메뉴 건너뛰기




Volumn 91, Issue 3, 2011, Pages 687-694

Liver mitochondrial function and redox status in an experimental model of non-alcoholic fatty liver disease induced by monosodium l-glutamate in rats

Author keywords

Mitochondria; MSG; NAFLD; Obesity; Oxidative stress; ROS

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CALCIUM ION; CATALASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; REACTIVE OXYGEN METABOLITE; SUCCINIC ACID; SUPEROXIDE DISMUTASE; THIOL; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 80053519285     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2011.07.003     Document Type: Article
Times cited : (37)

References (73)
  • 1
    • 24044536090 scopus 로고    scopus 로고
    • Recent concepts in non-alcoholic fatty liver
    • Adams L.A., Angulo P. Recent concepts in non-alcoholic fatty liver. Diabet. Med. 2005, 22:1129-1133.
    • (2005) Diabet. Med. , vol.22 , pp. 1129-1133
    • Adams, L.A.1    Angulo, P.2
  • 2
    • 17444417085 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Adams L.A., Angulo P., Lindor K.D. Nonalcoholic fatty liver disease. CMAJ 2005, 172:899-905.
    • (2005) CMAJ , vol.172 , pp. 899-905
    • Adams, L.A.1    Angulo, P.2    Lindor, K.D.3
  • 3
    • 0000024078 scopus 로고
    • Catalase
    • Academic Press, New York, H.U. Bergmeyer (Ed.)
    • Aebi H. Catalase. Methods of enzymatic analysis 1974, 673-690. Academic Press, New York. H.U. Bergmeyer (Ed.).
    • (1974) Methods of enzymatic analysis , pp. 673-690
    • Aebi, H.1
  • 4
    • 0036207189 scopus 로고    scopus 로고
    • Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2
    • Baffy G., Zhang C.Y., Glickman J.N., Lowell B.B. Obesity-related fatty liver is unchanged in mice deficient for mitochondrial uncoupling protein 2. Hepatology 2002, 35:753-761.
    • (2002) Hepatology , vol.35 , pp. 753-761
    • Baffy, G.1    Zhang, C.Y.2    Glickman, J.N.3    Lowell, B.B.4
  • 6
    • 32844458032 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it
    • Begriche K., Igoudjil A., Pessayre D., Fromenty B. Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it. Mitochondrion 2006, 6:1-28.
    • (2006) Mitochondrion , vol.6 , pp. 1-28
    • Begriche, K.1    Igoudjil, A.2    Pessayre, D.3    Fromenty, B.4
  • 7
    • 0026801183 scopus 로고
    • Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by the proton electrochemical gradient. Evidence that the pore can be opened by membrane despolarization
    • Bernardi P. Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by the proton electrochemical gradient. Evidence that the pore can be opened by membrane despolarization. J. Biol. Chem. 1992, 267:8834-8839.
    • (1992) J. Biol. Chem. , vol.267 , pp. 8834-8839
    • Bernardi, P.1
  • 8
    • 0014273763 scopus 로고
    • Correlation between 'Lee index' and carcass fat content in weanling and adult female rats with hypothalamic lesions
    • Bernardis L.L., Patterson B.D. Correlation between 'Lee index' and carcass fat content in weanling and adult female rats with hypothalamic lesions. J. Endocrinol. 1968, 40:527-528.
    • (1968) J. Endocrinol. , vol.40 , pp. 527-528
    • Bernardis, L.L.1    Patterson, B.D.2
  • 10
    • 0033969421 scopus 로고    scopus 로고
    • Uncoupling proteins 2 and 3: potential regulators of mitochondrial energy metabolism
    • Boss O., Hagen T., Lowell B.B. Uncoupling proteins 2 and 3: potential regulators of mitochondrial energy metabolism. Diabetes 2000, 49:143-156.
    • (2000) Diabetes , vol.49 , pp. 143-156
    • Boss, O.1    Hagen, T.2    Lowell, B.B.3
  • 11
  • 12
    • 2442507165 scopus 로고    scopus 로고
    • O estudo do metabolismo energético em mitocÔndrias isoladas de tecido animal
    • Manole Ltda, São Paulo, A. Bracht, E.L. Ishii-Iwamoto (Eds.)
    • Bracht A., Ishii-Iwamoto E.L., Salgueiro-Pagadigorria C.L. O estudo do metabolismo energético em mitocÔndrias isoladas de tecido animal. Métodos de laboratório em bioquímica 2003, 227-247. Manole Ltda, São Paulo. A. Bracht, E.L. Ishii-Iwamoto (Eds.).
    • (2003) Métodos de laboratório em bioquímica , pp. 227-247
    • Bracht, A.1    Ishii-Iwamoto, E.L.2    Salgueiro-Pagadigorria, C.L.3
  • 13
    • 0022007068 scopus 로고
    • Elevated hepatic mitochondrial and peroxisomal oxidative capacities in fed and starved adult obese (ob/ob) mice
    • Brady L.J., Brady P.S., Romsos D.R., Hoppel C.L. Elevated hepatic mitochondrial and peroxisomal oxidative capacities in fed and starved adult obese (ob/ob) mice. Biochem. J. 1985, 231:439-444.
    • (1985) Biochem. J. , vol.231 , pp. 439-444
    • Brady, L.J.1    Brady, P.S.2    Romsos, D.R.3    Hoppel, C.L.4
  • 15
    • 0000654355 scopus 로고
    • A simple and rapid assay of oxidative phosphorylation
    • Chance B., Williams G.R. A simple and rapid assay of oxidative phosphorylation. Nature 1955, 175:1120-1121.
    • (1955) Nature , vol.175 , pp. 1120-1121
    • Chance, B.1    Williams, G.R.2
  • 20
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: a tale of two "hits"?
    • Day C., James O. Steatohepatitis: a tale of two "hits"?. Gastroenterology 1998, 114:842-845.
    • (1998) Gastroenterology , vol.114 , pp. 842-845
    • Day, C.1    James, O.2
  • 21
    • 0029128915 scopus 로고
    • Alterations of peroxisomes in steatosis of the human liver: a quantitative study
    • De Craemer D., Pauwels M., Van den Branden C. Alterations of peroxisomes in steatosis of the human liver: a quantitative study. Hepatology 1995, 22:744-752.
    • (1995) Hepatology , vol.22 , pp. 744-752
    • De Craemer, D.1    Pauwels, M.2    Van den Branden, C.3
  • 24
    • 0036724436 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatites: a common cause of progressive chronic injury?
    • Evans C.D., Oien K.A., MacSween R.N.M., Mills P.R. Non-alcoholic steatohepatites: a common cause of progressive chronic injury?. J. Clin. Pathol. 2002, 55:689-692.
    • (2002) J. Clin. Pathol. , vol.55 , pp. 689-692
    • Evans, C.D.1    Oien, K.A.2    MacSween, R.N.M.3    Mills, P.R.4
  • 25
    • 0000154206 scopus 로고
    • The colorimetric determination of phosphorus
    • Fiske C.H., Subbarow Y. The colorimetric determination of phosphorus. J. Biol. Chem. 1925, 66:375-400.
    • (1925) J. Biol. Chem. , vol.66 , pp. 375-400
    • Fiske, C.H.1    Subbarow, Y.2
  • 26
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animal tissues
    • Folch J., Lees M., Sloane Stanley G.H. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 1957, 226:497-509.
    • (1957) J. Biol. Chem. , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 27
    • 0029127584 scopus 로고
    • Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity
    • Fromenty B., Pessayre D. Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity. Pharmacol. Ther. 1995, 67:101-154.
    • (1995) Pharmacol. Ther. , vol.67 , pp. 101-154
    • Fromenty, B.1    Pessayre, D.2
  • 29
    • 78449311681 scopus 로고
    • Interactions between fatty acid oxidation and the tricarboxylic acid cycle
    • Dekker, New York, J.M. Lowestein (Ed.)
    • Garland P.B., Shepherd D., Nicholls D.G., Yates D.W., Light P.A. Interactions between fatty acid oxidation and the tricarboxylic acid cycle. Citric Acid Cycle 1969, 163-212. Dekker, New York. J.M. Lowestein (Ed.).
    • (1969) Citric Acid Cycle , pp. 163-212
    • Garland, P.B.1    Shepherd, D.2    Nicholls, D.G.3    Yates, D.W.4    Light, P.A.5
  • 30
    • 0017064979 scopus 로고
    • A fluorometric method for determination of oxidized and reduced glutathione in tissues
    • Hissin P.J., Hilf R. A fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal. Biochem. 1976, 74:214-226.
    • (1976) Anal. Biochem. , vol.74 , pp. 214-226
    • Hissin, P.J.1    Hilf, R.2
  • 31
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
    • Hotamisligil G.S., Peralti S.P., Budavari A., Ellis R., White M.F., Spiegelman B.A. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 1996, 271:665-668.
    • (1996) Science , vol.271 , pp. 665-668
    • Hotamisligil, G.S.1    Peralti, S.P.2    Budavari, A.3    Ellis, R.4    White, M.F.5    Spiegelman, B.A.6
  • 32
    • 0033562693 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis: another disease of affluence
    • James O., Day C. Non-alcoholic steatohepatitis: another disease of affluence. Lancet 1999, 353:1634-1636.
    • (1999) Lancet , vol.353 , pp. 1634-1636
    • James, O.1    Day, C.2
  • 33
    • 0030602865 scopus 로고    scopus 로고
    • Inhibition of carnitine palmitoyltransferase-I in rat heart and liver by perhexiline and amiodarone
    • Kennedy J.A., Unger S.A., Horowitz J.D. Inhibition of carnitine palmitoyltransferase-I in rat heart and liver by perhexiline and amiodarone. Biochem. Pharmacol. 1996, 52:273-280.
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 273-280
    • Kennedy, J.A.1    Unger, S.A.2    Horowitz, J.D.3
  • 34
    • 0028968879 scopus 로고
    • The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase
    • Kern P.A., Saghizaheh M., Ong J.M., Bosch R.J., Deem R., Simsolo R.B. The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J. Clin. Invest. 1995, 95:2111-2119.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2111-2119
    • Kern, P.A.1    Saghizaheh, M.2    Ong, J.M.3    Bosch, R.J.4    Deem, R.5    Simsolo, R.B.6
  • 37
    • 13144253134 scopus 로고    scopus 로고
    • Leptin-like effects of MTII are augmented in MSG-obese rats
    • Kim Y.W., Choi D.W., Park Y.H., Huh J.Y., Won K.C. Leptin-like effects of MTII are augmented in MSG-obese rats. Regul. Pept. 2005, 127:63-70.
    • (2005) Regul. Pept. , vol.127 , pp. 63-70
    • Kim, Y.W.1    Choi, D.W.2    Park, Y.H.3    Huh, J.Y.4    Won, K.C.5
  • 38
    • 0028176627 scopus 로고
    • Glucose-6-phosphate dehydrogenase: a"housekeeping" enzyme subject to tissue-specific regulation by hormones, nutrients and oxidative stress
    • Kletzien R.F., Harris P.K., Foellmi L.A. Glucose-6-phosphate dehydrogenase: a"housekeeping" enzyme subject to tissue-specific regulation by hormones, nutrients and oxidative stress. FASEB J. 1994, 8:174-181.
    • (1994) FASEB J. , vol.8 , pp. 174-181
    • Kletzien, R.F.1    Harris, P.K.2    Foellmi, L.A.3
  • 39
    • 0031573552 scopus 로고    scopus 로고
    • 2+ acting at the external side of the inner mitochondrial membrane can stimulate mitochondrial permeability transition induced by phenylarsine oxide
    • 2+ acting at the external side of the inner mitochondrial membrane can stimulate mitochondrial permeability transition induced by phenylarsine oxide. Biochim. Biophys. Acta. 1997, 1322:221-229.
    • (1997) Biochim. Biophys. Acta. , vol.1322 , pp. 221-229
    • Kowaltowski, A.J.1    Castilho, R.F.2
  • 40
    • 0035917814 scopus 로고    scopus 로고
    • Mitochondrial permeability transition and oxidative stress
    • Kowaltowski A.J., Castilho F.R., Vercesi A.E. Mitochondrial permeability transition and oxidative stress. FEBS Lett. 2001, 495:12-15.
    • (2001) FEBS Lett. , vol.495 , pp. 12-15
    • Kowaltowski, A.J.1    Castilho, F.R.2    Vercesi, A.E.3
  • 42
    • 0022853586 scopus 로고
    • Behavioral and endocrinological effects of single injections of monosodium glutamate in the mouse
    • Lorden J.F., Caudle A. Behavioral and endocrinological effects of single injections of monosodium glutamate in the mouse. Neurobehav. Toxicol. Teratol. 1986, 8:509-519.
    • (1986) Neurobehav. Toxicol. Teratol. , vol.8 , pp. 509-519
    • Lorden, J.F.1    Caudle, A.2
  • 43
    • 0035865496 scopus 로고    scopus 로고
    • Long-chain fatty acid regulates liver carnitine palmitoyltransferase I gene (L-CPT I) expression through a peroxisome proliferator-activated receptor-α (PPAR-α)-independent pathway
    • Louet J.F., Chatelain F., Decaux J.F., Park E.A., Kohl C., Pineau T., Girard J., Pegorier J.P. Long-chain fatty acid regulates liver carnitine palmitoyltransferase I gene (L-CPT I) expression through a peroxisome proliferator-activated receptor-α (PPAR-α)-independent pathway. Biochem. J. 2001, 354:189-197.
    • (2001) Biochem. J. , vol.354 , pp. 189-197
    • Louet, J.F.1    Chatelain, F.2    Decaux, J.F.3    Park, E.A.4    Kohl, C.5    Pineau, T.6    Girard, J.7    Pegorier, J.P.8
  • 45
    • 0034084335 scopus 로고    scopus 로고
    • Late effects of postnatal administration of monosodium glutamate on insulin action in adult rats
    • Macho L., Ficková M., Jezová, Zórad S. Late effects of postnatal administration of monosodium glutamate on insulin action in adult rats. Physiol. Res. 2000, 49:79-85.
    • (2000) Physiol. Res. , vol.49 , pp. 79-85
    • Macho, L.1    Ficková, M.2    Jezová Zórad, S.3
  • 46
    • 0016272750 scopus 로고
    • Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase
    • Marklund S., Marklund G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem. 1974, 47:469-474.
    • (1974) Eur. J. Biochem. , vol.47 , pp. 469-474
    • Marklund, S.1    Marklund, G.2
  • 47
    • 0033695790 scopus 로고    scopus 로고
    • Up-regulation of peroxisome proliferator-activated receptors (PPAR-α) and PPAR-γ messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-γ-responsive adipose tissue-specific genes in the liver of obese diabetic mice
    • Memon R.A., Tecott L.H., Nonogaki K., Beigneux A., Moser A.H., Grunfeld C., Feingold K.R. Up-regulation of peroxisome proliferator-activated receptors (PPAR-α) and PPAR-γ messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-γ-responsive adipose tissue-specific genes in the liver of obese diabetic mice. Endocrinology 2000, 41:4021-4031.
    • (2000) Endocrinology , vol.41 , pp. 4021-4031
    • Memon, R.A.1    Tecott, L.H.2    Nonogaki, K.3    Beigneux, A.4    Moser, A.H.5    Grunfeld, C.6    Feingold, K.R.7
  • 48
    • 0001108928 scopus 로고
    • Hepatic glutathione reductase. Purification and general kinetic properties
    • Mize C.E., Langdon R.G. Hepatic glutathione reductase. Purification and general kinetic properties. J. Biol. Chem. 1962, 237:1589-1595.
    • (1962) J. Biol. Chem. , vol.237 , pp. 1589-1595
    • Mize, C.E.1    Langdon, R.G.2
  • 49
    • 0037088649 scopus 로고    scopus 로고
    • Mechanism for peroxisome proliferator-activated receptor-α activator-induced up-regulation of UCP-2 mRNA in rodent hepatocytes
    • Nakatani T., Tsuboyama-Kasaoka N., Takahashi M., Miura S., Ezaki O. Mechanism for peroxisome proliferator-activated receptor-α activator-induced up-regulation of UCP-2 mRNA in rodent hepatocytes. J. Biol. Chem. 2002, 277:9562-9569.
    • (2002) J. Biol. Chem. , vol.277 , pp. 9562-9569
    • Nakatani, T.1    Tsuboyama-Kasaoka, N.2    Takahashi, M.3    Miura, S.4    Ezaki, O.5
  • 50
    • 77950361229 scopus 로고    scopus 로고
    • The effect of tert-butylhydroquinone-induced oxidative stress in MDBK cells using XTT assay: implication of tert-butylhydroquinone-induced NADPH generating enzymes
    • Naoi T., Shibuya N., Inoue H., Mita S., Kobayashi S., Watanabe K., Orino K. The effect of tert-butylhydroquinone-induced oxidative stress in MDBK cells using XTT assay: implication of tert-butylhydroquinone-induced NADPH generating enzymes. J. Vet. Med. Sci. 2010, 72:321-326.
    • (2010) J. Vet. Med. Sci. , vol.72 , pp. 321-326
    • Naoi, T.1    Shibuya, N.2    Inoue, H.3    Mita, S.4    Kobayashi, S.5    Watanabe, K.6    Orino, K.7
  • 51
    • 33745844419 scopus 로고    scopus 로고
    • Oxidative stress in experimental liver microvesicular steatosis: role of mitochondria and peroxisomes
    • Natarajan S.K., Eapen C.E., Olimood A.B., Balasubramanian K.A. Oxidative stress in experimental liver microvesicular steatosis: role of mitochondria and peroxisomes. Hepatology 2006, 21:1240-1249.
    • (2006) Hepatology , vol.21 , pp. 1240-1249
    • Natarajan, S.K.1    Eapen, C.E.2    Olimood, A.B.3    Balasubramanian, K.A.4
  • 53
    • 0017590814 scopus 로고
    • Obesity in exercising, hypohagic rats treated with monosodium glutamate
    • Nikoletseas M.M. Obesity in exercising, hypohagic rats treated with monosodium glutamate. Physiol. Behavior 1977, 19:767-773.
    • (1977) Physiol. Behavior , vol.19 , pp. 767-773
    • Nikoletseas, M.M.1
  • 55
    • 0014668762 scopus 로고
    • Brain lesions, obesity and other disturbances in mice treated with monosodium glutamate
    • Olney J.W. Brain lesions, obesity and other disturbances in mice treated with monosodium glutamate. Science 1969, 164:719-721.
    • (1969) Science , vol.164 , pp. 719-721
    • Olney, J.W.1
  • 56
    • 0014108436 scopus 로고
    • Studies on the quantitative and qualitative characterization of erythrocyte glutatione peroxidase
    • Paglia E.D., Valentine W.N. Studies on the quantitative and qualitative characterization of erythrocyte glutatione peroxidase. J. Lab. Clin. Med. 1967, 70:158-169.
    • (1967) J. Lab. Clin. Med. , vol.70 , pp. 158-169
    • Paglia, E.D.1    Valentine, W.N.2
  • 57
    • 20344373410 scopus 로고    scopus 로고
    • Overexpression of glucose-6-phosphate dehydrogenase is associated with lipid dysregulation and insulin resistance in obesity
    • Park J., Rho H.K., Kim K.H., Choe S.S., Lee Y.S., Kim J.B. Overexpression of glucose-6-phosphate dehydrogenase is associated with lipid dysregulation and insulin resistance in obesity. Mol. Cell. Biol. 2005, 25:5146-5157.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 5146-5157
    • Park, J.1    Rho, H.K.2    Kim, K.H.3    Choe, S.S.4    Lee, Y.S.5    Kim, J.B.6
  • 58
    • 33845596741 scopus 로고    scopus 로고
    • Increase in glucose-6-phosphate dehydrogenase in adipocytes stimulates oxidative stress and inflammatory signals
    • Park J., Choe S.S., Choi A.H., Kim K.H., Yoon M.J., Suganami T., Ogawa Y., Kim J.B. Increase in glucose-6-phosphate dehydrogenase in adipocytes stimulates oxidative stress and inflammatory signals. Diabetes 2006, 55:2939-2949.
    • (2006) Diabetes , vol.55 , pp. 2939-2949
    • Park, J.1    Choe, S.S.2    Choi, A.H.3    Kim, K.H.4    Yoon, M.J.5    Suganami, T.6    Ogawa, Y.7    Kim, J.B.8
  • 60
    • 39849099669 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease and the metabolic syndrome: an update
    • Rector R.S., Thyfault J.P., Wei Y., Ibdah J.A. Non-alcoholic fatty liver disease and the metabolic syndrome: an update. World J. Gastroenterol. 2008, 14:185-192.
    • (2008) World J. Gastroenterol. , vol.14 , pp. 185-192
    • Rector, R.S.1    Thyfault, J.P.2    Wei, Y.3    Ibdah, J.A.4
  • 62
    • 0029873873 scopus 로고    scopus 로고
    • Prevention of diabetic alterations in transgenic mice overexpressing Myc in the liver
    • Riu E., Bosch F., Valera A. Prevention of diabetic alterations in transgenic mice overexpressing Myc in the liver. Proc. Natl. Acad. Sci. USA 1996, 93:2198-2202.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 2198-2202
    • Riu, E.1    Bosch, F.2    Valera, A.3
  • 65
    • 0037160091 scopus 로고    scopus 로고
    • Topology of superoxide production from different sites in the mitochondrial electron transport chain
    • St-Pierre J., Buckingham J.A., Roebuck S.J., Brand M.D. Topology of superoxide production from different sites in the mitochondrial electron transport chain. J. Biol. Chem. 2002, 277:44784-44790.
    • (2002) J. Biol. Chem. , vol.277 , pp. 44784-44790
    • St-Pierre, J.1    Buckingham, J.A.2    Roebuck, S.J.3    Brand, M.D.4
  • 66
    • 0018146437 scopus 로고
    • Studies on brain lesion by administration of monosodium l-glutamate to mice. I. Brain lesions in infant mice caused by administration of monosodium L-glutamate
    • Takasaki Y. Studies on brain lesion by administration of monosodium l-glutamate to mice. I. Brain lesions in infant mice caused by administration of monosodium L-glutamate. Toxicology 1978, 9:293-305.
    • (1978) Toxicology , vol.9 , pp. 293-305
    • Takasaki, Y.1
  • 67
    • 0028229095 scopus 로고
    • Signal transduction proteins that associate with the platelet-derived growth factor (PDGF) receptor mediate the PDGF-induced release of glucose-6-phosphate dehydrogenase from permeabilized cells
    • Tian W.N., Pignatare N., Stanton R.C. Signal transduction proteins that associate with the platelet-derived growth factor (PDGF) receptor mediate the PDGF-induced release of glucose-6-phosphate dehydrogenase from permeabilized cells. J. Biol. Chem. 1994, 269:14798-14805.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14798-14805
    • Tian, W.N.1    Pignatare, N.2    Stanton, R.C.3
  • 69
    • 34547588219 scopus 로고    scopus 로고
    • Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents
    • Turner N., Bruce C.R., Beale S.M., Hoehn K.L., So T., Rolph M.S., Cooney G.J. Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents. Diabetes 2007, 56:2085-2092.
    • (2007) Diabetes , vol.56 , pp. 2085-2092
    • Turner, N.1    Bruce, C.R.2    Beale, S.M.3    Hoehn, K.L.4    So, T.5    Rolph, M.S.6    Cooney, G.J.7
  • 70
    • 0031795059 scopus 로고    scopus 로고
    • Disruption of mitochondrial activity in rabbit and human hepatocytes by a quinoxalinone anxiolytic and its carboxylic acid metabolite
    • Ulrich R.G., Bacon J.A., Cramer C.T., Petrella D.K., Sun E.L., Meglasson M.D., Holmuhamedov E. Disruption of mitochondrial activity in rabbit and human hepatocytes by a quinoxalinone anxiolytic and its carboxylic acid metabolite. Toxicology 1998, 131:33-47.
    • (1998) Toxicology , vol.131 , pp. 33-47
    • Ulrich, R.G.1    Bacon, J.A.2    Cramer, C.T.3    Petrella, D.K.4    Sun, E.L.5    Meglasson, M.D.6    Holmuhamedov, E.7
  • 71
    • 0030756346 scopus 로고    scopus 로고
    • Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function
    • Uysal K.T., Wiesbrock S.M., Marino M.W., Hotamisligil G.S. Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature 1997, 389:610-614.
    • (1997) Nature , vol.389 , pp. 610-614
    • Uysal, K.T.1    Wiesbrock, S.M.2    Marino, M.W.3    Hotamisligil, G.S.4
  • 72
    • 7144229334 scopus 로고    scopus 로고
    • Changes in glucose metabolising enzymes in adjuvant arthritis and its treatment with a Siddha drug: Serankottai Nei. Indian
    • Vijayalakshmi T., Jayaprakash N.P., Sachdanandam P. Changes in glucose metabolising enzymes in adjuvant arthritis and its treatment with a Siddha drug: Serankottai Nei. Indian. J. Pharmacol. 1998, 30:89-93.
    • (1998) J. Pharmacol. , vol.30 , pp. 89-93
    • Vijayalakshmi, T.1    Jayaprakash, N.P.2    Sachdanandam, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.