Imaging of lytic granule exocytosis in CD8+ cytotoxic T lymphocytes reveals a modified form of full fusion

Cellular Immunology

Volumn 271, Issue 2, 2011, Pages 267-279

  Martina, Jose A ^a   Wu, Xufeng S ^a   Catalfamo, Marta ^b   Sakamoto, Takeshi ^c   Yi, Chang ^a   Hammer, John A ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c WAYNE STATE UNIVERSITY   (United States)

Author keywords

Cytotoxic T lymphocyte; Exocytosis; Granzyme; Lytic granule; Serglycin; TIRF imaging

Indexed keywords

CATHEPSIN D; CD3 ANTIBODY; GRANZYME A; GRANZYME B; INTERLEUKIN 15; INTERLEUKIN 2; IONOMYCIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MONOCLONAL ANTIBODY CD28; PHORBOL ESTER; PROTEOGLYCAN; SERGLYCIN; UNCLASSIFIED DRUG;

ARTICLE; CD8+ T LYMPHOCYTE; CELL GRANULE; CELL LABELING; CELL MEMBRANE; CELL VACUOLE; CYTOTOXIC T LYMPHOCYTE; DIFFUSION; EXOCYTOSIS; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; LYSIS; MICROSCOPY; MOUSE; NONHUMAN; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TOTAL INTERNAL REFLECTION MICROSCOPY;

ANIMALS; EXOCYTOSIS; GRANZYMES; GREEN FLUORESCENT PROTEINS; HUMANS; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; MEMBRANE FUSION; MICE; MICROSCOPY, FLUORESCENCE; PROTEOGLYCANS; RECOMBINANT FUSION PROTEINS; SECRETORY VESICLES; T-LYMPHOCYTES, CYTOTOXIC; VESICULAR TRANSPORT PROTEINS;

EID: 80054030847     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2011.07.004     Document Type: Article

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