Development of an expert system rulebase for the prospective identification of photoallergens

Journal of Photochemistry and Photobiology B: Biology

Volumn 58, Issue 1, 2000, Pages 54-61

  Barratt, Martin D ^a   Castell, José V ^b   Miranda, Miguel A ^c   Langowski, Jan J ^d  

^a Marlin Consultancy   (United Kingdom)

^b HOSPITAL UNIVERSITARIO LA FE   (Spain)

^c UNIVERSITAT POLITÈCNICA DE VALÈNCIA   (Spain)

^d UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

DEREK; Identification; Partition parameters; Photoallergens

Indexed keywords

CONTACT ALLERGEN;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; COMPUTER SYSTEM; CONTROLLED STUDY; DATA BASE; GERMANY; GUINEA PIG; HEALTH CARE ORGANIZATION; INFORMATION PROCESSING; NONHUMAN; PHOTOALLERGY; PRACTICE GUIDELINE; PRIORITY JOURNAL; QUALITY CONTROL; SKIN SENSITIVITY; SKIN SENSITIZATION; STRUCTURE ANALYSIS; TOXICITY TESTING; VALIDATION PROCESS;

ALLERGENS; ANIMALS; COUMARINS; EXPERT SYSTEMS; GUINEA PIGS; KETONES; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034529708     PISSN: 10111344     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1011-1344(00)00100-7     Document Type: Article

References (42)

1. Photoallergy - A review
2. Photoallergic responses to chemicals
3. Computer prediction of possible toxic action from chemical structure; The DEREK system
4. Computer prediction of possible toxic action from chemical structure: An update on the DEREK system
5. Validation and subsequent development of the DEREK skin sensitization rulebase by analysis of the BgVV list of contact allergens
6. Photodermatitis due to tetrachlorosalicylanilide
7. Photoallergic contact dermatitis
8. Photoallergisches Ekzem durch das Antimykotikum 4-Clor-2-hydroxybenzoesaure-N-n-butylamid Jadit
9. Contact photodermatitis from bithionol
10. Photoallergies to fentichlor and multifungin
11. Photochemical binding of photoallergens to human serum albumin: A simple in vitro method for screening potential photoallergens
12. Molecular basis of photocontact allergy
13. An electron spin resonance study of the free radicals formed on ultraviolet irradiation of the photoallergens fentichlor and bithionol
14. Free radicals in drug-induced photosensitivity reactions: Spin trapping study of photoallergenic halogenated salicylanilides
15. Phototoxische und Photoallergische Reaktionen: Moglichkeiten der Risikoabschatzung in der praklinischen und klinischen Entwicklung
16. Photoallergic reaction to carprofen
17. Photosensitivity associated with carprofen (Imadyl), a new non-steroidal anti-inflammatory drug
18. Photosensitivity induced by lomefloaxacin with cross-photosensitivity to ciprofloxacin and fleroxacin
19. Photogenotoxicity of skin phototumorigenic fluoroquinolone antibiotics detected using the comet assay
20. Case of photodermatosis due to long term treatment with amiodarone
21. Photochemistry and photobiological properties of dicloran, a post-harvest fungicide with photosensitizing side-effects
22. Contact dermatitis from diazepoxides
23. Occupational photocontact dermatitis from olaquindox
24. Experimental photoallergic contact dermatitis: A mouse model
25. Photobinding of some 7-chloro-1,4-benzodiazepines to human plasma protein in vitro and photopharmacology of diazepam in the rat
26. Photochemical reactions of quindoxin, carbadox and cyadox with protein, indicating photoallergic properties
27. In vitro- und in vivo-Untersuchungen zur fotochemische Reaktivitat von Methaqualon-1-oxid
28. Contact and photocontact allergy to ketoprofen - Clinical and experimental study
29. Topical nonsteroidal anti-inflammatory drugs: Allergic and photoallergic contact dermatitis and phototoxicity
30. Photoallergy induced by fenofibrate
31. Allergic photocontact dermatitis due to suprofen, photopatch testing and cross-reaction study
32. Photosensitizing drugs containing the benzophenone chromophore
33. Photoallergenicity testing of fragrance material. A review on photoallergy by musk ambrette in male human patients
34. Photosensitivity to musk ambrette
35. Spectroscopic studies of cutaneous photosensitizing agents. VI. Identification of the free radicals generated during the photolysis of musk ambrette, musk xylene and musk ketone
36. Medicinal photochemistry; phototoxic and phototherapeutic aspects of drugs
37. Photomazimisation test for identifying contact sensitisers
38. Photobinding of 8-methoxypsoralen, 4,6,4'-trimethylangelicin and chlorpromazine to Wistar rat epidermal biomacromolecules in vivo
39. Psoralen-protein photochemistry - A forgotten field
40. Physico-chemical descriptors
41. Quantitative structure-activity relationships for skin permeability