-
1
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP et al (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139(5): 871-890.
-
(2009)
Cell
, vol.139
, Issue.5
, pp. 871-890
-
-
Thiery, J.P.1
-
2
-
-
51049114514
-
Twisted epithelial-mesenchymal transition blocks senescence
-
Weinberg RA (2008) Twisted epithelial-mesenchymal transition blocks senescence. Nat Cell Biol 10(9): 1021-1023.
-
(2008)
Nat Cell Biol
, vol.10
, Issue.9
, pp. 1021-1023
-
-
Weinberg, R.A.1
-
3
-
-
63049123066
-
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
-
Polyak K, Weinberg RA (2009) Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 9(4): 265-273.
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.4
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
4
-
-
21344467705
-
Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells
-
Yang S et al (2005) Diverse biological effect and Smad signaling of bone morphogenetic protein 7 in prostate tumor cells. Cancer Res 65(13): 5769-5777.
-
(2005)
Cancer Res
, vol.65
, Issue.13
, pp. 5769-5777
-
-
Yang, S.1
-
5
-
-
36048996006
-
Fibroblast mechanics in 3D collagen matrices
-
Rhee S, Grinnell F (2007) Fibroblast mechanics in 3D collagen matrices. Adv Drug Deliv Rev 59(13): 1299-1305.
-
(2007)
Adv Drug Deliv Rev
, vol.59
, Issue.13
, pp. 1299-1305
-
-
Rhee, S.1
Grinnell, F.2
-
6
-
-
0037603113
-
Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
-
Debnath J, Muthuswamy SK, Brugge JS (2003) Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 30(3): 256-268.
-
(2003)
Methods
, vol.30
, Issue.3
, pp. 256-268
-
-
Debnath, J.1
Muthuswamy, S.K.2
Brugge, J.S.3
-
7
-
-
79952000716
-
3D models of epithelial-mesenchymal transition in breast cancer metastasis: high-throughput screening assay development, validation, and pilot screen
-
Li Q et al (2011) 3D models of epithelial-mesenchymal transition in breast cancer metastasis: high-throughput screening assay development, validation, and pilot screen. J Biomol Screen 16(2): 141-154.
-
(2011)
J Biomol Screen
, vol.16
, Issue.2
, pp. 141-154
-
-
Li, Q.1
-
8
-
-
27844461512
-
Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways
-
Larue L, Bellacosa A (2005) Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways. Oncogene 24(50): 7443-7454.
-
(2005)
Oncogene
, vol.24
, Issue.50
, pp. 7443-7454
-
-
Larue, L.1
Bellacosa, A.2
-
9
-
-
0034711307
-
Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration
-
Bakin AV et al (2000) Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration. J Biol Chem 275(47): 36803-36810.
-
(2000)
J Biol Chem
, vol.275
, Issue.47
, pp. 36803-36810
-
-
Bakin, A.V.1
-
10
-
-
77956287380
-
A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses
-
Harma V et al (2010) A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses. PLoS One 5(5): e10431.
-
(2010)
PLoS One
, vol.5
, Issue.5
-
-
Harma, V.1
-
11
-
-
78650193523
-
Mouse prostate cancer cell lines established from primary and post-castration recurrent tumors
-
Liao CP et al (2010) Mouse prostate cancer cell lines established from primary and post-castration recurrent tumors. Horm Cancer 1(1): 44-54.
-
(2010)
Horm Cancer
, vol.1
, Issue.1
, pp. 44-54
-
-
Liao, C.P.1
-
12
-
-
75949085815
-
Runx2 regulates survivin expression in prostate cancer cells
-
Lim M et al (2009) Runx2 regulates survivin expression in prostate cancer cells. Lab Invest 90: 222-233.
-
(2009)
Lab Invest
, vol.90
, pp. 222-233
-
-
Lim, M.1
-
13
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
-
Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25(4): 402-408.
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
14
-
-
0025818032
-
Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role
-
Vleminckx K et al (1991) Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 66(1): 107-119.
-
(1991)
Cell
, vol.66
, Issue.1
, pp. 107-119
-
-
Vleminckx, K.1
-
15
-
-
0023225108
-
Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA
-
Nagafuchi A et al (1987) Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA. Nature 329(6137): 341-343.
-
(1987)
Nature
, vol.329
, Issue.6137
, pp. 341-343
-
-
Nagafuchi, A.1
-
16
-
-
4043052971
-
Epithelial-mesenchymal transitions: twist in development and metastasis
-
Kang Y, Massague J (2004) Epithelial-mesenchymal transitions: twist in development and metastasis. Cell 118(3): 277-279.
-
(2004)
Cell
, vol.118
, Issue.3
, pp. 277-279
-
-
Kang, Y.1
Massague, J.2
-
17
-
-
2942707848
-
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
-
Yang J et al (2004) Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 117(7): 927-939.
-
(2004)
Cell
, vol.117
, Issue.7
, pp. 927-939
-
-
Yang, J.1
-
18
-
-
21244437500
-
Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer
-
Martin TA et al (2005) Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer. Ann Surg Oncol 12(6): 488-496.
-
(2005)
Ann Surg Oncol
, vol.12
, Issue.6
, pp. 488-496
-
-
Martin, T.A.1
-
19
-
-
24644487312
-
TGF-beta and epithelial-to-mesenchymal transitions
-
Zavadil J, Bottinger EP (2005) TGF-beta and epithelial-to-mesenchymal transitions. Oncogene 24(37): 5764-5774.
-
(2005)
Oncogene
, vol.24
, Issue.37
, pp. 5764-5774
-
-
Zavadil, J.1
Bottinger, E.P.2
-
20
-
-
0034964418
-
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion
-
Comijn J et al (2001) The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. Mol Cell 7(6): 1267-1278.
-
(2001)
Mol Cell
, vol.7
, Issue.6
, pp. 1267-1278
-
-
Comijn, J.1
-
21
-
-
20444453337
-
Up-regulation of TWIST in prostate cancer and its implication as a therapeutic target
-
Kwok WK et al (2005) Up-regulation of TWIST in prostate cancer and its implication as a therapeutic target. Cancer Res 65(12): 5153-5162.
-
(2005)
Cancer Res
, vol.65
, Issue.12
, pp. 5153-5162
-
-
Kwok, W.K.1
-
23
-
-
37249010753
-
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
-
Yu PB et al (2008) Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol 4(1): 33-41.
-
(2008)
Nat Chem Biol
, vol.4
, Issue.1
, pp. 33-41
-
-
Yu, P.B.1
-
24
-
-
0035902849
-
Prostate epithelial cell lines form spheroids with evidence of glandular differentiation in three-dimensional Matrigel cultures
-
Lang SH et al (2001) Prostate epithelial cell lines form spheroids with evidence of glandular differentiation in three-dimensional Matrigel cultures. Br J Cancer 85(4): 590-599.
-
(2001)
Br J Cancer
, vol.85
, Issue.4
, pp. 590-599
-
-
Lang, S.H.1
-
25
-
-
0035698420
-
Experimental prostate epithelial morphogenesis in response to stroma and three-dimensional matrigel culture
-
Lang SH et al (2001) Experimental prostate epithelial morphogenesis in response to stroma and three-dimensional matrigel culture. Cell Growth Differ 12(12): 631-640.
-
(2001)
Cell Growth Differ
, vol.12
, Issue.12
, pp. 631-640
-
-
Lang, S.H.1
-
26
-
-
67649528138
-
Collective cell migration in morphogenesis, regeneration and cancer
-
Friedl P, Gilmour D (2009) Collective cell migration in morphogenesis, regeneration and cancer. Nat Rev Mol Cell Biol 10(7): 445-457.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, Issue.7
, pp. 445-457
-
-
Friedl, P.1
Gilmour, D.2
-
27
-
-
70449526719
-
Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility
-
Giampieri S et al (2009) Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility. Nat Cell Biol 11(11): 1287-1296.
-
(2009)
Nat Cell Biol
, vol.11
, Issue.11
, pp. 1287-1296
-
-
Giampieri, S.1
-
28
-
-
50249092881
-
Osteoblasts-derived BMP-2 enhances the motility of prostate cancer cells via activation of integrins
-
Lai TH et al (2008) Osteoblasts-derived BMP-2 enhances the motility of prostate cancer cells via activation of integrins. Prostate 68(12): 1341-1353.
-
(2008)
Prostate
, vol.68
, Issue.12
, pp. 1341-1353
-
-
Lai, T.H.1
-
29
-
-
0037728809
-
The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines
-
Grille SJ et al (2003) The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. Cancer Res 63(9): 2172-2178.
-
(2003)
Cancer Res
, vol.63
, Issue.9
, pp. 2172-2178
-
-
Grille, S.J.1
-
30
-
-
6944248910
-
Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro
-
Xie L et al (2004) Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro. Neoplasia 6(5): 603-610.
-
(2004)
Neoplasia
, vol.6
, Issue.5
, pp. 603-610
-
-
Xie, L.1
-
31
-
-
0035185853
-
Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism
-
Bhowmick NA et al (2001) Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism. Mol Biol Cell 12(1): 27-36.
-
(2001)
Mol Biol Cell
, vol.12
, Issue.1
, pp. 27-36
-
-
Bhowmick, N.A.1
-
32
-
-
0642306119
-
Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line
-
Xie L et al (2003) Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line. Breast Cancer Res 5(6): R187-R198.
-
(2003)
Breast Cancer Res
, vol.5
, Issue.6
, pp. 187-198
-
-
Xie, L.1
-
33
-
-
76849112495
-
Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions
-
Akech J et al (2010) Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions. Oncogene 29(6): 811-821.
-
(2010)
Oncogene
, vol.29
, Issue.6
, pp. 811-821
-
-
Akech, J.1
-
34
-
-
0033587156
-
Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasis
-
Miyaki M et al (1999) Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasis. Oncogene 18(20): 3098-3103.
-
(1999)
Oncogene
, vol.18
, Issue.20
, pp. 3098-3103
-
-
Miyaki, M.1
-
35
-
-
3543143101
-
Functional proteomics mapping of a human signaling pathway
-
Colland F et al (2004) Functional proteomics mapping of a human signaling pathway. Genome Res 14(7): 1324-1332.
-
(2004)
Genome Res
, vol.14
, Issue.7
, pp. 1324-1332
-
-
Colland, F.1
-
36
-
-
54549102135
-
Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway
-
Katsuno Y et al (2008) Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway. Oncogene 27(49): 6322-6333.
-
(2008)
Oncogene
, vol.27
, Issue.49
, pp. 6322-6333
-
-
Katsuno, Y.1
-
37
-
-
33748059537
-
Transforming growth factor-beta promotes invasion in tumorigenic but not in nontumorigenic human prostatic epithelial cells
-
Ao M et al (2006) Transforming growth factor-beta promotes invasion in tumorigenic but not in nontumorigenic human prostatic epithelial cells. Cancer Res 66(16): 8007-8016.
-
(2006)
Cancer Res
, vol.66
, Issue.16
, pp. 8007-8016
-
-
Ao, M.1
-
38
-
-
59849124087
-
Development of a three-dimensional culture model of prostatic epithelial cells and its use for the study of epithelial-mesenchymal transition and inhibition of PI3K pathway in prostate cancer
-
Chu JH et al (2009) Development of a three-dimensional culture model of prostatic epithelial cells and its use for the study of epithelial-mesenchymal transition and inhibition of PI3K pathway in prostate cancer. Prostate 69(4): 428-442.
-
(2009)
Prostate
, vol.69
, Issue.4
, pp. 428-442
-
-
Chu, J.H.1
-
39
-
-
34548705794
-
BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo
-
Buijs JT et al (2007) BMP7, a putative regulator of epithelial homeostasis in the human prostate, is a potent inhibitor of prostate cancer bone metastasis in vivo. Am J Pathol 171(3): 1047-1057.
-
(2007)
Am J Pathol
, vol.171
, Issue.3
, pp. 1047-1057
-
-
Buijs, J.T.1
-
40
-
-
0030223057
-
Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice
-
Pettaway CA et al (1996) Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice. Clin Cancer Res 2(9): 1627-1636.
-
(1996)
Clin Cancer Res
, vol.2
, Issue.9
, pp. 1627-1636
-
-
Pettaway, C.A.1
-
41
-
-
76749108468
-
Bone morphogenetic protein 7 is expressed in prostate cancer metastases and its effects on prostate tumor cells depend on cell phenotype and the tumor microenvironment
-
Morrissey C et al (2010) Bone morphogenetic protein 7 is expressed in prostate cancer metastases and its effects on prostate tumor cells depend on cell phenotype and the tumor microenvironment. Neoplasia 12(2): 192-205.
-
(2010)
Neoplasia
, vol.12
, Issue.2
, pp. 192-205
-
-
Morrissey, C.1
|