CEACAM1 creates a pro-angiogenic tumor microenvironment that supports tumor vessel maturation

Oncogene

Volumn 30, Issue 41, 2011, Pages 4275-4288

  Gerstel, D ^a   Wegwitz, F ^b   Jannasch, K ^c   Ludewig, P ^a   Scheike, K ^a   Alves, F ^c   Beauchemin, N ^d   Deppert, W ^b   Wagener, C ^a   Horst, A K ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

^c UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

angiogenesis; CEACAM1; MMP9 expressing leukocytes; tumor microenvironments; vessel maturation

Indexed keywords

ANGIOPOIETIN RECEPTOR; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; COLLAGEN TYPE 4; GELATINASE B; MILK PROTEIN;

ACCESSORY CELL; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST ADENOCARCINOMA; BREAST CARCINOGENESIS; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HISTOLOGY; LEUKOCYTE; LUNG METASTASIS; MOUSE; NONHUMAN; NULL ALLELE; ONCOGENE; ORTHOTOPIC TRANSPLANTATION; PERICYTE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STROMA CELL; TRANSGENIC MOUSE; TRANSGENICS; TUMOR MICROENVIRONMENT; TUMOR VASCULARIZATION;

ANIMALS; ANTIGENS, CD; ANTIGENS, POLYOMAVIRUS TRANSFORMING; BLOOD VESSELS; BLOTTING, WESTERN; CARCINOEMBRYONIC ANTIGEN; CELL ADHESION MOLECULES; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; LEUKOCYTES; LUNG NEOPLASMS; MALE; MAMMARY NEOPLASMS, EXPERIMENTAL; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MILK PROTEINS; NEOVASCULARIZATION, PATHOLOGIC; PROMOTER REGIONS, GENETIC; TUMOR MICROENVIRONMENT;

MURINAE; MUS; MUS MUSCULUS;

EID: 80054017870     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.146     Document Type: Article

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