메뉴 건너뛰기




Volumn 2, Issue 10, 2011, Pages 973-976

A method for estimating the risk of drug-induced phototoxicity and its application to smoothened inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

1 PIPERAZINYLPHTHALAZINE DERIVATIVE; PHTHALAZINE DERIVATIVE; SMOOTHENED PROTEIN; UNCLASSIFIED DRUG;

EID: 80053604567     PISSN: 20402503     EISSN: 20402511     Source Type: Journal    
DOI: 10.1039/c1md00144b     Document Type: Article
Times cited : (21)

References (26)
  • 25
    • 78650522424 scopus 로고    scopus 로고
    • Mekenyan et al., Chemosphere 1994, 28, 567 demonstrated in their work on the phototoxicity of PAH to aquatic organisms that AM1 and PM3 calculations for the HOMO-LUMO gap of the ground state provided the same qualitative results. In regards to model performance it is possible that an assessment of frontier orbital energy could be more accurate if using ab initio methods. However, to rapidly screen larger sets of compounds we chose a semi-empirical method
    • S. Ringeissen L. Marrot R. Note A. Labarussiat S. Imbert M. Todorov O. Mekenyan J. R. Meunier Toxicol. in Vitro 2011 25 324
    • (2011) Toxicol. in Vitro , vol.25 , pp. 324
    • Ringeissen, S.1    Marrot, L.2    Note, R.3    Labarussiat, A.4    Imbert, S.5    Todorov, M.6    Mekenyan, O.7    Meunier, J.R.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.