Characterization of the human gastric fluid proteome reveals distinct pH-dependent protein profiles: Implications for biomarker studies

Journal of Proteome Research

Volumn 10, Issue 10, 2011, Pages 4535-4546

  Kam, Siok Yuen ^a   Hennessy, Thomas ^b   Chua, Seow Ching ^a   Gan, Chee Sian ^b   Philp, Robin ^b   Hon, Ka Ka ^a   Lai, Liyun ^a   Chan, Weng Hoong ^c   Ong, Hock Soo ^c   Wong, Wai Keong ^c   Lim, Kiat Hon ^c   Ling, Khoon Lin ^c   Tan, Hwee Sian ^b   Tan, Mei Mei ^b   Ho, Mengfatt ^a   Kon, Oi Lian ^a  

^a DIVISION OF MEDICAL ONCOLOGY   (Singapore)

^b AGILENT TECHNOLOGIES   (Singapore)

^c SINGAPORE GENERAL HOSPITAL   (Singapore)

Author keywords

biomarkers; gastric cancer; gastric juice; HPLC Chip MS; mass spectrometry; multidimensional LC MS MS; two dimensional gel electrophoresis (2 DE)

Indexed keywords

ALPHA 1 ANTITRYPSIN; BIOLOGICAL MARKER; CARBONATE DEHYDRATASE II; CATHEPSIN D; GASTROKINE; INTESTINAL TREFOIL FACTOR; PEPSINOGEN II; TUMOR MARKER; UNCLASSIFIED DRUG;

ACIDITY; ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IMMUNOBLOTTING; LIQUID CHROMATOGRAPHY; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; STOMACH CANCER; STOMACH JUICE; STOMACH PH; TWO DIMENSIONAL ELECTROPHORESIS; ULTRACENTRIFUGATION; WESTERN BLOTTING;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENDOSCOPY; FEMALE; GASTRIC JUICE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; HYDROGEN-ION CONCENTRATION; IMMUNOBLOTTING; MALE; MASS SPECTROMETRY; MIDDLE AGED; PROTEOME; PROTEOMICS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TUMOR MARKERS, BIOLOGICAL;

EID: 80053930214     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr200349z     Document Type: Article

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