Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 V H X V L knockin mice reveals multiple tolerance controls

Journal of Immunology

Volumn 187, Issue 7, 2011, Pages 3785-3797

  Verkoczy, Laurent ^a   Chen, Yao ^a   Bouton Verville, Hilary ^a   Zhang, Jinsong ^a   Diaz, Marilyn ^b   Hutchinson, Jennifer ^a   Ouyang, Ying Bin ^c   Alam, S Munir ^a   Holl, T Matt ^a   Hwang, Kwan Ki ^a   Kelsoe, Garnett ^a   Haynes, Barton F ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c Taconic Farms Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B CELL ACTIVATING FACTOR; IMMUNOGLOBULIN; INTERLEUKIN 7; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; NEUTRALIZING ANTIBODY 2F5; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ARTICLE; B LYMPHOCYTE; CLONAL ANERGY; CONTROLLED STUDY; GENE TARGETING; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; LYMPHOCYTOPOIESIS; MOUSE; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TRANSGENIC MOUSE; VIRUS ENVELOPE;

ANIMALS; ANTIBODIES, NEUTRALIZING; B-LYMPHOCYTES; CELL SEPARATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE KNOCK-IN TECHNIQUES; GENES, IMMUNOGLOBULIN; HIV INFECTIONS; HIV-1; IMMUNE TOLERANCE; IMMUNOGLOBULIN VARIABLE REGION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC;

EID: 80053529030     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1101633     Document Type: Article

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