation of JNK. PLoS One 4, e7709
-
(2009)
PLoS One
, vol.4
-
-
Geuking, P.1
Narasimamurthy, R.2
Lemaitre, B.3
Basler, K.4
Leulier, F.5
-
46
-
-
0032499687
-
SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis
-
Ganiatsas, S., Kwee, L., Fujiwara, Y., Perkins, A., Ikeda, T., Labow, M.A., and Zon, L.I. (1998) SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis. Proc. Natl Acad. Sci. USA 95, 6881-6886
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 6881-6886
-
-
Ganiatsas, S.1
Kwee, L.2
Fujiwara, Y.3
Perkins, A.4
Ikeda, T.5
Labow, M.A.6
Zon, L.I.7
-
47
-
-
0031029214
-
Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3
-
Nishina, H., Fischer, K.D., Radvanyi, L., Shahinian, A., Hakem, R., Rubie, E.A., Bernstein, A., Mak, T.W., Woodgett, J.R., and Penninger, J.M. (1997) Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3. Nature 385, 350-353
-
(1997)
Nature
, vol.385
, pp. 350-353
-
-
Nishina, H.1
Fischer, K.D.2
Radvanyi, L.3
Shahinian, A.4
Hakem, R.5
Rubie, E.A.6
Bernstein, A.7
Mak, T.W.8
Woodgett, J.R.9
Penninger, J.M.10
-
48
-
-
0033063568
-
Defective liver formation and liver cell apoptosis in mice lacking the stress signaling kinase SEK1/MKK4
-
Nishina, H., Vaz, C., Billia, P., Nghiem, M., Sasaki, T., De la Pompa, J.L., Furlonger, K., Paige, C., Hui, C., Fischer, K.D., Kishimoto, H., Iwatsubo, T., Katada, T., Woodgett, J.R., and Penninger, J.M. (1999) Defective liver formation and liver cell apoptosis in mice lacking the stress signaling kinase SEK1/MKK4. Development 126, 505-516
-
(1999)
Development
, vol.126
, pp. 505-516
-
-
Nishina, H.1
Vaz, C.2
Billia, P.3
Nghiem, M.4
Sasaki, T.5
De La Pompa, J.L.6
Furlonger, K.7
Paige, C.8
Hui, C.9
Fischer, K.D.10
Kishimoto, H.11
Iwatsubo, T.12
Katada, T.13
Woodgett, J.R.14
Penninger, J.M.15
-
49
-
-
12144290513
-
MKK7 couples stress signalling to G2/M cell-cycle progression and cellular senescence
-
Wada, T., Joza, N., Cheng, H.Y., Sasaki, T., Kozieradzki, I., Bachmaier, K., Katada, T., Schreiber, M., Wagner, E.F., Nishina, H., and Penninger, J.M. (2004) MKK7 couples stress signalling to G2/M cell-cycle progression and cellular senescence. Nat. Cell Biol. 6, 215-226
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 215-226
-
-
Wada, T.1
Joza, N.2
Cheng, H.Y.3
Sasaki, T.4
Kozieradzki, I.5
Bachmaier, K.6
Katada, T.7
Schreiber, M.8
Wagner, E.F.9
Nishina, H.10
Penninger, J.M.11
-
50
-
-
0036402460
-
SEK1/MKK4-mediated SAPK/JNK signaling participates in embryonic hepatoblast proliferation via a pathway different from NF-kappaB-induced anti-apoptosis
-
Watanabe, T., Nakagawa, K., Ohata, S., Kitagawa, D., Nishitai, G., Seo, J., Tanemura, S., Shimizu, N., Kishimoto, H., Wada, T., Aoki, J., Arai, H., Iwatsubo, T., Mochita, M., Satake, M., Ito, Y., Matsuyama, T., Mak, T.W., Penninger, J.M., Nishina, H., and Katada, T. (2002) SEK1/MKK4-mediated SAPK/JNK signaling participates in embryonic hepatoblast proliferation via a pathway different from NF-kappaB-induced anti-apoptosis. Dev. Biol. 250, 332-347
-
(2002)
Dev. Biol.
, vol.250
, pp. 332-347
-
-
Watanabe, T.1
Nakagawa, K.2
Ohata, S.3
Kitagawa, D.4
Nishitai, G.5
Seo, J.6
Tanemura, S.7
Shimizu, N.8
Kishimoto, H.9
Wada, T.10
Aoki, J.11
Arai, H.12
Iwatsubo, T.13
Mochita, M.14
Satake, M.15
Ito, Y.16
Matsuyama, T.17
Mak, T.W.18
Penninger, J.M.19
Nishina, H.20
Katada, T.21
more..
-
51
-
-
0030908341
-
2-terminal kinase activation, and defects in AP-1 transcriptional activity
-
DOI 10.1073/pnas.94.7.3004
-
Yang, D., Tournier, C., Wysk, M., Lu, H.T., Xu, J., Davis, R.J., and Flavell, R.A. (1997) Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity. Proc. Natl Acad. Sci. USA 94, 3004-3009 (Pubitemid 27157254)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.7
, pp. 3004-3009
-
-
Yang, D.1
Tournier, C.2
Wysk, M.3
Lu, H.-T.4
Xu, J.5
Davis, R.J.6
Flavell, R.A.7
-
52
-
-
0033118607
-
The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development
-
Kuan, C.Y., Yang, D.D., Samanta Roy, D.R., Davis, R.J., Rakic, P., and Flavell, R.A. (1999) The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development. Neuron 22, 667-676
-
(1999)
Neuron
, vol.22
, pp. 667-676
-
-
Kuan, C.Y.1
Yang, D.D.2
Samanta Roy, D.R.3
Davis, R.J.4
Rakic, P.5
Flavell, R.A.6
-
53
-
-
0032724021
-
Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2
-
Sabapathy, K., Jochum, W., Hochedlinger, K., Chang, L., Karin, M., and Wagner, E. F. (1999) Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2. Mech. Dev. 89, 115-124
-
(1999)
Mech. Dev.
, vol.89
, pp. 115-124
-
-
Sabapathy, K.1
Jochum, W.2
Hochedlinger, K.3
Chang, L.4
Karin, M.5
Wagner, E.F.6
-
54
-
-
0036422194
-
Non-canonical Wnt signalling and regulation of gastrulation movements
-
Tada, M., Concha, M.L., and Heisenberg, C.P. (2002) Non-canonical Wnt signalling and regulation of gastrulation movements. Semin. Cell Dev. Biol. 13, 251-260
-
(2002)
Semin. Cell Dev. Biol.
, vol.13
, pp. 251-260
-
-
Tada, M.1
Concha, M.L.2
Heisenberg, C.P.3
-
55
-
-
0034729910
-
Mechanisms of convergence and extension by cell intercalation
-
Keller, R., Davidson, L., Edlund, A., Elul, T., Ezin, M., Shook, D., and Skoglund, P. (2000) Mechanisms of convergence and extension by cell intercalation. Phil. Trans. R. Soc. Lond. B Biol. Sci. 355, 897-922
-
(2000)
Phil. Trans. R. Soc. Lond. B Biol. Sci.
, vol.355
, pp. 897-922
-
-
Keller, R.1
Davidson, L.2
Edlund, A.3
Elul, T.4
Ezin, M.5
Shook, D.6
Skoglund, P.7
-
56
-
-
0037032828
-
Shaping the vertebrate body plan by polarized embryonic cell movements
-
Keller, R. (2002) Shaping the vertebrate body plan by polarized embryonic cell movements. Science 298, 1950-1954
-
(2002)
Science
, vol.298
, pp. 1950-1954
-
-
Keller, R.1
-
57
-
-
33745611527
-
Gastrulation in zebrafish -All just about adhesion?
-
Solnica-Krezel, L. (2006) Gastrulation in zebrafish - all just about adhesion? Curr. Opin. Genet. Dev. 16, 433-441
-
(2006)
Curr. Opin. Genet. Dev.
, vol.16
, pp. 433-441
-
-
Solnica-Krezel, L.1
-
58
-
-
0036166289
-
JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates
-
Yamanaka, H., Moriguchi, T., Masuyama, N., Kusakabe, M., Hanafusa, H., Takada, R., Takada, S., and Nishida, E. (2002) JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates. EMBO Rep. 3, 69-75
-
(2002)
EMBO Rep.
, vol.3
, pp. 69-75
-
-
Yamanaka, H.1
Moriguchi, T.2
Masuyama, N.3
Kusakabe, M.4
Hanafusa, H.5
Takada, R.6
Takada, S.7
Nishida, E.8
-
59
-
-
33846396811
-
Frizzled/PCP signalling: A conserved mechanism regulating cell polarity and directed motility
-
Seifert, J.R. and Mlodzik, M. (2007) Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility. Nat. Rev. Genet. 8, 126-138
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 126-138
-
-
Seifert, J.R.1
Mlodzik, M.2
-
60
-
-
77954129618
-
Negative regulation of wnt11 expression by Jnk signaling during zebrafish gastrulation
-
Seo, J., Asaoka, Y., Nagai, Y., Hirayama, J., Yamasaki, T., Namae, M., Ohata, S., Shimizu, N., Negishi, T., Kitagawa, D., Kondoh, H., Furutani-Seiki, M., Penninger, J.M., Katada, T., and Nishina, H. (2010) Negative regulation of wnt11 expression by Jnk signaling during zebrafish gastrulation. J. Cell Biochem. 110, 1022-1037
-
(2010)
J. Cell Biochem.
, vol.110
, pp. 1022-1037
-
-
Seo, J.1
Asaoka, Y.2
Nagai, Y.3
Hirayama, J.4
Yamasaki, T.5
Namae, M.6
Ohata, S.7
Shimizu, N.8
Negishi, T.9
Kitagawa, D.10
Kondoh, H.11
Furutani-Seiki, M.12
Penninger, J.M.13
Katada, T.14
Nishina, H.15
-
61
-
-
34547436998
-
A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida
-
Rui, Y., Xu, Z., Xiong, B., Cao, Y., Lin, S., Zhang, M., Chan, S.C., Luo, W., Han, Y., Lu, Z., Ye, Z., Zhou, H.M., Han, J., Meng, A., and Lin, S.C. (2007) A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida. Dev. Cell 13, 268-282
-
(2007)
Dev. Cell
, vol.13
, pp. 268-282
-
-
Rui, Y.1
Xu, Z.2
Xiong, B.3
Cao, Y.4
Lin, S.5
Zhang, M.6
Chan, S.C.7
Luo, W.8
Han, Y.9
Lu, Z.10
Ye, Z.11
Zhou, H.M.12
Han, J.13
Meng, A.14
Lin, S.C.15
-
62
-
-
36048978128
-
Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death
-
Wang, X., Nadarajah, B., Robinson, A.C., McColl, B.W., Jin, J.W., Dajas-Bailador, F., Boot-Handford, R.P., and Tournier, C. (2007) Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death. Mol. Cell Biol. 27, 7935-7946
-
(2007)
Mol. Cell Biol.
, vol.27
, pp. 7935-7946
-
-
Wang, X.1
Nadarajah, B.2
Robinson, A.C.3
McColl, B.W.4
Jin, J.W.5
Dajas-Bailador, F.6
Boot-Handford, R.P.7
Tournier, C.8
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