Studies on target tissue distribution of ginsenosides and epimedium flavonoids in rats after intravenous administration of Jiweiling freeze-dried powder

Biomedical Chromatography

Volumn 25, Issue 11, 2011, Pages 1260-1272

  Liu, Minyan ^a,b   Wang, Hongtao ^b   Zhao, Shaohua ^b   Shi, Xiaowei ^a   Zhang, Yongfeng ^b   Xu, Honghui ^b   Wang, Yufeng ^b   Li, Xiangjun ^b   Zhang, Lantong ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b Key Laboratory of State Administration of TCM   (China)

Author keywords

Epimedium flavonoids; Ginsenosides; HPLC ESI MS MS; Jiweiling freeze dried powder; Target tissue distribution

Indexed keywords

ELECTROSPRAY IONIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRECIPITATION (CHEMICAL); RATS; TISSUE;

DRIED POWDER; EPIMEDIUM; EPIMEDIUM FLAVONOID; FLAVONOID; GINSENOSIDES; HPLC-ELECTROSPRAY IONIZATION-MS/MS; JIWEILING FREEZE-DRIED POWDER; TARGET TISSUE DISTRIBUTION; TARGET TISSUES; TISSUE DISTRIBUTIONS;

FLAVONOIDS;

ACETONITRILE; CHINESE DRUG; EPIMEDIN A; EPIMEDIN B; EPIMEDIN C; FLAVONOID; FORMIC ACID; GENISTEIN; GINSENOSIDE; GINSENOSIDE RB 1; GINSENOSIDE RB 2; GINSENOSIDE RC; GINSENOSIDE RD; GINSENOSIDE RE; GINSENOSIDE RF; GINSENOSIDE RG 1; ICARIIN; JIWEILING; UNCLASSIFIED DRUG; HERBACEOUS AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; BRAIN; CALIBRATION; CHINESE HERB; CONTROLLED STUDY; CORRELATION COEFFICIENT; DRUG STRUCTURE; DRUG TISSUE LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MUSCLE; NONHUMAN; PRECIPITATION; QUANTITATIVE ANALYSIS; RAT; SCIATIC NERVE; SENSITIVITY ANALYSIS; SPINAL CORD; TISSUE DISTRIBUTION; VALIDATION PROCESS; ANIMAL; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; EPIMEDIUM; INTRAVENOUS DRUG ADMINISTRATION; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SPRAGUE DAWLEY RAT; STATISTICAL MODEL;

EPIMEDIUM; RATTUS;

ADMINISTRATION, INTRAVENOUS; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; EPIMEDIUM; FLAVONOIDS; GINSENOSIDES; LINEAR MODELS; MALE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TISSUE DISTRIBUTION;

EID: 80053587833     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1600     Document Type: Article

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