Central inflammation and sickness-like behavior induced by the food contaminant deoxynivalenol: A PGE2-independent mechanism

Toxicological Sciences

Volumn 124, Issue 1, 2011, Pages 179-191

  Girardet, Clémence ^a   Bonnet, Marion S ^a   Jdir, Rajae ^a   Sadoud, Medhi ^a   Thirion, Sylvie ^b   Tardivel, Catherine ^a   Roux, Julien ^c   Lebrun, Bruno ^a   Mounien, Lourdes ^a   Trouslard, Jérôme ^a   Jean, André ^a   Dallaporta, Michel ^a   Troadec, Jean Denis ^a  

^a University of Mediterranée   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

^c Biomeostasis Contract Research Organization   (France)

Author keywords

Brain; c Fos; Cytokines; mPGES 1; Mycotoxin

Indexed keywords

CYCLOOXYGENASE 2; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; MICROSOMAL PROSTAGLANDIN SYNTHASE 1; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PROTEIN C FOS; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VOMITOXIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; CELL POPULATION; CEREAL; CONTROLLED STUDY; COOKING; FEEDING BEHAVIOR; FOOD CONTAMINATION; FOOD PROCESSING; INFLAMMATION; INTOXICATION; KNOCKOUT MOUSE; LOCOMOTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; NUTRITIONAL DEFICIENCY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WEIGHT REDUCTION;

ANIMALS; ANOREXIA; BODY TEMPERATURE; BRAIN; CYTOKINES; DINOPROSTONE; FOOD CONTAMINATION; GENE EXPRESSION; ILLNESS BEHAVIOR; IMMUNOHISTOCHEMISTRY; INTRAMOLECULAR OXIDOREDUCTASES; MALE; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; REAL-TIME POLYMERASE CHAIN REACTION; TRICHOTHECENES;

EID: 80054005921     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr219     Document Type: Article

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