Human leptin tissue distribution, but not weight loss-dependent change in expression, is associated with methylation of its promoter

Epigenetics

Volumn 6, Issue 10, 2011, Pages 1198-1206

  Marchi, Matilde ^a,b   Lisi, Simonetta ^a,b   Curcio, Michele ^b   Barbuti, Serena ^b   Piaggi, Paolo ^c   Ceccarini, Giovanni ^b   Nannipieri, Monica ^c   Anselmino, Marco ^d   di Salvo, Claudio ^b   Vitti, Paolo ^b   Pinchera, Aldo ^b   Santini, Ferruccio ^b   Maffei, Margherita ^a,b,e  

^a DULBECCO TELETHON INSTITUTE   (Italy)

^b UNIVERSITY HOSPITAL OF PISA   (Italy)

^c UNIVERSITY OF PISA   (Italy)

^d Bariatric Surgery Unit   (Italy)

^e CNR   (Italy)

Author keywords

Adipocyte; CpG islands; Decitabine; Gastric bypass; Leptin; Methylation; Tissue specificity; Weight loss

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CCAAT ENHANCER BINDING PROTEIN; LEPTIN; TRANSCRIPTION FACTOR SP1;

ADULT; ARTICLE; BARIATRIC SURGERY; CELL DIFFERENTIATION; CONTROLLED STUDY; DEMETHYLATION; DNA METHYLATION; FIBROBLAST; GENE EXPRESSION; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRAABDOMINAL FAT; LIVER; LONGITUDINAL STUDY; NUCLEOTIDE SEQUENCE; PROMOTER REGION; TATA BOX; TISSUE DISTRIBUTION; WEIGHT REDUCTION; WHITE ADIPOSE TISSUE;

EID: 80053452296     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.6.10.16600     Document Type: Article

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