DAF-FM (4-amino-5-methylamino-2′,7′-difluorofluorescein) diacetate detects impairment of agonist-stimulated nitric oxide synthesis by elevated glucose in human vascular endothelial cells: Reversal by vitamin C and L-sepiapterin

Journal of Pharmacology and Experimental Therapeutics

Volumn 315, Issue 2, 2005, Pages 931-940

  Sheng, Jian Zhong ^a   Wang, Dianna ^a   Braun, Andrew P ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 5 METHYLAMINO 2',7' DIFLUOROFLUORESCEIN DIACETATE; ADENOSINE TRIPHOSPHATE; ASCORBIC ACID; CALCIMYCIN; CALCIUM IONOPHORE; FLUORESCEIN DERIVATIVE; FLUORESCENT DYE; GLUCOSE; HISTAMINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SEPIAPTERIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM CELL LEVEL; CELL LEVEL; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM; ENDOTHELIUM CELL; EXPOSURE; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; PRIORITY JOURNAL; SYNTHESIS; UMBILICAL VEIN; VASCULAR ENDOTHELIUM; VASODILATATION;

ADENOSINE TRIPHOSPHATE; ASCORBIC ACID; BIOLOGICAL AVAILABILITY; BLOTTING, WESTERN; CALCIUM; CELL LINE; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME ACTIVATION; FLUORESCEINS; GLUCOSE; HUMANS; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; PTERINS; VITAMINS;

EID: 27144476526     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.105.087932     Document Type: Article

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