Neurophysiological and behavioral effects of tDCS combined with constraint-induced movement therapy in poststroke patients

Neurorehabilitation and Neural Repair

Volumn 25, Issue 9, 2011, Pages 819-829

  Bolognini, Nadia ^a,b,c   Vallar, Giuseppe ^b,c   Casati, Carlotta ^b,c   Latif, Lydia Abdul ^a,d   El Nazer, Rasheda ^a   Williams, Julie ^a   Banco, Elisabetta ^c   MacEa, Debora Duarte ^a   Tesio, Luigi ^c,e   Chessa, Cecilia ^c   Fregni, Felipe ^f  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MILANO BICOCCA   (Italy)

^c ISTITUTO AUXOLOGICO ITALIANO   (Italy)

^d UNIVERSITY OF MALAYA   (Malaysia)

^e UNIVERSITY OF MILAN   (Italy)

^f and Red Sox Foundation and Massachusetts General Hospital Home Base Program   (United States)

Author keywords

constraint induced movement therapy; motor cortex; motor recovery; stroke rehabilitation; transcranial direct current stimulation

Indexed keywords

ADULT; AGED; ARTICLE; CHRONIC BRAIN DISEASE; CLINICAL ARTICLE; CONSTRAINT INDUCED THERAPY; CONTROLLED STUDY; CORPUS CALLOSUM; DOUBLE BLIND PROCEDURE; EVOKED CORTICAL RESPONSE; EXPLORATORY RESEARCH; FEMALE; GRIP STRENGTH; HAND FUNCTION; HUMAN; MALE; MOTOR ACTIVITY; MOTOR CORTEX; MOTOR PERFORMANCE; NERVE EXCITABILITY; OUTCOME ASSESSMENT; PYRAMIDAL TRACT; RATING SCALE; SHAM PROCEDURE; STROKE; STROKE PATIENT; TRANSCRANIAL DIRECT CURRENT STIMULATION;

ADULT; AGED; COMBINED MODALITY THERAPY; DOUBLE-BLIND METHOD; ELECTRIC STIMULATION THERAPY; EXERCISE THERAPY; FEMALE; HUMANS; MALE; MIDDLE AGED; MOVEMENT DISORDERS; STROKE; TRANSCRANIAL MAGNETIC STIMULATION;

EID: 80054051053     PISSN: 15459683     EISSN: 15526844     Source Type: Journal    
DOI: 10.1177/1545968311411056     Document Type: Article

References (50)

1. Lghorne P, Coupar F, Pollock A. Motor recovery after stroke: a systematic review. Lancet Neurol. 2009 ; 8: 741-754
2. Piron L, Turolla A, Agostini M, et al. Motor learning principles for rehabilitation: a pilot randomized controlled study in poststroke patients. Neurorehabil Neural Repair. 2010 ; 24: 501-508
3. Pascual-Leone A, Amedi A, Fregni F, Merabet LB. The plastic human brain cortex. Annu Rev Neurosci.. 2005 ; 28: 377-401 (Pubitemid 41098910)
4. French B, Thomas L, Leathley M, et al. Does repetitive task training improve functional activity after stroke? A Cochrane systematic review and meta-analysis. J Rehabil Med.. 2010 ; 42: 9-14
5. Dimyan MA, Cohen LG. Contribution of transcranial magnetic stimulation to the understanding of functional recovery mechanisms after stroke. Neurorehabil Neural Repair. 2010 ; 24: 125-135
6. Fregni F, Pascual-Leone A. Technology insight: noninvasive brain stimulation in neurology-perspectives on the therapeutic potential of rTMS and tDCS. Nat Clin Pract Neurol. 2007 ; 3: 383-393 (Pubitemid 47040328)
7. Nowak DA, Grefkes C, Ameli M, Fink GR. Interhemispheric competition after stroke: brain stimulation to enhance recovery of function of the affected hand. Neurorehabil Neural Repair. 2009 ; 23: 641-656
8. Lindenberg R, Renga V, Zhu LL, Nair D, Schlaug G. Bihemispheric brain stimulation facilitates motor recovery in chronic stroke patients. Neurology. 2010 ; 75: 2176-2184
9. Williams JA, Imamura M, Fregni F. Updates on the use of non-invasive brain stimulation in physical and rehabilitation medicine. J Rehabil Med.. 2009 ; 41: 305-311
10. Bolognini N, Pascual-Leone A, Fregni F. Using non-invasive brain stimulation to augment motor training-induced plasticity. J Neuroeng Rehabil.. 2009 ; 6: 8
11. Reis J, Schambra HM, Cohen LG, et al. Noninvasive cortical stimulation enhances motor skill acquisition over multiple days through an effect on consolidation. Proc Natl Acad Sci U S A. 2009 ; 106: 1590-1595
12. Rioult-Pedotti MS, Friedman D, Donoghue JP. Learning-induced LTP in neocortex. Science. 2000 ; 290: 533-536
13. Williams JA, Pascual-Leone A, Fregni F. Interhemispheric modulation induced by cortical stimulation and motor training. Phys Ther.. 2010 ; 90: 398-410
14. Tesio L. From neuroplastic potential to actual recovery after stroke: a call for cooperation between drugs and exercise. Aging (Milano). 1991 ; 3: 97-98
15. Carmichael ST. Targets for neural repair therapies after stroke. Stroke. 2010 ; 41 (10 suppl). S124 - S126
16. Wittenberg GF, Bastings EP, Fowlkes A, Morgan TM, Good DC, Pons TP. Dynamic course of intracortical TMS paired-pulse responses during recovery of motor function after stroke. Neurorehabil Neural Repair. 2007 ; 21: 568-573 (Pubitemid 47585200)
17. Witte OW, Stoll G. Delayed and remote effects of focal cortical infarctions: secondary damage and reactive plasticity. Adv Neurol.. 1997 ; 73: 207-227
18. Mark VW, Taub E. Constraint-induced movement therapy for chronic stroke hemiparesis and other disabilities. Restor Neurol Neurosci.. 2004 ; 22: 317-336 (Pubitemid 39468288)
19. Lin KC, Wu CY, Liu JS, Chen YT, Hsu CJ. Constraint-induced therapy versus dose-matched control intervention to improve motor ability, basic daily function, and quality of life in stroke. Neurorehabil Neural Repair. 2009 ; 23: 160-165
20. Liepert J. Motor cortex excitability in stroke before and after constraint-induced movement therapy. Cogn Behav Neurol. 2006 ; 19: 41-47
21. Liepert J, Bauder H, Wolfgang HR, Miltner WH, Taub E, Weiller C. Treatment-induced cortical reorganization after stroke in humans. Stroke. 2000 ; 31: 1210-1216 (Pubitemid 30351235)
22. Wolf SL, Winstein CJ, Miller JP, et al. Effect of constraint-induced movement therapy on upper extremity function 3 to 9 months after stroke: the EXCITE randomized clinical trial. JAMA. 2006 ; 296: 2095-2104 (Pubitemid 44664704)
23. Rossi S, Hallett M, Rossini PM, Pascual-Leone A. Safety, ethical considerations, and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research. Clin Neurophysiol.. 2009 ; 120: 2008-2039
24. Taub E, Crago JE, Uswatte G. Constraint induced movement therapy: a new approach to treatment in physical medicine. Rehabil Psychol.. 1998 ; 43: 152-170 (Pubitemid 28360004)
25. Jebsen RH, Taylor N, Trieschmann RB, Trotter MJ, Howard LA. An objective and standardized test of hand function. Arch Phys Med Rehabil. 1969 ; 50: 311-319
26. Mathiowetz V, Kashman N, Volland G, Weber K, Dowe M, Rogers S. Grip and pinch strength: normative data for adults. Arch Phys Med Rehabil. 1985 ; 66: 69-74 (Pubitemid 15134048)
27. Park SW, Wolf SL, Blanton S, Winstein C, Nichols- Larsen DS. The EXCITE Trial: predicting a clinically meaningful motor activity log outcome. Neurorehabil Neural Repair. 2008 ; 22: 486-493
28. Fugl-Meyer AR, Jaasko L, Leyman I, Olsson S, Steglind S. The post-stroke hemiplegic patient. 1. A method for evaluation of physical performance. Scand J Rehabil Med.. 1975 ; 7: 13-31
29. Mahoney FI, Barthel D. Functional evaluation: the Barthel Index. Md State Med J.. 1965 ; 14: 56-61
30. Beck AT, Ward C, Mendelson M. Beck Depression Inventory (BDI). Arch Gen Psychiatry. 1961 ; 4: 561-571
31. Folstein MF, Folstein SE, McHugh PR. Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res.. 1975 ; 12: 189-198
32. Wassermann EM, Epstein CM, Ziemann U, Walsh V, Paus T, Lisanby SH The Oxford Handbook of Transcranial Stimulation. New York, NY: Oxford University Press ; 2008 :
33. Bonaiuti D, Rebasti L, Sioli P. The constraint induced movement therapy: a systematic review of randomised controlled trials on the adult stroke patients. Eura Medicophys. 2007 ; 43: 139-146
34. Taub E, Crago JE, Burgio LD, et al. An operant approach to rehabilitation medicine: overcoming learned nonuse by shaping. J Exp Anal Behav.. 1994 ; 61: 281-293
35. Gandiga PC, Hummel FC, Cohen LG. Transcranial DC stimulation (tDCS): a tool for double-blind sham-controlled clinical studies in brain stimulation. Clin Neurophysiol. 2006 ; 117: 845-850
36. Nitsche MA, Liebetanz D, Lang N, Antal A, Tergau F, Paulus W. Safety criteria for transcranial direct current stimulation (tDCS) in humans. Clin Neurophysiol.. 2003 ; 114: 2220-2222
37. Cohen J. Eta-squared and partial eta-squared in fixed factor ANOVA designs. Educ Psychol Meas.. 1973 ; 33: 107-112
38. Cohen J, West SG, Cohen P, Aiken L Applied Multiple Regression/ Correlation Analysis for the Behavioral Sciences. 3 rd ed.Mahwah, NJ: Erlbaum; 2002. Mahwah, NJ: Erlbaum ; 2002 :
39. Lind K. A synthesis of studies on stroke rehabilitation. J Chronic Dis.. 1982 ; 35: 133-149 (Pubitemid 12172294)
40. Nitsche MA, Seeber A, Frommann K, et al. Modulating parameters of excitability during and after transcranial direct current stimulation of the human motor cortex. J Physiol.. 2005 ; 568: 291-303 (Pubitemid 41448638)
41. Fregni F, Boggio PS, Valle AC, et al. A sham-controlled trial of a 5-day course of repetitive transcranial magnetic stimulation of the unaffected hemisphere in stroke patients. Stroke. 2006 ; 37: 2115-2122 (Pubitemid 44309913)
42. Hummel F, Celnik P, Giraux P, et al. Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke. Brain. 2005 ; 128: 490-499 (Pubitemid 40380185)
43. Muller K, Homberg V, Coppenrath P, Lenard HG. Maturation of set-modulation of lower extremity EMG responses to postural perturbations. Neuropediatrics. 1992 ; 23: 82-91
44. Jancke L, Steinmetz H, Benilow S, Ziemann U. Slowing fastest finger movements of the dominant hand with low- frequency rTMS of the hand area of the primary motor cortex. Exp Brain Res.. 2004 ; 155: 196-203 (Pubitemid 38388731)
45. Galea JM, Celnik P. Brain polarization enhances the formation and retention of motor memories. J Neurophysiol.. 2009 ; 102: 294-301
46. Hesse S, Werner C, Schonhardt EM, Bardeleben A, Jenrich W, Kirker S. Combined transcranial direct current stimulation and robot-assisted arm training in subacute stroke patients: a pilot study. Restor Neurol Neurosci.. 2007 ; 25: 9-15 (Pubitemid 46631009)
47. Edwards DJ, Krebs HI, Rykman A, et al. Raised corticomotor excitability of M1 forearm area following anodal tDCS is sustained during robotic wrist therapy in chronic stroke. Restor Neurol Neurosci.. 2009 ; 27: 199-207
48. Thickbroom GW. Transcranial magnetic stimulation and synaptic plasticity: experimental framework and human models. Exp Brain Res.. 2007 ; 180: 583-593 (Pubitemid 46988122)
49. Hebb DO The Organization of Behavior. A Neuropsychological Theory. New York, NY: Wiley ; 1949 :
50. Ameli M, Grefkes C, Kemper F, et al. Differential effects of high-frequency repetitive transcranial magnetic stimulation over ipsilesional primary motor cortex in cortical and subcortical middle cerebral artery stroke. Ann Neurol. 2009 ; 66: 298-309