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Volumn 31, Issue 7, 2011, Pages 603-607

A meta-analysis of eNOS and ACE gene polymorphisms and risk of pre-eclampsia in women

Author keywords

ACE; ENOS; Gene polymorphisms; Meta analyses; Odds ratio; Pre eclampsia

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE;

EID: 80053631373     PISSN: 01443615     EISSN: 13646893     Source Type: Journal    
DOI: 10.3109/01443615.2011.598971     Document Type: Article
Times cited : (36)

References (48)
  • 1
    • 77951945288 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase, angiotensin converting enzyme and angiotensinogen gene polymorphisms in hypertensive disorders of pregnancy
    • Aggarwal PK, Jain V, Jha V. 2010. Endothelial nitric oxide synthase, angiotensin converting enzyme and angiotensinogen gene polymorphisms in hypertensive disorders of pregnancy. Hypertension Research 33:473-477.
    • (2010) Hypertension Research , vol.33 , pp. 473-477
    • Aggarwal, P.K.1    Jain, V.2    Jha, V.3
  • 4
    • 84857238685 scopus 로고    scopus 로고
    • Available at:, (Accessed 15 March 2011)
    • Barss VA, Repke JT. 2010. Patient information: Preeclampsia. Available at: Www.uptodate.com/contents/patient-information-preeclampsia (Accessed 15 March 2011).
    • Patient Information: Preeclampsi , vol.2010
    • Barss, V.A.1    Repke, J.T.2
  • 7
    • 0019267555 scopus 로고
    • Statistical methods in cancer research. Volume I-The analysis of case-control studies
    • Breslow NE, Day NE. 1980. Statistical methods in cancer research. Volume I-the analysis of case-control studies. IARC Science Publications 32:5-338.
    • (1980) IARC Science Publications , vol.32 , pp. 5-338
    • Breslow, N.E.1    Day, N.E.2
  • 8
    • 34648828777 scopus 로고    scopus 로고
    • Polymorphisms in the endothelial nitric oxide synthase gene may be protective against preeclampsia in a Chinese population
    • Chen LK, Huang CH, Yeh HM, Lee CN, Shyu MK, Hsieh FJ et al. 2007. Polymorphisms in the endothelial nitric oxide synthase gene may be protective against preeclampsia in a Chinese population. Reproductive Sciences 14:175.
    • (2007) Reproductive Sciences , vol.14 , pp. 175
    • Chen, L.K.1    Huang, C.H.2    Yeh, H.M.3    Lee, C.N.4    Shyu, M.K.5    Hsieh, F.J.6
  • 10
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey Smith G, Schneider M, Minder C. 1997. Bias in metaanalysis detected by a simple, graphical test. British Medical Journal 315:629-634. (Pubitemid 27387172)
    • (1997) British Medical Journal , vol.315 , Issue.7109 , pp. 629-634
    • Egger, M.1    Smith, G.D.2    Schneider, M.3    Minder, C.4
  • 11
    • 80053650264 scopus 로고    scopus 로고
    • The association of angiotensinogen converting enzyme (ACE) insertion deletion polymorphism with preeclamptic women in Alexandria-Egypt
    • El Shafei SA, Zein El Din MH, Galal AF, Mokhtar MM. 2007. The association of angiotensinogen converting enzyme (ACE) insertion deletion polymorphism with preeclamptic women in Alexandria-Egypt. Egyptian Journal of Medical Human Genetics 8:57-68.
    • (2007) Egyptian Journal of Medical Human Genetics , vol.8 , pp. 57-68
    • El Shafei, S.A.1    Zein El Din, M.H.2    Galal, A.F.3    Mokhtar, M.M.4
  • 13
    • 33747475254 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase gene influences the risk of pre-eclampsia, the recurrence of negative pregnancy events, and the maternal-fetal flow
    • DOI 10.1097/01.hjh.0000242407.58159.87, PII 0000487220060900000021
    • Fatini C, Sticchia E, Gensini F, Genuardi M, Tondi F, Gensinia GF et al. 2006. Endothelial nitric oxide synthase gene influences the risk of pre-eclampsia, the recurrence of negative pregnancy events, and the maternal-fetal fl ow. Journal of Hypertension 24:1823-1829. (Pubitemid 44255484)
    • (2006) Journal of Hypertension , vol.24 , Issue.9 , pp. 1823-1829
    • Fatini, C.1    Sticchi, E.2    Gensini, F.3    Genuardi, M.4    Tondi, F.5    Gensini, G.F.6    Riviello, C.7    Parretti, E.8    Mello, G.9    Abbate, R.10
  • 15
    • 84857238302 scopus 로고    scopus 로고
    • GeneCards, Weizmann Institute of Science: Rehovot, Israel. Available at: (Accessed 15 March 2011)
    • GeneCards. 2011a. Angiotensin I converting enzyme (peptidyl-dipeptidase A) 1. Weizmann Institute of Science: Rehovot, Israel. Available at: Www.genecards.org/cgi-bin/carddisp.pl?gene- ACE (Accessed 15 March 2011).
    • (2011) Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1
  • 16
    • 84857237991 scopus 로고    scopus 로고
    • GeneCards, Weizmann Institute of Science: Rehovot, Israel. Available at: (Accessed 15 March 2011)
    • GeneCards. 2011b. Nitric oxide synthase 3 (endothelial cell). Weizmann Institute of Science: Rehovot, Israel. Available at: Www.genecards.org/cgibin/ carddisp.pl?gene -NOS3 (Accessed 15 March 2011).
    • (2011) Nitric Oxide Synthase 3 (Endothelial Cell)
  • 17
    • 84859367106 scopus 로고    scopus 로고
    • U.S. National Library of Medicine, Bethesda MD. Available at:, (Accessed 15 March 2011)
    • Genetics Home Reference. 2011. U.S. National Library of Medicine, Bethesda MD. Available at: Http://ghr.nlm.nih.gov/gene/ACE (Accessed 15 March 2011).
    • (2011) Genetics Home Reference.
  • 18
    • 1142309614 scopus 로고    scopus 로고
    • The association between preeclampsia and angiotensin-converting enzyme insertion/deletion polymorphism
    • DOI 10.1016/j.cccn.2003.11.010
    • Gurdol F, Isbilen E, Yilmaz H, Isbir T, Dirican A. 2004. The association between preeclampsia and angiotensin-converting enzyme insertion/ deletion polymorphism. Clinica Chimica Acta 341:127-131. (Pubitemid 38210323)
    • (2004) Clinica Chimica Acta , vol.341 , Issue.1-2 , pp. 127-131
    • Gurdol, F.1    Isbilen, E.2    Yilmaz, H.3    Isbir, T.4    Dirican, A.5
  • 20
  • 21
    • 25444476757 scopus 로고    scopus 로고
    • The Glu298Asp variant of the endothelial nitric oxide synthase gene is associated with an increased risk for abruptio placentae in pre-eclampsia
    • DOI 10.1007/s10038-005-0270-8
    • Hillermann R, Carelse K, Gebhardt GS. 2005. The Glu298Asp variant of the endothelial nitric oxide synthase gene is associated with an increased risk for abruptio placentae in pre-eclampsia. Journal of Human Genetics 50:415-419. (Pubitemid 41367558)
    • (2005) Journal of Human Genetics , vol.50 , Issue.8 , pp. 415-419
    • Hillermann, R.1    Carelse, K.2    Gebhardt, G.S.3
  • 22
    • 33645084003 scopus 로고    scopus 로고
    • Reduced l-arginine level and decreased placental eNOS activity in preeclampsia
    • Kim YJ, Park HS, Lee HY, Hac EH, Su SH, Ohf SK et al. 2006. Reduced l-arginine level and decreased placental eNOS activity in preeclampsia. Placenta 27:438-444.
    • (2006) Placenta , vol.27 , pp. 438-444
    • Kim, Y.J.1    Park, H.S.2    Lee, H.Y.3    Hac, E.H.4    Su, S.H.5    Ohf, S.K.6
  • 23
    • 3843144964 scopus 로고    scopus 로고
    • Associations of polymorphisms of the angiotensinogen M235 polymorphism and angiotensin-converting-enzyme intron 16 insertion/deletion polymorphism with preeclampsia in Korean women
    • DOI 10.1016/j.ejogrb.2004.01.035, PII S0301211504000879
    • Kim YJ, Park MH, Park HS, Lee KS, Ha EH, Pang MG. 2004. Associations of polymorphisms of the angiotensinogen M235 polymorphism and angiotensin- converting-enzyme intron 16 insertion/deletion polymorphism with preeclampsia in Korean women. European Journal of Obstetrics and Gynecology and Reproductive Biology 116:48-53. (Pubitemid 39044494)
    • (2004) European Journal of Obstetrics Gynecology and Reproductive Biology , vol.116 , Issue.1 , pp. 48-53
    • Kim, Y.J.1    Park, M.H.2    Park, H.S.3    Lee, K.S.4    Ha, E.H.5    Pang, M.G.6
  • 24
    • 0028349156 scopus 로고
    • Nitric oxide synthases in mammals
    • Knowles RG, Moncada S. 1994. Nitric oxide synthases in mammals. Biochemical Journal 298:249-258. (Pubitemid 24072462)
    • (1994) Biochemical Journal , vol.298 , Issue.2 , pp. 249-258
    • Knowles, R.G.1    Moncada, S.2
  • 26
    • 0035888108 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase gene (NOS3) variant and hypertension in pregnancy
    • Kobashi G, Yamada H, Ohta K, Kato E, Ebina Y, Fujimoto S. Endothelial nitric oxide synthase gene (NOS3) variant and hypertension in pregnancy. Am J Med Genet 2001;103:241-4.
    • (2001) Am J Med Genet. , vol.103 , pp. 241-4
    • Kobashi, G.1    Yamada, H.2    Ohta, K.3    Kato, E.4    Ebina, Y.5    Fujimoto, S.6
  • 28
    • 70350732618 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme and adducin-1 polymorphisms in women with preeclampsia and gestational hypertension
    • Mando C, Antonazzo P, Tabano S, Zanutto S, Pileri P, Somigliana E et al. 2009. Angiotensin-converting enzyme and adducin-1 polymorphisms in women with preeclampsia and gestational hypertension. Reproductive Sciences 16:819-826.
    • (2009) Reproductive Sciences , vol.16 , pp. 819-826
    • Mando, C.1    Antonazzo, P.2    Tabano, S.3    Zanutto, S.4    Pileri, P.5    Somigliana, E.6
  • 31
    • 52649130957 scopus 로고    scopus 로고
    • Association of angiotensin-converting enzyme insertion-deletion polymorphism with preeclampsia
    • Miskovic B, Sertic J, Stavljenic-Rukavina A, Stipoljev F. 2008. Association of angiotensin-converting enzyme insertion-deletion polymorphism with preeclampsia. Collegium Antropologicum 32:339-343.
    • (2008) Collegium Antropologicum , vol.32 , pp. 339-343
    • Miskovic, B.1    Sertic, J.2    Stavljenic-Rukavina, A.3    Stipoljev, F.4
  • 32
    • 33947723698 scopus 로고    scopus 로고
    • How Does the Maternal Immune System Contribute to the Development of Pre-eclampsia?
    • DOI 10.1016/j.placenta.2006.11.008, PII S0143400406002785
    • Moffett A, Hiby SE. 2007. How Does the maternal immune system contribute to the development of pre-eclampsia? Placenta 28: S51-S56. (Pubitemid 46506049)
    • (2007) Placenta , vol.28 , Issue.SUPPL.
    • Moffett, A.1    Hiby, S.E.2
  • 34
    • 0033066044 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme insertion-deletion polymorphism in normotensive and pre-eclamptic pregnancies
    • DOI 10.1097/00004872-199917060-00007
    • Morgan L, Foster F, Hayman R, Crawshaw S, Baker PN, Broughton Pipkin F et al. 1999b. Angiotensin-converting enzyme insertion-deletion polymorphism in normotensive and pre-eclamptic pregnancies. Journal of Hypertension 17:765-768. (Pubitemid 29322162)
    • (1999) Journal of Hypertension , vol.17 , Issue.6 , pp. 765-768
    • Morgan, L.1    Foster, F.2    Hayman, R.3    Crawshaw, S.4    Baker, P.N.5    Pipkin, F.B.6    Kalsheker, N.7
  • 36
    • 2542439029 scopus 로고    scopus 로고
    • Hypertension-related gene polymorphisms in pre-eclampsia, eclampsia and gestational hypertation in Black South African women
    • DOI 10.1097/00004872-200405000-00016
    • Roberts CB, Rom L, Moodley J, Pegoraro RJ. 2004. Hypertension-related gene polymorphisms in pre-eclampsia, eclampsia and gestational hypertension in Black South African women. Journal of Hypertension 22:945-948. (Pubitemid 38680469)
    • (2004) Journal of Hypertension , vol.22 , Issue.5 , pp. 945-948
    • Roberts, C.B.1    Rom, L.2    Moodley, J.3    Pegoraro, R.J.4
  • 37
    • 31944436638 scopus 로고    scopus 로고
    • Preeclampsia: Recent insights
    • DOI 10.1161/01.HYP.0000188408.49896.c5
    • Roberts JM, Gammill HS. 2005. Preeclampsia: Recent insights. Hypertension 46:1243-1249. (Pubitemid 43189714)
    • (2005) Hypertension , vol.46 , Issue.6 , pp. 1243-1249
    • Roberts, J.M.1    Gammill, H.S.2
  • 38
    • 60249089098 scopus 로고    scopus 로고
    • The two stage model of preeclampsia: Variations on the theme
    • Roberts JM, Hubel CA. 2009. The two stage model of preeclampsia: Variations on the theme. Placenta 30: S32-S37.
    • (2009) Placenta , vol.30
    • Roberts, J.M.1    Hubel, C.A.2
  • 39
    • 0027178149 scopus 로고
    • Pre-eclampsia: More than pregnancy-induced hypertension
    • DOI 10.1016/0140-6736(93)90889-O
    • Roberts JM, Redman CW. 1993. Pre-eclampsia: More than pregnancyinduced hypertension. Lancet 341:1447-1451. (Pubitemid 23161452)
    • (1993) Lancet , vol.341 , Issue.8858 , pp. 1447-1451
    • Roberts, J.M.1    Redman, C.W.G.2
  • 42
    • 76549135628 scopus 로고    scopus 로고
    • Role of infl ammatory cytokines and eNOS gene polymorphism in pathophysiology of pre-eclampsia
    • Singh A, Sharma D, Raghunandan C, Bhattacharjee J. 2010. Role of infl ammatory cytokines and eNOS gene polymorphism in pathophysiology of pre-eclampsia. Reproductive Immunology 63:244-251.
    • (2010) Reproductive Immunology , vol.63 , pp. 244-251
    • Singh, A.1    Sharma, D.2    Raghunandan, C.3    Bhattacharjee, J.4
  • 43
    • 0034912992 scopus 로고    scopus 로고
    • An endothelial nitric oxide synthase gene polymorphism is associated with preeclampsia
    • DOI 10.1081/PRG-100104177
    • Tempfer CB, Dorman K, Deter RL, O' Brien WE, Gregg AR. 2001. An endothelial nitric oxide synthase gene polymorphism is associated with preeclampsia. Hypertension and Pregnancy 20:107-118. (Pubitemid 32672933)
    • (2001) Hypertension in Pregnancy , vol.20 , Issue.1 , pp. 107-118
    • Tempfer, C.B.1    Dorman, K.2    Deter, R.L.3    O'Brien, W.E.4    Gregg, A.R.5
  • 44
    • 34247209761 scopus 로고    scopus 로고
    • Reduced plasma levels of angiotensin-(1-7) and renin activity in preeclamptic patients are associated with the angiotensin I converting enzyme deletion/deletion genotype
    • Velloso EP, Vieira R, Cabral AC, Kalapothakis E, Santos RAS. 2007. Reduced plasma levels of angiotensin-(1-7) and renin activity in preeclamptic patients are associated with the angiotensin I converting enzyme deletion/deletion genotype. Brazilian Journal of Medical and Biological Research 40:583-590.
    • (2007) Brazilian Journal of Medical and Biological Research , vol.40 , pp. 583-590
    • Velloso, E.P.1    Vieira, R.2    Cabral, A.C.3    Kalapothakis, E.4    Santos, R.A.S.5
  • 45
    • 0034779669 scopus 로고    scopus 로고
    • Vascular smooth muscle relaxation mediated by nitric oxide donors: A comparison with acetylcholine, nitric oxide and nitroxyl ion
    • Wanstall JC, Jeffery TK, Gambino A, Lovren F, Triggle CR. 2001. Vascular smooth muscle relaxation mediated by nitric oxide donors: A comparison with acetylcholine, nitric oxide and nitroxyl ion. British Journal of Pharmacology 134:463-472. (Pubitemid 32977891)
    • (2001) British Journal of Pharmacology , vol.134 , Issue.3 , pp. 463-472
    • Wanstall, J.C.1    Jeffery, T.K.2    Gambino, A.3    Lovren, F.4    Triggle, C.R.5
  • 46
    • 0041422249 scopus 로고    scopus 로고
    • Genetic and environmental contributions to severe preeclampsia: Lack of association with the endothelial nitric oxide synthase Glu298Asp variant in a developing country
    • Yoshimura T, Chowdhury FA, Yoshimura M, Okamura H. 2003. Genetic and environmental contributions to severe preeclampsia: Lack of association with the endothelial nitric oxide synthase Glu298Asp variant in a developing country. Gynecologic and Obstetric Investigation 56:1013.
    • (2003) Gynecologic and Obstetric Investigation , vol.56 , pp. 1013
    • Yoshimura, T.1    Chowdhury, F.A.2    Yoshimura, M.3    Okamura, H.4


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