메뉴 건너뛰기




Volumn 25, Issue 4, 2011, Pages 173-179

Efficient peripheral construction of functional human regulatory CD4 +CD25 highFoxp3 + T cells in NOD/SCID mice grafted with fetal human thymus/liver tissues and CD34 + cells

Author keywords

Foxp3; Humanized mice; Regulatory T cells; Transplant tolerance

Indexed keywords

CD24 ANTIGEN; CD34 ANTIGEN; CD45RO ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 7 RECEPTOR; TRANSCRIPTION FACTOR FOXP3;

EID: 80054067718     PISSN: 09663274     EISSN: 18785492     Source Type: Journal    
DOI: 10.1016/j.trim.2011.08.003     Document Type: Article
Times cited : (5)

References (45)
  • 1
    • 0034716925 scopus 로고    scopus 로고
    • Cells: key controllers of immunologic self-tolerance
    • Sakaguchi S., Regulatory T. Cells: key controllers of immunologic self-tolerance. Cell 2000, 101(5):455-458.
    • (2000) Cell , vol.101 , Issue.5 , pp. 455-458
    • Sakaguchi, S.1    Regulatory, T.2
  • 2
    • 0035806244 scopus 로고    scopus 로고
    • Ex vivo isolation and characterization of CD4+CD25+T cells with regulatory properties from human blood
    • Dieckmann D., Plottner H., Berchtold S., Berger T., Schuler G. Ex vivo isolation and characterization of CD4+CD25+T cells with regulatory properties from human blood. J Exp Med 2001, 193(11):1303-1310.
    • (2001) J Exp Med , vol.193 , Issue.11 , pp. 1303-1310
    • Dieckmann, D.1    Plottner, H.2    Berchtold, S.3    Berger, T.4    Schuler, G.5
  • 3
    • 0035806290 scopus 로고    scopus 로고
    • Identification and functional characterization of human CD4+CD25+T cells with regulatory properties isolated from peripheral blood
    • Jonuleit H., Schmitt E., Stassen M., Tuettenberg A., Knop J., Enk A.H. Identification and functional characterization of human CD4+CD25+T cells with regulatory properties isolated from peripheral blood. J Exp Med 2001, 193(11):1285-1294.
    • (2001) J Exp Med , vol.193 , Issue.11 , pp. 1285-1294
    • Jonuleit, H.1    Schmitt, E.2    Stassen, M.3    Tuettenberg, A.4    Knop, J.5    Enk, A.H.6
  • 4
    • 0035525739 scopus 로고    scopus 로고
    • Human CD4+CD25+ cells: a naturally occurring population of regulatory T cells
    • Ng W.F., Duggan P.J., Ponchel F., Matarese G., Lombardi G., Edwards A.D., et al. Human CD4+CD25+ cells: a naturally occurring population of regulatory T cells. Blood 2001, 98(9):2736-2744.
    • (2001) Blood , vol.98 , Issue.9 , pp. 2736-2744
    • Ng, W.F.1    Duggan, P.J.2    Ponchel, F.3    Matarese, G.4    Lombardi, G.5    Edwards, A.D.6
  • 5
    • 0035413350 scopus 로고    scopus 로고
    • CD4+CD25high regulatory cells in human peripheral blood
    • Baecher-Allan C., Brown J.A., Freeman G.J., Hafler D.A. CD4+CD25high regulatory cells in human peripheral blood. J Immunol 2001, 167(3):1245-1253.
    • (2001) J Immunol , vol.167 , Issue.3 , pp. 1245-1253
    • Baecher-Allan, C.1    Brown, J.A.2    Freeman, G.J.3    Hafler, D.A.4
  • 6
    • 34247643786 scopus 로고    scopus 로고
    • The regulation of Foxp3 expression in regulatory CD4+CD25+T cells: multiple pathways on the road
    • Zhang L., Zhao Y. The regulation of Foxp3 expression in regulatory CD4+CD25+T cells: multiple pathways on the road. J Cell Physiol 2007, 211(3):590-597.
    • (2007) J Cell Physiol , vol.211 , Issue.3 , pp. 590-597
    • Zhang, L.1    Zhao, Y.2
  • 7
    • 0035320679 scopus 로고    scopus 로고
    • Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
    • Jordan M.S., Boesteanu A., Reed A.J., Petrone A.L., Holenbeck A.E., Lerman M.A., et al. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunol 2001, 2(4):301-306.
    • (2001) Nat Immunol , vol.2 , Issue.4 , pp. 301-306
    • Jordan, M.S.1    Boesteanu, A.2    Reed, A.J.3    Petrone, A.L.4    Holenbeck, A.E.5    Lerman, M.A.6
  • 8
    • 0035869432 scopus 로고    scopus 로고
    • IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo
    • Hara M., Kingsley C.I., Niimi M., Read S., Turvey S.E., Bushell A.R., et al. IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo. J Immunol 2001, 166(6):3789-3796.
    • (2001) J Immunol , vol.166 , Issue.6 , pp. 3789-3796
    • Hara, M.1    Kingsley, C.I.2    Niimi, M.3    Read, S.4    Turvey, S.E.5    Bushell, A.R.6
  • 9
    • 0035399985 scopus 로고    scopus 로고
    • Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen
    • Thorstenson K.M., Khoruts A. Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen. J Immunol 2001, 167(1):188-195.
    • (2001) J Immunol , vol.167 , Issue.1 , pp. 188-195
    • Thorstenson, K.M.1    Khoruts, A.2
  • 10
    • 33646575622 scopus 로고    scopus 로고
    • In vivo peripheral expansion of naive CD4+CD25high FoxP3+ regulatory T cells in patients with multiple myeloma
    • Beyer M., Kochanek M., Giese T., Endl E., Weihrauch M.R., Knolle P.A., et al. In vivo peripheral expansion of naive CD4+CD25high FoxP3+ regulatory T cells in patients with multiple myeloma. Blood 2006, 107(10):3940-3949.
    • (2006) Blood , vol.107 , Issue.10 , pp. 3940-3949
    • Beyer, M.1    Kochanek, M.2    Giese, T.3    Endl, E.4    Weihrauch, M.R.5    Knolle, P.A.6
  • 11
    • 46749103362 scopus 로고    scopus 로고
    • Autologous bone marrow transplantation in autoimmune arthritis restores immune homeostasis through CD4+CD25+FOXP3+ regulatory T cells
    • Roord S.T., de Jager W., Boon L., Wulffraat N., Martens A., Prakken B., et al. Autologous bone marrow transplantation in autoimmune arthritis restores immune homeostasis through CD4+CD25+FOXP3+ regulatory T cells. Blood 2008.
    • (2008) Blood
    • Roord, S.T.1    de Jager, W.2    Boon, L.3    Wulffraat, N.4    Martens, A.5    Prakken, B.6
  • 12
    • 34548848237 scopus 로고    scopus 로고
    • Deficient CD4+CD25+FOXP3+ T regulatory cells in acquired aplastic anemia
    • Solomou E.E., Rezvani K., Mielke S., Malide D., Keyvanfar K., Visconte V., et al. Deficient CD4+CD25+FOXP3+ T regulatory cells in acquired aplastic anemia. Blood 2007, 110(5):1603-1606.
    • (2007) Blood , vol.110 , Issue.5 , pp. 1603-1606
    • Solomou, E.E.1    Rezvani, K.2    Mielke, S.3    Malide, D.4    Keyvanfar, K.5    Visconte, V.6
  • 13
    • 40949164727 scopus 로고    scopus 로고
    • CTLA-4 and CD4+CD25+ regulatory T cells inhibit protective immunity to filarial parasites in vivo
    • Taylor M.D., Harris A., Babayan S.A., Bain O., Culshaw A., Allen J.E., et al. CTLA-4 and CD4+CD25+ regulatory T cells inhibit protective immunity to filarial parasites in vivo. J Immunol 2007, 179(7):4626-4634.
    • (2007) J Immunol , vol.179 , Issue.7 , pp. 4626-4634
    • Taylor, M.D.1    Harris, A.2    Babayan, S.A.3    Bain, O.4    Culshaw, A.5    Allen, J.E.6
  • 14
    • 27144500976 scopus 로고    scopus 로고
    • Reduced frequency of FOXP3+CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host disease
    • Zorn E., Kim H.T., Lee S.J., Floyd B.H., Litsa D., Arumugarajah S., et al. Reduced frequency of FOXP3+CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host disease. Blood 2005, 106(8):2903-2911.
    • (2005) Blood , vol.106 , Issue.8 , pp. 2903-2911
    • Zorn, E.1    Kim, H.T.2    Lee, S.J.3    Floyd, B.H.4    Litsa, D.5    Arumugarajah, S.6
  • 15
    • 33745778016 scopus 로고    scopus 로고
    • CD4+25+ regulatory T cells limit Th1-autoimmunity by inducing IL-10 producing T cells following human lung transplantation
    • Bharat A., Fields R.C., Steward N., Trulock E.P., Patterson G.A., Mohanakumar T. CD4+25+ regulatory T cells limit Th1-autoimmunity by inducing IL-10 producing T cells following human lung transplantation. Am J Transplant 2006, 6(8):1799-1808.
    • (2006) Am J Transplant , vol.6 , Issue.8 , pp. 1799-1808
    • Bharat, A.1    Fields, R.C.2    Steward, N.3    Trulock, E.P.4    Patterson, G.A.5    Mohanakumar, T.6
  • 16
    • 34248146578 scopus 로고    scopus 로고
    • Allosuppressive donor CD4+CD25+ regulatory T cells detach from the graft and circulate in recipients after liver transplantation
    • Demirkiran A., Bosma B.M., Kok A., Baan C.C., Metselaar H.J., Ijzermans J.N., et al. Allosuppressive donor CD4+CD25+ regulatory T cells detach from the graft and circulate in recipients after liver transplantation. J Immunol 2007, 178(10):6066-6072.
    • (2007) J Immunol , vol.178 , Issue.10 , pp. 6066-6072
    • Demirkiran, A.1    Bosma, B.M.2    Kok, A.3    Baan, C.C.4    Metselaar, H.J.5    Ijzermans, J.N.6
  • 17
    • 23044463715 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells control the induction of antigen-specific CD4+ helper T cell responses in cancer patients
    • Nishikawa H., Jager E., Ritter G., Old L.J., Gnjatic S. CD4+CD25+ regulatory T cells control the induction of antigen-specific CD4+ helper T cell responses in cancer patients. Blood 2005, 106(3):1008-1011.
    • (2005) Blood , vol.106 , Issue.3 , pp. 1008-1011
    • Nishikawa, H.1    Jager, E.2    Ritter, G.3    Old, L.J.4    Gnjatic, S.5
  • 18
    • 30744442099 scopus 로고    scopus 로고
    • Effect of CD4+CD25+ and CD4+CD25- T regulatory cells on the generation of cytolytic T cell response to a self but human tumor-associated epitope in vitro
    • Chattopadhyay S., Mehrotra S., Chhabra A., Hegde U., Mukherji B., Chakraborty N.G. Effect of CD4+CD25+ and CD4+CD25- T regulatory cells on the generation of cytolytic T cell response to a self but human tumor-associated epitope in vitro. J Immunol 2006, 176(2):984-990.
    • (2006) J Immunol , vol.176 , Issue.2 , pp. 984-990
    • Chattopadhyay, S.1    Mehrotra, S.2    Chhabra, A.3    Hegde, U.4    Mukherji, B.5    Chakraborty, N.G.6
  • 19
    • 33745959565 scopus 로고    scopus 로고
    • Reconstitution of a functional human immune system in immunodeficient mice through combined human fetal thymus/liver and CD34+ cell transplantation
    • Lan P., Tonomura N., Shimizu A., Wang S., Yang Y.G. Reconstitution of a functional human immune system in immunodeficient mice through combined human fetal thymus/liver and CD34+ cell transplantation. Blood 2006, 108(2):487-492.
    • (2006) Blood , vol.108 , Issue.2 , pp. 487-492
    • Lan, P.1    Tonomura, N.2    Shimizu, A.3    Wang, S.4    Yang, Y.G.5
  • 20
    • 33846104485 scopus 로고    scopus 로고
    • Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses
    • Watanabe S., Terashima K., Ohta S., Horibata S., Yajima M., Shiozawa Y., et al. Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses. Blood 2007, 109(1):212-218.
    • (2007) Blood , vol.109 , Issue.1 , pp. 212-218
    • Watanabe, S.1    Terashima, K.2    Ohta, S.3    Horibata, S.4    Yajima, M.5    Shiozawa, Y.6
  • 21
    • 0042243661 scopus 로고    scopus 로고
    • Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/gammacnull mice model
    • Hiramatsu H., Nishikomori R., Heike T., Ito M., Kobayashi K., Katamura K., et al. Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/gammacnull mice model. Blood 2003, 102(3):873-880.
    • (2003) Blood , vol.102 , Issue.3 , pp. 873-880
    • Hiramatsu, H.1    Nishikomori, R.2    Heike, T.3    Ito, M.4    Kobayashi, K.5    Katamura, K.6
  • 22
    • 0042235806 scopus 로고    scopus 로고
    • Functional CD5+ B cells develop predominantly in the spleen of NOD/SCID/gammac(null) (NOG) mice transplanted either with human umbilical cord blood, bone marrow, or mobilized peripheral blood CD34+ cells
    • Matsumura T., Kametani Y., Ando K., Hirano Y., Katano I., Ito R., et al. Functional CD5+ B cells develop predominantly in the spleen of NOD/SCID/gammac(null) (NOG) mice transplanted either with human umbilical cord blood, bone marrow, or mobilized peripheral blood CD34+ cells. Exp Hematol 2003, 31(9):789-797.
    • (2003) Exp Hematol , vol.31 , Issue.9 , pp. 789-797
    • Matsumura, T.1    Kametani, Y.2    Ando, K.3    Hirano, Y.4    Katano, I.5    Ito, R.6
  • 24
    • 33750705617 scopus 로고    scopus 로고
    • Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1
    • Melkus M.W., Estes J.D., Padgett-Thomas A., Gatlin J., Denton P.W., Othieno F.A., et al. Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1. Nat Med 2006, 12(11):1316-1322.
    • (2006) Nat Med , vol.12 , Issue.11 , pp. 1316-1322
    • Melkus, M.W.1    Estes, J.D.2    Padgett-Thomas, A.3    Gatlin, J.4    Denton, P.W.5    Othieno, F.A.6
  • 25
    • 23744474685 scopus 로고    scopus 로고
    • Development of functional human blood and immune systems in NOD/SCID/IL2 receptor gamma chain(null) mice
    • Ishikawa F., Yasukawa M., Lyons B., Yoshida S., Miyamoto T., Yoshimoto G., et al. Development of functional human blood and immune systems in NOD/SCID/IL2 receptor gamma chain(null) mice. Blood 2005, 106(5):1565-1573.
    • (2005) Blood , vol.106 , Issue.5 , pp. 1565-1573
    • Ishikawa, F.1    Yasukawa, M.2    Lyons, B.3    Yoshida, S.4    Miyamoto, T.5    Yoshimoto, G.6
  • 26
    • 0028092365 scopus 로고
    • Autoimmunity versus allo- and xeno-reactivity in SCID mice
    • Elkon K.B., Ashany D. Autoimmunity versus allo- and xeno-reactivity in SCID mice. Int Rev Immunol 1994, 11(4):283-293.
    • (1994) Int Rev Immunol , vol.11 , Issue.4 , pp. 283-293
    • Elkon, K.B.1    Ashany, D.2
  • 27
    • 0038523806 scopus 로고    scopus 로고
    • Identification of a novel coronavirus in patients with severe acute respiratory syndrome
    • Drosten C., Gunther S., Preiser W., van der Werf S., Brodt H.R., Becker S., et al. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med 2003, 348(20):1967-1976.
    • (2003) N Engl J Med , vol.348 , Issue.20 , pp. 1967-1976
    • Drosten, C.1    Gunther, S.2    Preiser, W.3    van der Werf, S.4    Brodt, H.R.5    Becker, S.6
  • 28
    • 85047691376 scopus 로고    scopus 로고
    • Mouse retrovirus mediates porcine endogenous retrovirus transmission into human cells in long-term human-porcine chimeric mice
    • Yang Y.G., Wood J.C., Lan P., Wilkinson R.A., Sykes M., Fishman J.A., et al. Mouse retrovirus mediates porcine endogenous retrovirus transmission into human cells in long-term human-porcine chimeric mice. J Clin Invest 2004, 114(5):695-700.
    • (2004) J Clin Invest , vol.114 , Issue.5 , pp. 695-700
    • Yang, Y.G.1    Wood, J.C.2    Lan, P.3    Wilkinson, R.A.4    Sykes, M.5    Fishman, J.A.6
  • 29
    • 0141798566 scopus 로고    scopus 로고
    • Immunopathology of human T cell responses to skin, artery and endothelial cell grafts in the human peripheral blood lymphocyte/severe combined immunodeficient mouse
    • Pober J.S., Bothwell A.L., Lorber M.I., McNiff J.M., Schechner J.S., Tellides G. Immunopathology of human T cell responses to skin, artery and endothelial cell grafts in the human peripheral blood lymphocyte/severe combined immunodeficient mouse. Springer Semin Immunopathol 2003, 25(2):167-180.
    • (2003) Springer Semin Immunopathol , vol.25 , Issue.2 , pp. 167-180
    • Pober, J.S.1    Bothwell, A.L.2    Lorber, M.I.3    McNiff, J.M.4    Schechner, J.S.5    Tellides, G.6
  • 30
    • 28544432065 scopus 로고    scopus 로고
    • Activated natural killer cells from patients with acute myeloid leukemia are cytotoxic against autologous leukemic blasts in NOD/SCID mice
    • Siegler U., Kalberer C.P., Nowbakht P., Sendelov S., Meyer-Monard S., Wodnar-Filipowicz A. Activated natural killer cells from patients with acute myeloid leukemia are cytotoxic against autologous leukemic blasts in NOD/SCID mice. Leukemia 2005, 19(12):2215-2222.
    • (2005) Leukemia , vol.19 , Issue.12 , pp. 2215-2222
    • Siegler, U.1    Kalberer, C.P.2    Nowbakht, P.3    Sendelov, S.4    Meyer-Monard, S.5    Wodnar-Filipowicz, A.6
  • 31
    • 33745138505 scopus 로고    scopus 로고
    • The anti-CD20 antibody rituximab augments the immunospecific therapeutic effectiveness of an anti-CD19 immunotoxin directed against human B-cell lymphoma
    • Flavell D.J., Warnes S.L., Bryson C.J., Field S.A., Noss A.L., Packham G., et al. The anti-CD20 antibody rituximab augments the immunospecific therapeutic effectiveness of an anti-CD19 immunotoxin directed against human B-cell lymphoma. Br J Haematol 2006, 134(2):157-170.
    • (2006) Br J Haematol , vol.134 , Issue.2 , pp. 157-170
    • Flavell, D.J.1    Warnes, S.L.2    Bryson, C.J.3    Field, S.A.4    Noss, A.L.5    Packham, G.6
  • 32
    • 0028118272 scopus 로고
    • In vivo cytokine expression in the thymus. CD3high human thymocytes are activated and already functionally differentiated in helper and cytotoxic cells
    • Vandekerckhove B.A., Barcena A., Schols D., Mohan-Peterson S., Spits H., Roncarolo M.G. In vivo cytokine expression in the thymus. CD3high human thymocytes are activated and already functionally differentiated in helper and cytotoxic cells. J Immunol 1994, 152(4):1738-1743.
    • (1994) J Immunol , vol.152 , Issue.4 , pp. 1738-1743
    • Vandekerckhove, B.A.1    Barcena, A.2    Schols, D.3    Mohan-Peterson, S.4    Spits, H.5    Roncarolo, M.G.6
  • 33
    • 1842588698 scopus 로고    scopus 로고
    • Development of a human adaptive immune system in cord blood cell-transplanted mice
    • Traggiai E., Chicha L., Mazzucchelli L., Bronz L., Piffaretti J.C., Lanzavecchia A., et al. Development of a human adaptive immune system in cord blood cell-transplanted mice. Science 2004, 304(5667):104-107.
    • (2004) Science , vol.304 , Issue.5667 , pp. 104-107
    • Traggiai, E.1    Chicha, L.2    Mazzucchelli, L.3    Bronz, L.4    Piffaretti, J.C.5    Lanzavecchia, A.6
  • 34
    • 20844432429 scopus 로고    scopus 로고
    • Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level
    • Roncador G., Brown P.J., Maestre L., Hue S., Martinez-Torrecuadrada J.L., Ling K.L., et al. Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level. Eur J Immunol 2005, 35(6):1681-1691.
    • (2005) Eur J Immunol , vol.35 , Issue.6 , pp. 1681-1691
    • Roncador, G.1    Brown, P.J.2    Maestre, L.3    Hue, S.4    Martinez-Torrecuadrada, J.L.5    Ling, K.L.6
  • 35
    • 33745817085 scopus 로고    scopus 로고
    • CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
    • Liu W., Putnam A.L., Xu-Yu Z., Szot G.L., Lee M.R., Zhu S., et al. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med 2006, 203(7):1701-1711.
    • (2006) J Exp Med , vol.203 , Issue.7 , pp. 1701-1711
    • Liu, W.1    Putnam, A.L.2    Xu-Yu, Z.3    Szot, G.L.4    Lee, M.R.5    Zhu, S.6
  • 36
    • 0037026003 scopus 로고    scopus 로고
    • Phenotype, localization, and mechanism of suppression of CD4+CD25+ human thymocytes
    • Annunziato F., Cosmi L., Liotta F., Lazzeri E., Manetti R., Vanini V., et al. Phenotype, localization, and mechanism of suppression of CD4+CD25+ human thymocytes. J Exp Med 2002, 196(3):379-387.
    • (2002) J Exp Med , vol.196 , Issue.3 , pp. 379-387
    • Annunziato, F.1    Cosmi, L.2    Liotta, F.3    Lazzeri, E.4    Manetti, R.5    Vanini, V.6
  • 37
    • 0036284229 scopus 로고    scopus 로고
    • Characterization of human CD25+CD4+ T cells in thymus, cord and adult blood
    • Wing K., Ekmark A., Karlsson H., Rudin A., Suri-Payer E. Characterization of human CD25+CD4+ T cells in thymus, cord and adult blood. Immunology 2002, 106(2):190-199.
    • (2002) Immunology , vol.106 , Issue.2 , pp. 190-199
    • Wing, K.1    Ekmark, A.2    Karlsson, H.3    Rudin, A.4    Suri-Payer, E.5
  • 38
    • 22844451603 scopus 로고    scopus 로고
    • Human CD4+CD25+ regulatory T cells suppress anti-porcine xenogeneic responses
    • Porter C.M., Bloom E.T. Human CD4+CD25+ regulatory T cells suppress anti-porcine xenogeneic responses. Am J Transplant 2005, 5(8):2052-2057.
    • (2005) Am J Transplant , vol.5 , Issue.8 , pp. 2052-2057
    • Porter, C.M.1    Bloom, E.T.2
  • 39
    • 33846900430 scopus 로고    scopus 로고
    • Deficient CD4+CD25high T regulatory cell function in patients with active systemic lupus erythematosus
    • Valencia X., Yarboro C., Illei G., Lipsky P.E. Deficient CD4+CD25high T regulatory cell function in patients with active systemic lupus erythematosus. J Immunol 2007, 178(4):2579-2588.
    • (2007) J Immunol , vol.178 , Issue.4 , pp. 2579-2588
    • Valencia, X.1    Yarboro, C.2    Illei, G.3    Lipsky, P.E.4
  • 40
    • 12144249838 scopus 로고    scopus 로고
    • Defective suppressor function in CD4+CD25+ T-cells from patients with type 1 diabetes
    • Lindley S., Dayan C.M., Bishop A., Roep B.O., Peakman M., Tree T.I. Defective suppressor function in CD4+CD25+ T-cells from patients with type 1 diabetes. Diabetes 2005, 54(1):92-99.
    • (2005) Diabetes , vol.54 , Issue.1 , pp. 92-99
    • Lindley, S.1    Dayan, C.M.2    Bishop, A.3    Roep, B.O.4    Peakman, M.5    Tree, T.I.6
  • 41
    • 34249080354 scopus 로고    scopus 로고
    • Humanized NOD/LtSz-scid IL2 receptor common gamma chain knockout mice in diabetes research
    • Shultz L.D., Pearson T., King M., Giassi L., Carney L., Gott B., et al. Humanized NOD/LtSz-scid IL2 receptor common gamma chain knockout mice in diabetes research. Ann N Y Acad Sci 2007, 1103:77-89.
    • (2007) Ann N Y Acad Sci , vol.1103 , pp. 77-89
    • Shultz, L.D.1    Pearson, T.2    King, M.3    Giassi, L.4    Carney, L.5    Gott, B.6
  • 42
    • 71849115053 scopus 로고    scopus 로고
    • Mouse models with human immunity and their application in biomedical research
    • Zhang B., Duan Z., Zhao Y. Mouse models with human immunity and their application in biomedical research. J Cell Mol Med 2008.
    • (2008) J Cell Mol Med
    • Zhang, B.1    Duan, Z.2    Zhao, Y.3
  • 43
    • 33751187613 scopus 로고    scopus 로고
    • Presence of functional mouse regulatory CD4+CD25+T cells in xenogeneic neonatal porcine thymus-grafted athymic mice
    • Sun Z., Zhao L., Wang H., Sun L., Yi H., Zhao Y. Presence of functional mouse regulatory CD4+CD25+T cells in xenogeneic neonatal porcine thymus-grafted athymic mice. Am J Transplant 2006, 6(12):2841-2850.
    • (2006) Am J Transplant , vol.6 , Issue.12 , pp. 2841-2850
    • Sun, Z.1    Zhao, L.2    Wang, H.3    Sun, L.4    Yi, H.5    Zhao, Y.6
  • 44
    • 60449085692 scopus 로고    scopus 로고
    • Deficiency of Mouse CD4+CD25+Foxp3+ Regulatory T Cells in Xenogeneic Pig Thymus-Grafted Nude Mice Suffering from Autoimmune Diseases
    • Zhang B.J., Sun C.M., Qu Y.Y., Zhang A.J., Liu J., Zhang L.J., et al. Deficiency of Mouse CD4+CD25+Foxp3+ Regulatory T Cells in Xenogeneic Pig Thymus-Grafted Nude Mice Suffering from Autoimmune Diseases. Cell Mol Immunol 2008, 5(5):325-332.
    • (2008) Cell Mol Immunol , vol.5 , Issue.5 , pp. 325-332
    • Zhang, B.J.1    Sun, C.M.2    Qu, Y.Y.3    Zhang, A.J.4    Liu, J.5    Zhang, L.J.6
  • 45
    • 71849094573 scopus 로고    scopus 로고
    • Abnormal Regulatory and Effector T Cell Function Predispose to Autoimmunity following Xenogeneic Thymic Transplantation
    • Fudaba Y., Onoe T., Chittenden M., Shimizu A., Shaffer J.M., Bronson R., et al. Abnormal Regulatory and Effector T Cell Function Predispose to Autoimmunity following Xenogeneic Thymic Transplantation. J Immunol 2008, 181(11):7649-7659.
    • (2008) J Immunol , vol.181 , Issue.11 , pp. 7649-7659
    • Fudaba, Y.1    Onoe, T.2    Chittenden, M.3    Shimizu, A.4    Shaffer, J.M.5    Bronson, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.