The effect of elinogrel on high platelet reactivity during dual antiplatelet therapy and the relation to cyp 2c192 genotype: First experience in patients

Journal of Thrombosis and Haemostasis

Volumn 8, Issue 1, 2010, Pages 43-53

  Gurbel, P A ^a   Bliden, K P ^a   Antonino, M J ^a   Stephens, G ^b   Gretler, D D ^b   Jurek, M M ^b   Pakyz, R E ^c   Shuldiner, A R ^c   Conley, P B ^b   Tantry, U S ^a  

^a SINAI CENTER FOR THROMBOSIS RESEARCH   (United States)

^b Portola Pharmaceuticals Inc   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Clopidogrel; Elinogrel; P2Y12 receptor; Platelet inhibitor

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTILIPEMIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CLOPIDOGREL; CYTOCHROME P450 2C19; CYTOCHROME P450 3A5; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; ELINOGREL; INSULIN; NITRATE; PRT 060128; PURINERGIC P2Y12 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; VASODILATOR STIMULATED PHOSPHOPROTEIN;

ABSENCE OF SIDE EFFECTS; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY STENT; DIABETES MELLITUS; DRUG BLOOD LEVEL; DRUG URINE LEVEL; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; MALE; PATIENT COMPLIANCE; POSTOPERATIVE THROMBOSIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SINGLE DRUG DOSE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE AGGREGATION INHIBITION; THROMBOELASTOGRAPHY; TIME;

ADENOSINE DIPHOSPHATE; ADMINISTRATION, ORAL; AGED; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; ARYL HYDROCARBON HYDROXYLASES; ASPIRIN; BLOOD COAGULATION; BLOOD PLATELETS; CELL ADHESION MOLECULES; COLLAGEN; CORONARY ARTERY DISEASE; CYTOCHROME P-450 CYP3A; DRUG THERAPY, COMBINATION; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; MALE; MICROFILAMENT PROTEINS; MIDDLE AGED; PHENOTYPE; PHOSPHOPROTEINS; PHOSPHORYLATION; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; POLYMORPHISM, GENETIC; QUINAZOLINONES; RECEPTORS, PURINERGIC P2; STENTS; SULFONAMIDES; THROMBELASTOGRAPHY; TICLOPIDINE;

EID: 73149118496     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2009.03648.x     Document Type: Article

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