Aseptic loosening of total hip replacement. Macrophage expression of inducible nitric oxide synthase and cyclo-oxygenase-2, together with peroxynitrite formation, as a possible mechanism for early prosthesis failure

Journal of Bone and Joint Surgery - Series B

Volumn 79, Issue 3, 1997, Pages 467-474

  Hukkanen, M ^a,b   Corbett, S A ^a,b   Batten, J ^a,b   Konttinen, Y T ^a,c   McCarthy, I D ^a,b   Maclouf, J ^a,d   Santavirta, S ^a,e   Hughes, S P F ^a,b   Polak, J M ^a,b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c UNIVERSITY OF HELSINKI   (Finland)

^d HÔPITAL LARIBOISIÈRE   (France)

^e HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CD68 ANTIGEN; CYCLOOXYGENASE 2; CYTOKINE; NITRIC OXIDE SYNTHASE; PEROXYNITRITE; PROSTAGLANDIN E2; PROSTANOID;

ADULT; AGED; ARTICLE; CELL DAMAGE; CLINICAL ARTICLE; ENZYME ACTIVITY; ENZYME IMMUNOASSAY; FEMALE; GENE EXPRESSION; HUMAN; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE TEST; IMMUNOREACTIVITY; MACROPHAGE; MALE; OSTEOLYSIS; PHAGOCYTOSIS; PRIORITY JOURNAL; PROSTHESIS LOOSENING; TOTAL HIP PROSTHESIS;

ADOLESCENT; ADULT; AGED; CYCLOOXYGENASE 2; DINOPROSTONE; ENZYME INDUCTION; FEMALE; HIP PROSTHESIS; HUMANS; IMMUNOHISTOCHEMISTRY; ISOENZYMES; MACROPHAGES; MALE; MEMBRANE PROTEINS; MIDDLE AGED; NITRATES; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTHESIS FAILURE; REOPERATION; TIME FACTORS;

EID: 0030943994     PISSN: 0301620X     EISSN: None     Source Type: Journal    
DOI: 10.1302/0301-620X.79B3.7469     Document Type: Article

References (36)

1. Santavirta S, Konttinen YT, Bergroth V, et al. Aggressive granulomatous lesions associated with hip arthroplasty: immunopathological studies. J Bone Joint Surg [Am] 1990;72-A:252-8.
2. Schmalzried TP, Kwong LM, Jasty M, et al. The mechanism of loosening of cemented acetabular components in total hip arthroplasty: analysis of specimens retrieved at autopsy. Clin Orthop 1992;274:60-78.
3. Murray DW, Rushton N. Macrophages stimulate bone resorption when they phagocytose particles. J Bone Joint Surg [Br] 1990;72-B: 988-92.
4. Amstutz HC, Campbell P, Kossovsky N, Clarke IC. Mechanism and clinical significance of wear debris induced osteolysis. Clin Orthop 1992;276:7-18.
5. Jiranek WA, Machado M, Jasty M, et al. Production of cytokines around loosened cemented acetabular components: analysis with immunohistochemical techniques and in situ hybridization. J Bone Joint Surg [Am] 1993;75-A:863-79.
6. Al Saffar N, Revell PA. Interleukin-1 production by activated macrophages surrounding loosened orthopaedic implants: a potential role in osteolysis. Br J Rheumatol 1994;33:309-16.
7. Chiba J, Rubash HE, Kim KJ, Iwaki Y. The characterisation of cytokines in the interface tissue obtained from failed cementless total hip arthroplasty with and without femoral osteolysis. Clin Orthop 1994;300:304-12.
8. Sedel L, Simeon J, Meunier A, Villette JM, Launay SM. Prostaglandin E2 level in tissue surrounding aseptic failed total hips: effects of materials. Arch Orthop Trauma Surg 1992;111:255-8.
9. Konttinen YT, Kurvinen H, Takagi M, et al. IL-1 and collagenases around loose total hip prosthesis. Clin Exp Rheumatol 1996; 14:255-62.
10. Westacott CI, Taylor G, Atkins R, Elson C. Interleukin-1 alpha and beta production by cells isolated from membranes around aseptically loose total joint replacements. Ann Rheum Dis 1992;51:638-42.
11. Algan SM, Purdon M, Horowitz SM. Role of tumor necrosis factor alpha in particulate-induced bone resorption. J Orthop Res 1996; 14:30-5.
12. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J 1992;6:3051-64.
13. Wu KK. Inducible cyclooxygenase and nitric oxide synthase. Adv Pharmcol 1995;33:179-207.
14. Herschman HR. Prostaglandin synthase 2. Biochim Biophys Acta 1996;1299:125-40.
15. Ralston SH, Todd D, Helfrich M, Benjamin N, Grabowski PS. Human osteoblast-like cells produce nitric oxide and express inducible nitric oxide synthase. Endocrinology 1994;135:330-6.
16. Hukkanen M, Hughes FJ, Buttery LDK, et al. Cytokine-stimulated expression of nitric oxide synthase by mouse, rat and human osteoblast-like cells and its functional role in osteoblast metabolism. Endocrinology 1995;136:5445-53.
17. Buttery LDK, Hukkanen MVJ, O'Donnell A, et al. Nitric oxide dependent and independent induction of prostaglandin synthesis in osteoblasts. Bone 1995;17:560.
18. McCartney-Francis N, Allen JB, Mizel DE, et al. Suppression of arthritis by an inhibitor of nitric oxide synthase. J Exp Med 1993;178:749-54.
19. Stefanovic-Racic M, Meyers K, Meschter C, et al. N-monomethyl arginine, an inhibitor of nitric oxide synthase, suppresses the development of adjuvant arthritis in rats. Arthritis Rheum 1994;37:1062-9.
20. Farrell AJ, Blake DR, Palmer RM, Moncada S. Increased concentrations of nitrite in synovial fluid and serum samples suggest increased nitric oxide synthesis in rheumatic diseases. Ann Rheum Dis 1992;51:1219-22.
21. Kaur H, Halliwell B. Evidence for nitric oxide-mediated oxidative damage in chronic inflammation: nitrotyrosine in serum and synovial fluid from rheumatoid patients. FEBS Lett 1994;350:9-12.
22. Stichtenoth DO, Fauler J, Zeidler H, Frölich JC. Urinary nitrate excretion is increased in patients with rheumatoid arthritis and reduced by prednisolone. Ann Rheum Dis 1995;54:820-4.
23. Sakurai H, Kohsaka H, Liu M-F, et al. Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides. J Clin Invest 1995;96:2357-63.
24. MacIntyre I, Zaidi M, Towhidul Alam AS, et al. Osteoclastic inhibition: an action of nitric oxide not mediated by cyclic GMP. Proc Natl Acad Sci USA 1991;88:2936-40.
25. Brandi ML, Hukkanen M, Umeda T, et al. Bidirectional regulation of osteoclast function by nitric oxide synthase isoforms. Proc Natl Acad Sci USA 1995;92:2954-8.
26. Beckman JS, Chen J, Crow JP, Ye YZ. Reactions of nitric oxide, superoxide and peroxynitrite with superoxide dismutase in neurodegeneration. In: Seil FJ, ed. Prog brain res Vol 103, 1994:103:371-80.
27. Stamler JS. Redox signalling: nitrosylation and related target interactions of nitric oxide. Cell 1994;78:931-6.
28. Buttery LDK, Springall DR, Chester AH, et al. Inducible nitric oxide synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite. Lab Invest 1996;75:77-85.
29. Haddad IY, Pataki G, Hu P, et al. Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury. J Clin Invest 1994;94:2407-13.
30. Garrett IR, Boyce BF, Oreffo RO, et al. Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo. J Clin Invest 1990;85:632-9.
31. Paul-Eugene N, Mossalayi D, Sarfati M, et al. Evidence for a role of FC epsilon RII/CD23 in the IL-4-induced nitric oxide production by normal human mononuclear phagocytes. Cell Immunol 1995;163: 314-8.
32. Hughes FJ, Ghazi R, Hukkanen M, Buttery L, Polak JM. Cytokine-induced apoptosis in osteoblast cultures mediated by nitric oxide. Bone 1995;17:565.
33. Pitsillides AA, Rawlinson SC, Suswillo RF, et al. Mechanical strain-induced NO production by bone cells: a possible role in adaptive bone (re)modelling? FASEB J 1995;9:1614-22.
34. Hukkanen M, Pitsillides AA, Rawlinson SCF, et al. A putative role for osteocyte eNOS-derived NO in adaptive bone remodelling. J Pathol (Abstract), in press, 1996.
35. Fox SW, Chambers TJ, Chow JW. Nitric oxide is an early mediator of the increase in bone formation by mechanical stimulation. Am J Physiol 1996;270:955-60.
36. Turner CH, Takano Y, Owan I, Murrell GAC. Nitric oxide inhibitor L-NAME suppresses mechanically induced bone formation in rats. Am J Physiol 1996;270:E634-9.