Development of a mathematical model for evaluating the dynamics of normal and apoptotic Chinese hamster ovary cells

Biotechnology Progress

Volumn 27, Issue 5, 2011, Pages 1197-1205

  Naderi, Saeideh ^a   Meshram, Mukesh ^a   Wei, Catherine ^a   Mcconkey, Brendan ^a   Ingalls, Brian ^a   Budman, Hector ^a   Scharer, Jeno ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

Author keywords

Apoptosis; CHO; Logistic equation; Mathematical modeling; Metabolic flux analysis

Indexed keywords

APOPTOTIC; CHINESE HAMSTER OVARY CELLS; CHO; EXPERIMENTAL DATA; FED BATCHES; KINETIC RATES; LOGISTIC EQUATION; LOGISTIC MODELS; MATHEMATICAL MODELING; METABOLIC FLUX; METABOLIC FLUX ANALYSIS; METABOLIC NETWORK; MODEL BASED OPTIMIZATION; MODEL PREDICTION; MONOCLONAL ANTIBODIES (MAB); NUTRIENT CONCENTRATIONS;

CELL DEATH; DYNAMIC MODELS; METABOLISM; MONOCLONAL ANTIBODIES; PHYSIOLOGY;

BATCH CELL CULTURE;

MONOCLONAL ANTIBODY;

ANIMAL; APOPTOSIS; ARTICLE; BIOSYNTHESIS; CHO CELL; COMPARATIVE STUDY; CRICETULUS; HAMSTER; THEORETICAL MODEL; VALIDATION STUDY;

ANIMALS; ANTIBODIES, MONOCLONAL; APOPTOSIS; CHO CELLS; CRICETINAE; CRICETULUS; MODELS, THEORETICAL;

CRICETULUS GRISEUS;

EID: 80053927286     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.647     Document Type: Article

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